Devendra Singh

Dr. Devendra Singh

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Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 August 2024 in Bulletin of the National Research Centre
Verified
Journal Article
Open access
PDF file
SVSunil Kumar Verma
Sunil Kumar Verma
MPMinakshi Pandey
Minakshi Pandey
ASAvinash Sharma
Avinash Sharma
DSDevendra Singh
Devendra Singh
Background: The integration of Ayurveda, Yoga, Unani, Siddha, and Homeopathy (AYUSH) with modern medicine aims to provide a more personalized and effective approach to healthcare. Ayurveda is a traditional medicine system in India that emphasizes the balance between mind, body, and spirit. It is based on the belief that every individual is unique and requires personalized treatment. The fundamental principles of Ayurveda revolve around maintaining equilibrium among three doshas: Vata (air and space), Pitta (fire and water), and Kapha (earth and water). Imbalances in these doshas are believed to cause diseases. Main body of the The integration of Ayurveda with modern medicine seeks to utilize the best of both systems, focusing on using natural remedies and treatments that have been used for centuries in Ayurveda. The integration involves combining the strengths of both systems, including the use of Ayurvedic principles in modern medicine and the incorporation of modern medicine into Ayurvedic practices. Several studies have explored the efficacy of Ayurvedic treatments for various diseases, and the integration of Ayurvedic principles into modern medicine can provide a more comprehensive approach to patient care. Short conclusion: Ayurveda is a traditional medical system deeply rooted in Indian culture that offers a holistic approach to healthcare. Its principles emphasize personalized treatment based on an individual's constitution. Integrating Ayurveda with modern medicine can enhance patient care by providing a more comprehensive approach towards health management. However, challenges exist regarding the standardization of Ayurvedic practices due to variations in formulations and the need for more scientific evidence for some treatments. Further studies are needed for validation purposes.

20 December 2024 in Cancer Treatment and Research Communications
Verified
Journal Article
Open access
DSDevendra Singh
Devendra Singh
MPMinakshi Pandey
Minakshi Pandey
VDVivek Kumar Dhiman
Vivek Kumar Dhiman
ASAvinash Sharma
Avinash Sharma
HPHimanshu Pandey
Himanshu Pandey
RPRajeev Pandey
Rajeev Pandey
The incidence of cancer continues to increase worldwide, resulting in significant physical, emotional, and financial challenges for individuals, families, communities, and healthcare systems. Cancer is projected to be responsible for approximately 10 million deaths in 2020, accounting for one in six deaths globally. Prostate, colon, lung, and breast cancers are the most common types of cancer. In India, it is estimated that there will be around 2.7 million cancer patients by 2020. Personalized medicine has the potential to offer an alternative approach to cancer treatment. Precision medicine, often known as personalized medicine, is a new cancer treatment technique that focuses on tailoring medication to each patient's specific genetic, biochemical, and lifestyle factors. The goal is to optimize tumor response while minimizing therapy side effects, resulting in improved patient care and quality of life. Personalized medicine allows for the creation of focused medicines that address specific gene mutations by leveraging knowledge about a patient's cancer, including its genetic makeup. Ongoing research seeks to detect gene modifications in diverse cancer types, produce novel diagnostic tools, and develop treatments that particularly target these genetic changes. In recent years, personalized medicine has achieved major advances in the treatment of solid tumors, with the promise to improve treatment precision, reduce side effects, as well as enhance outcomes for patients in cancer therapy. This review aims to objectively evaluate the transformation of cancer treatment, emphasizing the shift towards a more precise methodology.

27 May 2024 in Biotechnology for Sustainable Materials
Verified
Journal Article
Open access
PDF file
SVSunil Kumar Verma
Sunil Kumar Verma
PKPrashant Kumar
Prashant Kumar
AMAnshu Mishra
Anshu Mishra
RKRenu Khare
Renu Khare
DSDevendra Singh
Devendra Singh
The use of bio-based nanoparticles in agriculture has gained significant attention due to their potential to enhance plant development, growth, and differentiation. This review aims to provide a comprehensive overview of the impact of bio-based nanoparticles on plant physiology. In this review paper, the various types of bio-based nanoparticles, including cellulose, chitosan, and lignin nanoparticles, and their effects on plant growth and development were discussed. The mechanisms by which these nanoparticles interact with plants at the cellular and molecular levels were also examined. Furthermore, the potential applications of bio-based nanoparticles in agriculture, such as improving nutrient uptake, enhancing stress tolerance, and promoting sustainable crop production, are also highlighted. Overall, this review provides valuable insights into the potential benefits of utilizing bio-based nanoparticles for enhancing plant growth and development while also considering their potential environmental impacts. Graphical Abstract

5 July 2025 in Cancer Pathogenesis and Therapy
Verified
Journal Article
Open access
VDVivek Kumar Dhiman
Vivek Kumar Dhiman
MKManju Kumari
Manju Kumari
DSDevendra Singh
Devendra Singh
Despite significant advances in cancer diagnosis and therapy, the global burden of cancer continues to escalate, characterized by increasing incidence and mortality rates. A problem for successful treatment is chemoresistance, which undermines the effectiveness of traditional and targeted treatments. This review synthesizes emerging therapeutic strategies, including targeted agents, combinatorial regimens, and advances in precision medicine, with a focus on improving clinical outcomes. Integrating the latest understanding from molecular biology, genomics, and pharmacology emphasizes new paths to overcoming resistance. Particular attention is focused on the roles played by exosomes, metabolic reprogramming, and the tumour microenvironment in facilitating drug resistance, as well as promising approaches to counteract these mechanisms and improve therapeutic responsiveness.

24 June 2024 in Next Nanotechnology
Verified
Journal Article
Open access
DSDevendra Singh
Devendra Singh
ASAvinash Sharma
Avinash Sharma
SVSunil Kumar Verma
Sunil Kumar Verma
HPHimanshu Pandey
Himanshu Pandey
MPMinakshi Pandey
Minakshi Pandey

1 June 2023 in Journal of Agriculture and Food Research
Verified
Journal Article
Open access
PKPriyanka Kashyap
Priyanka Kashyap
PSPoonam Shirkot
Poonam Shirkot
RDRatan Das
Ratan Das
HPHimanshu Pandey
Himanshu Pandey
DSDevendra Singh
Devendra Singh