Scientific workflows consist of numerous tasks subject to constraints on data dependency. Effective workflow scheduling is perpetually necessary to efficiently utilize the provided resources to minimize workflow execution cost and time (makespan). Accordingly, cloud computing has emerged as a promising platform for scheduling scientific workflows. In this paper, level- and hierarchy-based scheduling approaches were proposed to address the problem of scheduling scientific workflow in the cloud. In the level-based approach, tasks are partitioned into a set of isolated groups in which available virtual machines (VMs) compete to execute the groups’ tasks. Accordingly, based on a utility function, a task will be assigned to the VM that will achieve the highest utility by executing this task. The hierarchy-based approach employs a look-ahead approach, in which the partitioning of the workflow tasks is performed by considering the entire structure of the workflow, whereby the objective is to reduce the data dependency between the obtained groups. Additionally, in the hierarchy-based approach, a fair-share strategy is employed to determine the share (number of VMs) that will be assigned to each group of tasks. Dividing the available VMs based on the computational requirements of the task groups provides the hierarchy-based approach the advantage of further utilizing the VMs usage. The results show that, on average, both approaches improve the execution time and cost by 27% compared to the benchmarked algorithms.