Land use is a process that turns a piece of land’s natural ecosystem into an artificial one. The mix of plant and man-made covers on the Earth’s surface is known as land cover. Land use is the primary external force behind change in land cover, and land cover has an impact on how land use is carried out, resulting in a synergistic interaction between the two at the Earth’s surface. In China’s Shandong Peninsula city cluster, Dongying is a significant coastal port city. It serves as the administrative hub for the Yellow River Delta and is situated in Shandong Province, China’s northeast. The changes in its urban land use and land cover in the future are crucial to understanding. This research suggests a prediction approach that combines a patch-generation land use simulation (PLUS) model and long-term short-term memory (LSTM) deep learning algorithm to increase the accuracy of predictions of future land use and land cover. The effectiveness of the new method is demonstrated by the fact that the average inaccuracy of simulating any sort of land use in 2020 is around 5.34%. From 2020 to 2030, 361.41 km² of construction land is converted to cropland, and 424.11 km² of cropland is converted to water. The conversion areas between water and unused land and cropland are 211.47 km² and 148.42 km², respectively. The area of construction land and cropland will decrease by 8.38% and 3.64%, respectively, while the area of unused land, water, and grassland will increase by 5.53%, 2.44%, and 0.78%, respectively.