Candice McBain

Candice McBain

Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia
orcid

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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29 September 2020 in Quality of Life Research
Verified
Journal Article
Open access
PDF file
JCJenny Cleland
Jenny Cleland
Claire HutchinsonClaire Hutchinson
Claire Hutchinson
CMCandice McBain
Candice McBain
RWRuth Walker
Ruth Walker
RMRachel Milte
Rachel Milte
JRJulie Ratcliffe
Julie Ratcliffe
Purpose: To identify the salient quality of life characteristics relevant to older people in receipt of community aged care services in order to develop dimensions for a draft descriptive system for a new preference-based quality of life instrument. Methods: Forty-one in-depth semi-structured interviews were undertaken with older people (65 years and over) receiving community aged care services across three Australian states to explore quality of life characteristics of importance to them. The data were analysed using framework analysis to extract broader themes which were organised into a conceptual framework. The data were then summarised into a thematic chart to develop a framework matrix which was used to interpret and synthesise the data. Care was taken throughout to retain the language that older people had adopted during the interviews to ensure that appropriate language was used when identifying and developing the quality of life dimensions. Results: The analysis resulted in the identification of five salient quality of life dimensions: independence, social connections, emotional well-being, mobility, and activities. Conclusion: This research finds that quality of life for older people accessing aged care services goes beyond health-related quality of life and incorporates broader aspects that transcend health. The findings represent the first stage in a multiphase project working in partnership with older people to develop a new preference-based instrument of quality of life for informing quality assessment and economic evaluation in community aged care. In future work, draft items will be developed from these dimensions and tested in face validity interviews before progressing to further psychometric testing.

17 October 2022 in Journal of Aging & Social Policy
Verified
Journal Article
Closed access
Claire HutchinsonClaire Hutchinson
Claire Hutchinson
JCJenny Cleland
Jenny Cleland
CMCandice McBain
Candice McBain
RWRuth Walker
Ruth Walker
RMRachel Milte
Rachel Milte
JRJulie Ratcliffe
Julie Ratcliffe
Quality of life is a critically important outcome measure in aged care. However, few studies have provided a detailed examination of what quality of life means to older adults living in residential care. In the current study, N = 43 older adults (67 to 99 years) living in six residential aged care facilities in four Australian states took part in semi-structured interviews. Participants had normal cognition through to mild /moderate cognitive impairment as measured by the PAS-Cog, were able to provide informed consent, and could participate in an interview conducted in English. Interviews were transcribed, and data was analyzed in NVivo using thematic analysis. Both physical and psycho-social aspects were identified as important for older adults’ quality of life with six key quality of life domains identified: independence, mobility, pain management, social connections, emotional well-being, and activities. More research is needed to test these domains with a more diverse sample of older adults living in residential aged care, in particular older adults from culturally and linguistically diverse communities. Such qualitative work is essential for the development of suitable quality of life measures for this population and provides valuable information to inform improvements to care practices and service provision. Some ways in which the identified quality of life domains could be used to enhance care provision are discussed.

17 September 2024 in Journal of Neurotrauma
Verified
Journal Article
Closed access
Yan LiYan Li
Yan Li
YHYule Hu
Yule Hu
IPIlaria Pozzato
Ilaria Pozzato
MAMohit Arora
Mohit Arora
JSJacob Schoffl
Jacob Schoffl
ACAshley Craig
Ashley Craig
Cognitive impairment is a common complication following spinal cord injury (SCI) and imposes a significant negative impact on adjustment, functional independence, physical and mental health, and quality of life. It is unclear whether interventions for cognitive impairment following SCI are effective. A systematic review of controlled trials was performed to evaluate the effect of interventions on cognitive functions in adults with SCI using search engines: Embase, The Cochrane Library, MEDLINE, Scopus, CINAHL, and Web of Science up to December 2023. Two reviewers independently screened the articles, and study findings were synthesized and summarized. The risk of bias was evaluated using the Cochrane Risk of Bias 2.0 tool. Eight moderate-quality studies were found that investigated the effects of physical exercise/activity-based therapy plus cognitive training or intermittent hypoxia, diet modification and dietary supplements, tibial nerve or cortical stimulation, and drug therapy on cognitive function in SCI. Physical exercise/activity–based therapy plus cognitive training showed most promise for improving cognitive functions, while drug therapy, diet modification, and dietary supplements showed potential for improving cognitive function. However, about half of the participants experienced heightened instability in blood pressure following the administration of midodrine, and one participant reported gastrointestinal side effects after taking omega-3 fatty acids. There was no evidence of improvement in cognitive function for stimulation techniques. The current review highlights the scarcity of research investigating the effectiveness of interventions that target cognitive function after SCI. Further, the effects of these eight studies are uncertain due to concerns about the quality of designs and small sample sizes utilized in the trials, as well as the employment of insensitive neurocognitive tests when applied to adults with SCI. This review highlights a significant gap in knowledge related to SCI cognitive rehabilitation.

15 February 2023 in Quality in Ageing and Older Adults
Verified
Journal Article
Closed access
JCJenny Cleland
Jenny Cleland
Claire HutchinsonClaire Hutchinson
Claire Hutchinson
CMCandice McBain
Candice McBain
JKJyoti Khadka
Jyoti Khadka
RMRachel Milte
Rachel Milte
JRJulie Ratcliffe
Julie Ratcliffe
This paper aims to assess the face validity to inform content validity of the Quality of Life – Aged Care Consumers (QOL-ACC), a new measure for quality assessment and economic evaluation in aged care. Semi-structured interviews were conducted with older adults (66–100 years) receiving aged care services at home (n = 31) and in residential care (n = 28). Participants provided feedback on draft items to take forward to the next stage of psychometric assessment. Items were removed according to several decision criteria: ambiguity, sensitive wording, not easy to answer and/or least preferred by participants. The initial candidate set was reduced from 34 items to 15 items to include in the next stage of the QOL-ACC development alongside the preferred response category. The reduced set reflected the views of older adults, increasing the measure’s acceptability, reliability and relevance. Quality of life is a key person-centred quality indicator recommended by the recent Royal Commission into Aged Care Quality and Safety. Responding to this policy reform objective, this study documents a key stage in the development of the QOL-ACC measure, a new measure designed to assess aged care specific quality of life.

Verified
Journal Article
Open access
PDF file
MAMohit Arora
Mohit Arora
IPIlaria Pozzato
Ilaria Pozzato
CMCandice McBain
Candice McBain
Yvonne TranYvonne Tran
Yvonne Tran
DSDanielle Sandalic
Danielle Sandalic
ACAshley Craig
Ashley Craig
Background: Mild cognitive impairment (MCI) is a common secondary condition associated with spinal cord injury (SCI). Cognitive reserve (CR) is believed to protect against cognitive decline and can be assessed by premorbid intelligence (pmIQ). Despite the potential utility of pmIQ as a complementary metric in the evaluation of MCI in SCI, this approach has been infrequently employed. The purpose of this study was to examine the association between MCI and pmIQ in adults with SCI with the aim of exploring the potential value of pmIQ as a marker of CR in this population. Methods: Cognitive function was assessed on three occasions in adults with SCI over a 12-month period post-injury, and pmIQ was assessed once at baseline. Demographic and mental health measures were also collected, and logistic regression was conducted to determine the strength of association between pmIQ and MCI while adjusting for factors such as mental health and age. Results: The regression analysis revealed that at the time of admission to SCI rehabilitation, the MCI assessed by a valid neurocognitive screen was strongly associated with pmIQ. That is, if a person has MCI, there was 5.4 greater odds (p < 0.01) that they will have poor pmIQ compared to a person without MCI after adjustment for age and mental health. Conclusions: The assessment of CR is an important area that should be considered to improve the process of diagnosing MCI in adults with an acute SCI and potentially facilitate earlier intervention to slow or prevent cognitive decline.

6 January 2025 in Journal of Affective Disorders
Verified
Journal Article
Open access
IPIlaria Pozzato
Ilaria Pozzato
JSJacob Schoffl
Jacob Schoffl
Yvonne TranYvonne Tran
Yvonne Tran
MAMohit Arora
Mohit Arora
CMCandice McBain
Candice McBain
ACAshley Craig
Ashley Craig
Traumatic physical injuries can lead to psychological distress and increased risk of psychiatric disorders, often reflected in dysregulated autonomic responses measurable through heart rate variability (HRV). Slow-paced breathing has shown potential in enhancing HRV, but its effectiveness in injured survivors remains unexplored. This study investigates the effect of slow-paced breathing on HRV among injured survivors compared to non-injured individuals and explores the influence of psychological distress and spontaneous respiratory rate on this effect. The study involved 120 injured individuals and 112 non-injured controls with similar age, sex, and education levels. Injured participants with minor-to-moderate injuries from traffic crashes were assessed 3-6 weeks post-injury. Psychological distress was defined as the risk of post-traumatic stress disorder and/or major depression. Physiological assessment (HRV) included a 2-min resting baseline and a 2-min slow-paced breathing session (6 breaths/min). Repeated measure MANCOVA assessed HRV changes between groups, while correlation analyses examined the relationship between these changes. Injured survivors had significantly lower HRV than non-injured controls. Both groups showed notable HRV increases during slow-paced breathing. Among injured individuals, those with higher psychological distress exhibited greater HRV increases, particularly in parasympathetic activity and overall variability. Higher spontaneous respiratory rates were associated with greater HRV changes, especially in non-injured individuals. Slow-paced breathing demonstrated significant physiological effects for injured survivors, particularly those with higher psychological distress, and supports its potential in improving stress regulation post-injury. Future research should examine the long-term effects of sustained breathing practice and clinical applicability in reducing psychological distress and disability post-injury.