Mayara Santana dos Santos

Prof. Mayara Santana dos Santos

orcid
PhD candidate in Biochemistry and Molecular Biology in the F...

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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29 March 2023 in Molecules
Verified
Journal Article
Open access
PDF file
SFSérgio Antunes Filho
Sérgio Antunes Filho
Mayara Santana dos SantosMayara Santana dos Santos
Mayara Santana dos Santos
OSOtávio Augusto Leitão dos Santos
Otávio Augusto Leitão dos Santos
BBBianca Pizzorno Backx
Bianca Pizzorno Backx
MSMaria-Loredana Soran
Maria-Loredana Soran
MBMohamed Bououdina
Mohamed Bououdina
Plant extracts and essential oils have a wide variety of molecules with potential application in different fields such as medicine, the food industry, and cosmetics. Furthermore, these plant derivatives are widely interested in human and animal health, including potent antitumor, antifungal, anti-inflammatory, and bactericidal activity. Given this diversity, different methodologies were needed to optimize the extraction, purification, and characterization of each class of biomolecules. In addition, these plant products can still be used in the synthesis of nanomaterials to reduce the undesirable effects of conventional synthesis routes based on hazardous/toxic chemical reagents and associate the properties of nanomaterials with those present in extracts and essential oils. Vegetable oils and extracts are chemically complex, and although they are already used in the synthesis of nanomaterials, limited studies have examined which molecules are effectively acting in the synthesis and stabilization of these nanostructures. Similarly, few studies have investigated whether the molecules coating the nanomaterials derived from these extracts and essential oils would bring benefits or somehow reduce their potential activity. This synergistic effect presents a promising field to be further explored. Thus, in this review article, we conducted a comprehensive review addressing the main groups of molecules present in plant extracts and essential oils, their extraction capacity, and available methodologies for their characterization. Moreover, we highlighted the potential of these plant products in the synthesis of different metallic nanomaterials and their antimicrobial capacity. Furthermore, we correlated the extract’s role in antimicrobial activity, considering the potential synergy between molecules from the plant product and the different metallic forms associated with nanomaterials.

1 May 2021 in Current Pharmaceutical Biotechnology
Verified
Journal Article
Closed access
PDF file
BBBianca Pizzorno Backx
Bianca Pizzorno Backx
Mayara Santana dos SantosMayara Santana dos Santos
Mayara Santana dos Santos
OSOtávio Augusto Leitão dos Santos
Otávio Augusto Leitão dos Santos
SFSérgio Antunes Filho
Sérgio Antunes Filho
Nanotechnology is an area of science in which new materials are developed. The correlation between nanotechnology and microbiology is essential for the development of new drugs and vaccines. The main advantage of combining these areas is to associate the latest technology in order to obtain new ways for solving problems related to microorganisms. This review seeks to investigate nanoparticle formation's antimicrobial properties, primarily when connected to the green synthesis of silver nanoparticles. The development of new sustainable methods for nanoparticle production has been instrumental in designing alternative, non-toxic, energy-friendly, and environmentally friendly routes. In this sense, it is necessary to study silver nanoparticles' green synthesis concerning their antimicrobial properties. Antimicrobial silver nanoparticles' mechanisms demonstrate efficiency to gram-positive bacteria, gram-negative bacteria, fungi, viruses, and parasites. However, attention is needed with the emergence of resistance to these antimicrobials. This article seeks to relate the parameters of green silver- based nanosystems with the efficiency of antimicrobial activity.

19 February 2026 in Plants
Verified
Journal Article
Open access
PDF file
Mayara Santana dos SantosMayara Santana dos Santos
Mayara Santana dos Santos
SRSilas Pessini Rodrigues
Silas Pessini Rodrigues
AHAdriana Hemerly
Adriana Hemerly
AFAntonio Alberto Ribeiro Fernandes
Antonio Alberto Ribeiro Fernandes
PFPATRICIA FERNANDES
PATRICIA FERNANDES
Climate change has intensified the occurrence of biotic and abiotic stresses, representing a major threat to agricultural productivity. This climate variability, coupled with the excessive use of agrochemicals, not only compromises environmental sustainability but also exacerbates food insecurity, directly affecting food availability and quality. In this context, biotechnological strategies have proven essential for mitigating the effects of stress on plants, promoting practices focused on agricultural sustainability. Notable among these strategies is the use of plant growth-promoting microorganisms, which are emerging as promising alternatives capable of improving plant tolerance to stress conditions and simultaneously reducing dependence on agrochemicals. These microorganisms can act as nitrogen fixers and solubilizers of nutrients, such as phosphorus and potassium. Additionally, they can influence plant immune responses by inducing systemic resistance and promoting the synthesis of phytohormones, such as auxins, cytokinins, and abscisic acid, which support plant development during the stress response. The interaction between plants and microorganisms represents a sustainable agricultural management strategy capable of enhancing crop tolerance to environmental adversities. In this review, we discuss the microorganisms known to establish beneficial interactions with plants, leading to improved performance under biotic and abiotic stress. Overall, this work highlights the potential of plant–microbe partnerships as a cornerstone for advancing sustainable agriculture in the face of global challenges.

12 February 2023 in Life
Verified
Journal Article
Open access
PDF file
Mayara Santana dos SantosMayara Santana dos Santos
Mayara Santana dos Santos
SFSérgio Antunes Filho
Sérgio Antunes Filho
BBBianca Pizzorno Backx
Bianca Pizzorno Backx
Healthy eating habits are one of the requirements for the health of society. In particular, in natura foods are increasingly encouraged, since they have a high concentration of nutrients. However, these foods are often grown in the presence of agrochemicals, such as fertilizers and pesticides. To increase crop productivity and achieve high vigor standards in less time, farmers make excessive use of agrochemicals that generate various economic, environmental, and clinical problems. In this way, bionanotechnology appears as an ally in developing technologies to improve planting conditions, ranging from the health of farmers and consumers to the production of new foods and functional foods. All these improvements are based on the better use of land use in synergy with the lowest generation of environmental impacts and the health of living beings, with a view to the study and production of technologies that take into account the concept of One Health in its processes and products. In this review article, we will address how caring for agriculture can directly influence the quality of the most desired foods in contemporary society, and how new alternatives based on nanotechnology can point to efficient and safe solutions for living beings on our planet.

16 September 2020 in ACTA Apicola Brasilica
Verified
Journal Article
Open access
PDF file
Mayara Santana dos SantosMayara Santana dos Santos
Mayara Santana dos Santos
BBBianca Pizzorno Backx
Bianca Pizzorno Backx
A própolis é um material resinoso de composição peculiar que estimula variados questionamentos desde as civilizações antigas. Essas indagações estão relacionadas às diferentes propriedades associadas à própolis, como as atividades antioxidantes, antimicrobianas, antivirais, antimutagênicas, anti-inflamatórias, cicatrizantes, dentre outras. Desta forma, essas propriedades presentes na própolis estão sendo empregadas em produtos bionanotecnológicos por conta, por exemplo, do seu alto teor de flavonoides e substâncias fenólicas que atuam em sinergia com as propriedades encontradas nas nanopartículas de prata. Neste artigo, diferentes fatores físico-químicos que podem influenciar a estabilidade das nanopartículas de prata dispersas na própolis serão discutidos. As caracterizações por espectrofotometria no ultravioleta e visível definem a estabilidade do nanossistema coloidal.