Antonella Lesin

Dr. Antonella Lesin


Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 April 2023 in Nutrients
Verified
Journal Article
Open access
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Dinko MartinovicDinko Martinovic
Dinko Martinovic
DTDaria Tokic
Daria Tokic
EPEma Puizina
Ema Puizina
MUMislav Ušljebrka
Mislav Ušljebrka
SKSanja Kadić
Sanja Kadić
Josko BozicJosko Bozic
Josko Bozic
While surgical therapy for head and neck cancer (HNC) is showing improvement with the advancement of reconstruction techniques, the focus in these patients should also be shifting to supportive pre and aftercare. Due to the highly sensitive and anatomically complex region, these patients tend to exhibit malnutrition, which has a substantial impact on their recovery and quality of life. The complications and symptoms of both the disease and the therapy usually make these patients unable to orally intake food, hence, a strategy should be prepared for their nutritional management. Even though there are several possible nutritional modalities that can be administrated, these patients commonly have a functional gastrointestinal tract, and enteral nutrition is indicated over the parenteral option. However, after extensive research of the available literature, it seems that there is a limited number of studies that focus on this important issue. Furthermore, there are no recommendations or guidelines regarding the nutritional management of HNC patients, pre- or post-operatively. Henceforth, this narrative review summarizes the nutritional challenges and management modalities in this particular group of patients. Nonetheless, this issue should be addressed in future studies and an algorithm should be established for better nutritional care of these patients.

4 January 2023 in Life
Verified
Journal Article
Open access
PDF file
Dinko MartinovicDinko Martinovic
Dinko Martinovic
DTDaria Tokic
Daria Tokic
EPEma Puizina
Ema Puizina
SKSanja Kadić
Sanja Kadić
ALAntonella Lesin
Antonella Lesin
Josko BozicJosko Bozic
Josko Bozic
Obstructive sleep apnea (OSA) is a chronic, sleep-related breathing disorder. It is characterized by a nocturnal periodic decrease or complete stop in airflow due to partial or total collapse of the oropharyngeal tract. Surgical treatment of OSA is constantly evolving and improving, especially with the implementation of new technologies, and this is needed because of the very heterogeneous reasons for OSA due to the multiple sites of potential airway obstruction. Moreover, all of these surgical methods have advantages and disadvantages; hence, patients should be approached individually, and surgical therapies should be chosen carefully. Furthermore, while it is well-established that oromaxillofacial surgery (OMFS) provides various surgical modalities for treating OSA both in adults and children, a new aspect is emerging regarding the possibility that some of the surgeries from the OMFS domain are also causing OSA. The latest studies are suggesting that surgical treatment in the head and neck region for causes other than OSA could possibly have a major impact on the emergence of newly developed OSA, and this issue is still very scarcely mentioned in the literature. Both oncology, traumatology, and orthognathic surgeries could be potential risk factors for developing OSA. This is an important subject, and this review will focus on both the possibilities of OMFS treatments for OSA and on the OMFS treatments for other causes that could possibly be triggering OSA.

11 August 2023 in Healthcare
Verified
Journal Article
Open access
PDF file
ISIvan Frka Separovic
Ivan Frka Separovic
Dinko MartinovicDinko Martinovic
Dinko Martinovic
ALAntonella Lesin
Antonella Lesin
EPEma Puizina
Ema Puizina
DTDaria Tokic
Daria Tokic
Josko BozicJosko Bozic
Josko Bozic
This study aimed to examine the frequency of temporomandibular disorder among biomedical students and relate its occurrence to lifestyle habits. A cross-sectional collection of data was carried out and included a total of 676 examinees through a questionnaire that had 73 questions: general information and lifestyle habits, the Fonseca Anamnestic index (FAI), the Jaw Function Limitation Scale (JFLS), and the Perceived Stress Questionnaire (PSQ). The statistical analyses between three or more groups were conducted using the one-way analysis of variance (ANOVA) with post hoc Scheffé test or Kruskal–Wallis test with post hoc Dunn’s test for quantitative variables. The comparison of qualitative variables was conducted using the Chi-square test, while the correlations were determined using Spearman’s correlation test. The analysis showed that a higher frequency of moderate or severe TMD was observed in subjects who were smokers (p < 0.001) compared to non-smokers. Subjects who consumed more coffee had moderate to severe TMD compared to subjects who consumed a lesser amount (p < 0.001). Furthermore, a positive correlation between the amount of stress and the severity of TMD was found. Our study implies that students of biomedical studies have an increased risk for TMD and that there is a link with their lifestyle habits.

26 March 2025 in Medicina
Verified
Journal Article
Open access
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Dinko MartinovicDinko Martinovic
Dinko Martinovic
MCMatea Cernak
Matea Cernak
SLSlaven Lasić
Slaven Lasić
EPEma Puizina
Ema Puizina
ALAntonella Lesin
Antonella Lesin
Josko BozicJosko Bozic
Josko Bozic
Background and Objectives: Oral health is a critical component of overall well-being, and it is highly influenced by psychological factors. While mental health disorders are often associated with poor oral health, the impact of obsessive–compulsive personality disorder (OCPD) tendencies on oral hygiene behaviors remains underexplored. This study aimed to investigate the relationship between OCPD tendencies and oral health behaviors among biomedical students. Materials and Methods: A cross-sectional survey was conducted among 384 biomedical students aged 18–30 years. Participants completed the Hiroshima University Dental Behavior Inventory (HU-DBI) to assess oral health behaviors and the Five Factor Obsessive–Compulsive Inventory—Short Form (FFOCI-SF) to evaluate OCPD tendencies, and they were divided into high and low tendencies groups. Sociodemographic data were also collected. Statistical analysis of all collected data was performed using the MedCalc computer software for Windows®. Results: The higher OCPD tendencies group was older (p = 0.003), with predominantly female students (p = 0.005), and with higher academic grades (p < 0.001). These participants exhibited significantly better HU-DBI total scores compared to the group with the lower tendencies (8.0 (7.0–8.0) vs. 7.0 (6.0–8.0); p < 0.001). Traits such as perfectionism, fastidiousness, and punctiliousness were significantly associated with better oral hygiene practices (p < 0.001). Conclusions: Our results suggest that OCPD tendencies in biomedical students positively influence oral health behaviors through traits like perfectionism and attention to detail, though excessive rigidity may pose risks such as over-brushing. However, future longitudinal larger-scale studies need to address these findings.

15 March 2023 in Acta Stomatologica Croatica
Verified
Journal Article
Open access
DJDaniel Jerković
Daniel Jerković
KJKristian Jerković
Kristian Jerković
ALAntonella Lesin
Antonella Lesin
APAna Poljičanin
Ana Poljičanin
IGIvan Galic
Ivan Galic
This is the first case report where two patients were under uniform denosumab administration protocol in diffuse sclerosing osteomyelitis (DSO) treatment and were closely monitored for 18 months. Objectives: This study aimed to describe the beneficial effects of denosumab in DSO treatment as well as pain relief and the significant lack of long-term use due to poorer outcomes after repeated use. DSO of the jaw is a poorly understood rare chronic disease the treatment of which is still very challenging despite a rapid development of medicine. Different medical treatments have been proposed without any significant long-lasting success. Bisphosphonates have offered substantial clinical benefit in DSO therapy, but due to harmful pharmacodynamic properties, denosumab therapy has been used to replace bisphosphonate therapy. Patients had a reduction in pain intensity with each subsequent application of denosumab but with less success than the first administration of denosumab. This case report has shown that denosumab could be a promising conservative treatment option for pain treatment in patients suffering from DSO.

11 October 2022 in European Journal of Dentistry
Verified
Journal Article
Open access
PDF file
ALAntonella Lesin
Antonella Lesin
IGIvan Galic
Ivan Galic
ATAntonija Tadin
Antonija Tadin
KVKatarina Vilović
Katarina Vilović
DJDaniel Jerković
Daniel Jerković
Dentigerous cysts are rarely reported in young children. They are usually asymptomatic and only identified when becoming significantly large. Treatment by enucleation may damage structures like the inferior alveolar nerve, maxillary sinus, or permanent teeth, thus reducing the child's quality of life. Therefore, conservative surgical treatment such as decompression is indicated. This case report describes the treatment and subsequent complete regression of an inflammatory dentigerous cyst based on the decompression method using a customized surgical tube in a 10-year-old girl. The innervation was preserved, and permanent teeth erupted.