Phenolic compounds have a positive effect on obesity, diabetes, and cardiovascular diseases because of their antioxidant and anti-inflammatory capacity. The prevalence of these diseases has increased in the last years in the Mexican population. Therefore, the Mexican diet must be assessed as provider of phenolic compounds. To assess this, a survey of phenolic compound intake was validated and applicated to 973 adults (798 females) between 18 and 79 years old. We compared the phenolic compound intake of 324 participants with more diseases (239 females) and 649 participants with healthier condition (559 females). The groups differed in sex, age, and scholarship. Males, older participants, and those with lower schooling reported suffering from more diseases. Regarding phenolic compound intake analyses, the participants with healthier conditions displayed a higher phenolic compound intake than the other group in all foods assessed. In addition, the regression model showed that the phenolic compounds intake of Mexican dishes, such as arroz con frijol or enchiladas, positively affected health status, suggesting that this traditional food is beneficial for the participant’s health condition. However, the weight effect of PCI was different for each disease. We conclude that, although PCI of Mexican food positively affects health conditions, this effect depends on sex, age, and participants’ diseases.

* Variable dependiente: nivel de inseguridad alimentaria; variables predictoras destacadas como significativas: grado de estudios, P1-P6 (preguntas complementarias anexadas a la Escala Latinoamericana y Caribeña de Seguridad Alimentaria, referentes a la frecuencia en la ausencia de la toma de alimentos, causas principales de ausencia de toma de alimentos, variedad y frecuencia de alimentos consumidos, frecuencia de ingesta de alimentos ultraprocesados, tiempos de comidas omitidos, percepción de la alimentación actual e ideal y conocimientos básicos en materia de alimentación y nutrición). CIA: