Jorge Mancini Mancini-Filho

Prof. Dr. Jorge Mancini Mancini-Filho


Research Focus & Metrics

Academic Career Length

29Years (1998-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 August 1998 in Brazilian Journal of Medical and Biological Research
Verified
Journal Article
Open access
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MMM.S. Miranda
M.S. Miranda
RCR.G. Cintra
R.G. Cintra
SBS.B.M. Barros
S.B.M. Barros
JMJorge Mancini Mancini-Filho
Jorge Mancini Mancini-Filho
Spirulina maxima, which is used as a food additive, is a microalga rich in protein and other essential nutrients. Spirulina contains phenolic acids, tocopherols and ß-carotene which are known to exhibit antioxidant properties. The aim of the present study was to evaluate the antioxidant capacity of a Spirulina extract. The antioxidant activity of a methanolic extract of Spirulina was determined in vitro and in vivo. The in vitro antioxidant capacity was tested on a brain homogenate incubated with and without the extract at 37oC. The IC50 (concentration which causes a 50% reduction of oxidation) of the extract in this system was 0.18 mg/ml. The in vivo antioxidant capacity was evaluated in plasma and liver of animals receiving a daily dose of 5 mg for 2 and 7 weeks. Plasma antioxidant capacity was measured in brain homogenate incubated for 1 h at 37oC. The production of oxidized compounds in liver after 2 h of incubation at 37oC was measured in terms of thiobarbituric acid reactant substances (TBARS) in control and experimental groups. Upon treatment, the antioxidant capacity of plasma was 71% for the experimental group and 54% for the control group. Data from liver spontaneous peroxidation studies were not significantly different between groups. The amounts of phenolic acids, a-tocopherol and ß-carotene were determined in Spirulina extracts. The results obtained indicate that Spirulina provides some antioxidant protection for both in vitro and in vivo systems.

1 January 2007 in Revista Brasileira de Fruticultura
Verified
Journal Article
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ALAlessandro de Lima
Alessandro de Lima
ASAna Mara de Oliveira e Silva
Ana Mara de Oliveira e Silva
RTReginaldo Almeida Trindade
Reginaldo Almeida Trindade
RTRosângela Pavan Torres
Rosângela Pavan Torres
JMJorge Mancini Mancini-Filho
Jorge Mancini Mancini-Filho
O conhecimento da composição química dos alimentos é fundamental para se avaliarem a disponibilidade de nutrientes e o seu consumo por populações. Neste trabalho, o pequi (Caryocar brasiliense, Camb.) foi caracterizado pela composição centesimal e pela presença de compostos bioativos na polpa e na amêndoa. Os dados do perfil lipídico mostram alto teor de lípides tanto na polpa quanto na amêndoa, destacando-se nos mesmos a presença dos ácidos graxos insaturados, predominando o ácido oléico como principal componente entre os ácidos graxos. Foi observada também a relação entre os elevados teores de ácidos graxos insaturados com os compostos fenólicos e carotenóides presentes, tendo a polpa quantidades mais expressivas dessas substâncias quando comparada à amêndoa, além de conter uma quantidade superior de fibra alimentar. Os resultados obtidos abrem a perspectiva de se utilizar o pequi como fruto que apresenta, na sua composição, compostos importantes para a formulação de uma dieta saudável.

1 January 2013 in Nutrition & Metabolism
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Journal Article
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MAMilessa S Afonso
Milessa S Afonso
ASAna Mara de O Silva
Ana Mara de O Silva
ECEliane Bt Carvalho
Eliane Bt Carvalho
DRDiogo P Rivelli
Diogo P Rivelli
SBSílvia Bm Barros
Sílvia Bm Barros
JMJorge Mancini Mancini-Filho
Jorge Mancini Mancini-Filho
Phenolic compounds combine antioxidant and hypocholesterolemic activities and, consequently, are expected to prevent or minimize cardiometabolic risk.

1 September 2015 in Food Science and Technology
Verified
Journal Article
Open access
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FSFernanda Branco Shinagawa
Fernanda Branco Shinagawa
FSFernanda Carvalho de Santana
Fernanda Carvalho de Santana
LTLucillia Rabelo Oliveira Torres
Lucillia Rabelo Oliveira Torres
JMJorge Mancini Mancini-Filho
Jorge Mancini Mancini-Filho
Grape seed oil (GSO) is not often consumed in Brazil and little is known of its nutritional value. Around the world there are already studies that point to the high levels of minority bioactive compounds and their relation to health benefits. The main constituent of GSO is linoleic fatty acid, some works are controversial and there is no consensus in literature regarding their effect on the animal organism. Thus, this study aimed to present a review of GSO and show the potential health effects of its major components, not only linoleic acid, but also γ-tocotrienol and β-sitosterol, and finally, their influence on lipid-modulating, anti and pro oxidative parameters.

26 February 2016 in Food Science and Technology
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Journal Article
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IMIllana Louise Pereira de Melo
Illana Louise Pereira de Melo
ECEliane Bonifácio Teixeira de Carvalho
Eliane Bonifácio Teixeira de Carvalho
ASAna Mara de Oliveira e Silva
Ana Mara de Oliveira e Silva
LYLuciana Tedesco Yoshime
Luciana Tedesco Yoshime
JSJosé Augusto Gasparotto Sattler
José Augusto Gasparotto Sattler
JMJorge Mancini Mancini-Filho
Jorge Mancini Mancini-Filho
This study aimed to characterize pomegranate seed oil and evaluate its quality and stability parameters against those of linseed oil. The profile of fatty acids and phytosterols and the content of tocopherols were analyzed by gas chromatography and high performance liquid chromatography, respectively. The quality of both oils was assessed as recommended by the American Oil Chemists' Society (AOCS) and stability was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH), β-carotene bleaching (coupled oxidation of β-carotene/linoleic acid) and Rancimat® assays. While α-linolenic acid (52%) was the most abundant fatty acid in linseed oil (LO), punicic acid (55%) was highest in pomegranate seed oil (PSO). Tocopherols and phytosterols (175 and 539 mg/100 g, respectively) were greater in PSO than in LO (51 and 328 mg/100 g, respectively). Both oils met quality standards. The β-carotene bleaching and the DPPH assays showed greater oxidative stability for PSO than for LO. The Rancimat® method, on the other hand, indicated low stability for both oils.

29 October 2015 in Journal of Food Science
Verified
Journal Article
Closed access
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FSFernanda Carvalho de Santana
Fernanda Carvalho de Santana
FSFernanda Branco Shinagawa
Fernanda Branco Shinagawa
EAElias da Silva Araujo
Elias da Silva Araujo
ACAna Maria Costa
Ana Maria Costa
JMJorge Mancini Mancini-Filho
Jorge Mancini Mancini-Filho