Dr. Vasilyeva Irina Anatol'evna

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Academic Career Length

19Years (2008-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 April 2022 in Tuberculosis and Lung Diseases

Journal Article

Tuberculosis Situation in the Years of the COVID-19 Pandemic – 2020-2021

Vasilyeva Irina Anatol'evna

V. V. Testov

Sergey Aleksandrovich Sterlikov

The article presents the analysis of changes in preliminary and estimated epidemiological rates: tuberculosis (TB) incidence, TB mortality, and clinical and social structure of new TB cases. It has been found that against the background of continuing improvement of the epidemic situation (reduction of TB incidence and mortality), the clinical structure of TB cases detected in 2020-2021 deteriorated compared to 2015-2019 which was manifested by higher frequency of pulmonary tissue destruction, massive bacterial excretion (by smear), and fibrous cavernous pulmonary TB. The number of TB cases detected post mortem has increased, as well as one-year mortality. These changes indicate low detection of TB cases in 2020. Changes in the incidence of TB/HIV co-infection and the number of new cases with bacterial excretion and multiple drug resistant TB essentially repeat the changes in TB incidence in the resident population during this period.

1 January 2017 in Tuberculosis and Lung Diseases

Journal Article

INCIDENCE, MORTALITY AND PREVALENCE AS INDICATORS OF TUBERCULOSIS BURDEN IN WHO REGIONS , COUN TRIES OF THE WORLD AND THE RUSSIAN FEDERATION. Part 2. Tuberculosis mortality

Vasilyeva Irina Anatol'evna

Evgeny M. Belilovsky

S. E. Borisov

Sergey Aleksandrovich Sterlikov

ЗАБОЛЕВАЕМОСТЬ, СМЕРТНОСТЬ И РАСПРОСТРАНЕННОСТЬ КАК ПОКАЗАТЕЛИ БРЕМЕНИ ТУБЕРКУЛЕЗА В РЕГИОНАХ ВОЗ, СТРАНАХ МИРА И В РОССИЙСКОЙ ФЕДЕРАЦИИ1 Часть 2. Смертность от туберкулеза

1 June 2017 in Tuberculosis and Lung Diseases

Journal Article

INCIDENCE, MORTALITY AND PREVALENCE AS INDICATORS OF TUBERCULOSIS BURDEN IN WHO REGIONS, COUNTRIES OF THE WORLD AND THE RUSSIAN FEDERATION. PART 1. TUBERCULOSIS INCIDENCE AND PREVALENCE

Research Institute of Phthiopulmonology by I.M. Sechenov First Moscow State Medical University Russian Federation

Vasilyeva Irina Anatol'evna

E. M. Belilovsky

Moscow Municipal Scientific Practical Center For Tuberculosis Control Russian Federation

S. E. Borisov

Central Research Institute for Public Health Organization and Informatization Russian Federation

ЗАБОЛЕВАЕМОСТЬ, СМЕРТНОСТЬ И РАСПРОСТРАНЕННОСТЬ КАК ПОКАЗАТЕЛИ БРЕМЕНИ ТУБЕРКУЛЕЗА В РЕГИОНАХ ВОЗ, СТРАНАХ МИРА И В РОССИЙСКОЙ ФЕДЕРАЦИИ. ЧАСТЬ 1. ЗАБОЛЕВАЕМОСТЬ И РАСПРОСТРАНЕННОСТЬ ТУБЕРКУЛЕЗА

5 May 2023 in Microorganisms

Journal Article

Experimental Studies of the Liposomal Form of Lytic Mycobacteriophage D29 for the Treatment of Tuberculosis Infection

Vadim Vadimovich Avdeev

Victor Vladimirovich Kuzin

Mikhail Александрович Vladimirsky

Vasilyeva Irina Anatol'evna

We have studied the antimycobacterial efficacy of the liposomal preparation of mycobacteriophage D29 on models of tuberculous granuloma in vitro and in the experiment on laboratory mice of the relatively resistant strain C57BL/6, infected with the virulent strain of M. tuberculosis H37Rv. We have shown the preparation of liposomal preparation of the lytic mycobacteriophages and its characteristics. The experiments showed a significant lytic effect of the liposomal form of mycobacteriophage D29 both on the model of tuberculous granuloma formed by human blood mononuclear cells in vitro, which is formed in the presence of Mycobacterium tuberculosis and on the model of tuberculous infection in C57BL/6 mice. Keywords: mycobacteriophage D29, M. tuberculosis, liposomes, tuberculous granuloma in vitro, tuberculosis infection and its treatment.