Amaryllidaceae alkaloids are secondary metabolites with interesting medicinal properties. Almost every Narcissus species can synthesize them and constitute an excellent source for their isolation and study. Several Amaryllidaceae alkaloids have shown acetylcholinesterase inhibitory activities and are a promising tool for treating cholinergic disorders such as Alzheimer’s disease (AD). Indeed, three of the four palliative treatments approved for AD are acetylcholinesterase (AChE) inhibitors and one of them, galanthamine, is an Amaryllidaceae alkaloid itself. This molecule is currently isolated from natural sources. However, its production is insufficient to supply the increasing demand for the active principle. Our main aim is to discover tools to improve galanthamine production and to prospect for potential new and more efficient drugs for AD treatment. Furthermore, we seek to broaden the knowledge of plants of the genus Narcissus from a chemotaxonomic perspective. Hence, in this study, we evaluate the alkaloid content through GC–MS and the AChE inhibitory activity of ten autumn-flowering Narcissus, which have been less studied than their spring-flowering counterparts. A total of thirty Amaryllidaceae alkaloids have been found, twenty-eight properly identified. Two Narcissus contained galanthamine, and seven were able to inhibit AChE.

Erythrolamprus macrosomus (Amaral, 1936) is a snake recently revalidated to the species level, with a known distribution in Argentina, Brazil and Paraguay. We discovered a single specimen in Bolivia from the Department of Cochabamba, that corroborates this species in the country and extends its distribution westward.

We report a new altitudinal record for Bothrops bilineatus (Wied-Neuwied, 1821) in the department of Cochabamba, Bolivia, based on verifiable records from the Yungas ecoregion of the department. This work not only corroborates the highest record for Bolivia, but also extends the record of the species by more than 50 km to the southeast, from the closest record in Villa Tunari, Cochabamba, Bolivia. The first record of the species for the Yungas ecoregion in Bolivia is formally confirmed. The highest record for the species in South America is also confirmed.

Se presentan catorce nuevos registros adicionales obtenidos durante los monitoreos de herpetofauna realizados en Sehuencas, Parque Nacional Carrasco, Cochabamba, Bolivia, entre junio de 2018 y enero de 2024. Anfibios, Bufonidae (Rhinella quechua), Hemiphractidae (Gastrotheca lauzuricae, Gastrotheca testudinea); Hylidae (Boana lanciformis), Phyllomedusidae (Phyllomedusa boliviana) y Craugastoridae (Oreobates sanctaecrucis y Yunganastes pluvicanorus). Reptiles, Colubridae (Chironius exoletus, Chironius laurenti) y Dipsadidae (Erythrolamprus aesculapii, Erythrolamprus cf. reginae, Erythrolamprus taeniurus, Oxyrhopus emberti, Siphlophis compressus). Estos registros constituyen importantes adiciones altitudinales que a su vez demarcan la distribución de algunas especies en los Yungas del Parque Nacional Carrasco, incrementando así el conocimiento y comprensión de la herpetofauna en una de las ecorregiones menos conocidas, como es la ecoregion de los Yungas en Bolivia y Sudamérica.

We report a new altitudinal record for Rhinella kuka Köhler et al., 2023. This species is registered in the departments of Cochabamba and La Paz in Bolivia from 800 and 1650 m asl. In this work we present the lowest record for this endemic species to Bolivia at 307 m asl.