Alexander Kaserer

Dr. Alexander Kaserer

Institute of Anesthesiology, University and University Hospital Zurich, 8091 Zurich, Switzerland
orcid

Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 June 2019 in The Lancet
Verified
Journal Article
Closed access
DSDonat Spahn
Donat Spahn
FSFelix Schoenrath
Felix Schoenrath
GSGabriela H Spahn
Gabriela H Spahn
BSBurkhardt Seifert
Burkhardt Seifert
PSPhilipp Stein
Philipp Stein
VFVolkmar Falk
Volkmar Falk

7 September 2020 in Journal of Medical Internet Research
Verified
Journal Article
Open access
SSSadiq Said
Sadiq Said
MGMalgorzata Gozdzik
Malgorzata Gozdzik
TRTadzio R. Roche
Tadzio R. Roche
JBJulia Braun
Julia Braun
JRJulian Rössler
Julian Rössler
David Werner TschollDavid Werner Tscholl
David Werner Tscholl
Background: Patient monitoring is indispensable in any operating room to follow the patient’s current health state based on measured physiological parameters. Reducing workload helps to free cognitive resources and thus influences human performance, which ultimately improves the quality of care. Among the many methods available to assess perceived workload, the National Aeronautics and Space Administration Task Load Index (NASA-TLX) provides the most widely accepted tool. However, only few studies have investigated the validity of the NASA-TLX in the health care sector. Objective: This study aimed to validate a modified version of the raw NASA-TLX in patient monitoring tasks by investigating its correspondence with expected lower and higher workload situations and its robustness against nonworkload-related covariates. This defines criterion validity. Methods: In this pooled analysis, we evaluated raw NASA-TLX scores collected after performing patient monitoring tasks in four different investigator-initiated, computer-based, prospective, multicenter studies. All of them were conducted in three hospitals with a high standard of care in central Europe. In these already published studies, we compared conventional patient monitoring with two newly developed situation awareness–oriented monitoring technologies called Visual Patient and Visual Clot. The participants were resident and staff anesthesia and intensive care physicians, and nurse anesthetists with completed specialization qualification. We analyzed the raw NASA-TLX scores by fitting mixed linear regression models and univariate models with different covariates. Results: We assessed a total of 1160 raw NASA-TLX questionnaires after performing specific patient monitoring tasks. Good test performance and higher self-rated diagnostic confidence correlated significantly with lower raw NASA-TLX scores and the subscores (all P<.001). Staff physicians rated significantly lower workload scores than residents (P=.001), whereas nurse anesthetists did not show any difference in the same comparison (P=.83). Standardized distraction resulted in higher rated total raw NASA-TLX scores (P<.001) and subscores. There was no gender difference regarding perceived workload (P=.26). The new visualization technologies Visual Patient and Visual Clot resulted in significantly lower total raw NASA-TLX scores and all subscores, including high self-rated performance, when compared with conventional monitoring (all P<.001). Conclusions: This study validated a modified raw NASA-TLX questionnaire for patient monitoring tasks. The scores obtained correctly represented the assumed influences of the examined covariates on the perceived workload. We reported high criterion validity. The NASA-TLX questionnaire appears to be a reliable tool for measuring subjective workload. Further research should focus on its applicability in a clinical setting.

23 May 2017 in Anaesthesia
Verified
Journal Article
Closed access
PDF file
PSP. Stein
P. Stein
Alexander KasererAlexander Kaserer
Alexander Kaserer
Kai SprengelKai Sprengel
Kai Sprengel
GWG. A. Wanner
G. A. Wanner
BSB. Seifert
B. Seifert
DSDonat Spahn
Donat Spahn

1 January 2020 in British Journal of Anaesthesia
Verified
Journal Article
Closed access
JRJulian Rössler
Julian Rössler
FSFelix Schoenrath
Felix Schoenrath
BSBurkhardt Seifert
Burkhardt Seifert
Alexander KasererAlexander Kaserer
Alexander Kaserer
GSGabriela H. Spahn
Gabriela H. Spahn
DSDonat Spahn
Donat Spahn

1 March 2017 in The American Journal of Emergency Medicine
Verified
Journal Article
Closed access
Alexander KasererAlexander Kaserer
Alexander Kaserer
PSPhilipp Stein
Philipp Stein
HSHans-Peter Simmen
Hans-Peter Simmen
DSDonat Spahn
Donat Spahn
VNValentin Neuhaus
Valentin Neuhaus

30 July 2020 in Sensors
Verified
Journal Article
Open access
PDF file
Sebastian D SahliSebastian D Sahli
Sebastian D Sahli
JRJulian Rössler
Julian Rössler
David Werner TschollDavid Werner Tscholl
David Werner Tscholl
JSJan-Dirk Studt
Jan-Dirk Studt
DSDonat Spahn
Donat Spahn
Alexander KasererAlexander Kaserer
Alexander Kaserer
This review provides a comprehensive and up-to-date overview of point-of-care (POC) devices most commonly used for coagulation analyses in the acute settings. Fast and reliable assessment of hemostasis is essential for the management of trauma and other bleeding patients. Routine coagulation assays are not designed to visualize the process of clot formation, and their results are obtained only after 30–90 m due to the requirements of sample preparation and the analytical process. POC devices such as viscoelastic coagulation tests, platelet function tests, blood gas analysis and other coagulometers provide new options for the assessment of hemostasis, and are important tools for an individualized, goal-directed, and factor-based substitution therapy. We give a detailed overview of the related tests, their characteristics and clinical implications. This review emphasizes the evident advantages of the speed and predictive power of POC clot measurement in the context of a goal-directed and algorithm-based therapy to improve the patient’s outcome. Interpretation of viscoelastic tests is facilitated by a new visualization technology.