I am a specialist in nutritional signaling, with a focus on glucose and lipid metabolism. With 10 years of experience conducting research in academia, I have acquired a broad understanding of the connection between nutritional disorders and metabolic diseases. My research has been dedicated to better understanding the molecular links between high-fat diet feeding and the induction of obesity and its related disorders, such as type 2 diabetes, fatty liver, and dyslipidemia. I have explored the potential of genes and proteins of interest (e.g., PCSK9, CIDEC) that control fat storage in tissues and cholesterol circulation in the blood by deciphering the mechanisms that regulate lipid droplet formation and lipoprotein homeostasis. My contributions have advanced the understanding of the physiological aspects of fasting and refeeding transitions, as well as insulin secretion and its metabolic effects. I have specifically studied nutrient signaling pathways through cell membrane recepors (e.g., LDL-Receptor, insulin mimetics) and nuclear receptors (e.g., FXR, PPARs) with applications in pathological conditions. Throughout my scientific career, I have mastered various therapeutic approaches and characterized their benefits for cardiovascular health. I have worked with small molecules (nuclear receptor pharmacology), biologics (peptide inhibitors, insulin analogs), antisense oligonucleotides, and botanical extracts (e.g., TOTUM).
Nutraveris
Ploufragan, France
Scientific Affairs
Senior Scientist or Principal Investigator
Valbiotis SA
01 Jul 2019 - 01 Dec 2023
Senior Scientist or Principal Investigator
NovoNordisk A/S
01 Apr 2016 - 01 Dec 2018
Post Doctoral Researcher
Saint Louis University
01 Feb 2012 - 01 Dec 2015
Post Doctoral Researcher
Universitat de Barcelona
01 Feb 2010 - 01 Dec 2011
Graduate Student or Post Graduate
Université de Nantes
01 Sep 2006 - 01 Oct 2009