In the context of the maritime transportation sector electrification, battery hybridization has been identified as a promising manner of meeting the critical requirements on energy and power density, as well as lifetime and safety. Today, multiple promising battery hybridization topologies have been identified, while there is not a level playing field enabling comparison between different topologies. This study bridges this gap directly by proposing a generic hybrid battery energy storage system (HBESS) design and evaluation framework in full-electric marine applications that accounts for the key design requirements in the system topology conceptualization phase. In doing so, generalized key component models, such as battery cell models, aging models, power converter models, and thermal models, are established. Additionally, given the selected key requirements in this study, the case study comparing one baseline monotype design and two HBESS topologies has shown the clear advantage of battery hybridization. Furthermore, we find that, depending on the topology selection and the specific load scenario being considered, power converter devices can also worsen the key performance indexes.