Muhamad Khairul Nazrin Khalil

Muhamad Khairul Nazrin Khalil


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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NSNorhafizah Sahril
Norhafizah Sahril
YCYee Mang Chan
Yee Mang Chan
YCYing Ying Chan
Ying Ying Chan
NANoor Ani Ahmad
Noor Ani Ahmad
MKMohd Shaiful Azlan Kassim
Mohd Shaiful Azlan Kassim
SLSiaw Hun Liew
Siaw Hun Liew
Objective: This study aims to determine the prevalence of poor self-rated health (SRH) in Malaysia and its association with sociodemographic characteristics, lifestyle behavior, chronic diseases, depression, and functional limitations in activities of daily living (ADLs) among older persons. Design: Cross-sectional. Setting, participants, and outcome measures: We used data from the National Health and Morbidity Survey 2018, a nationwide community-based study. This study was conducted using a two-stage stratified cluster sampling design. Older persons were defined as persons aged 60 years and above. SRH was assessed using the question “How do you rate your general health?” and the answers were “very good”, “good”, “moderate”, “not good”, and “very bad”. SRH was then grouped into two categories; “Good” (very good and good) and “Poor” (moderate, not good, and very bad). Descriptive and logistic regression analyses were conducted using SPSS version 25.0. Results: The prevalence of poor SRH among older persons was 32.6%. Poor SRH was significantly related to physical inactivity, depression, and limitations in activities of daily living (ADLs). Multiple logistic regression revealed that poor SRH was positively associated with those who had depression (aOR 2.92, 95% CI:2.01,4.24), limitations in ADLs (aOR 1.82, 95% CI: 1.31, 2.54), low individual income (aOR 1.66, 95% CI:1.22, 2.26), physical inactivity (aOR 1.40, 95% CI:1.08, 1.82), and hypertension (aOR 1.23, 95% CI:1.02, 1.49). Conclusions: Older persons with depression, limitations in ADLs, low income, physical inactivity, and hypertension were significantly associated with poor SRH. These findings provide information to aid health personnel and policymakers in the development and implementation of health promotion and disease prevention programs, as well as adequate evidence in planning different levels of care for the older population.

20 March 2023 in Nutrients
Verified
Journal Article
Open access
PDF file
MKMuhamad Khairul Nazrin Khalil
Muhamad Khairul Nazrin Khalil
MRMOHAMAD AZNUDDIN ABD RAZAK
MOHAMAD AZNUDDIN ABD RAZAK
FTFatin Athirah Tahir
Fatin Athirah Tahir
NSNorhafizah Sahril
Norhafizah Sahril
NSNik Adilah Shahein
Nik Adilah Shahein
MKMohd Shaiful Azlan Kassim
Mohd Shaiful Azlan Kassim
Background: Anaemia continues to be a global public health burden affecting all age groups, particularly children. Indigenous people, including the Orang Asli (OA) population in Malaysia, are at risk of anaemia due to the vast disparities in social determinants of health in their population compared to the non-indigenous population. Objectives: This review aimed to identify the prevalence and risk factors of anaemia among OA children in Malaysia and analyse the knowledge gaps. Methods: A systematic search was conducted in PubMed, Cochrane Library, Scopus and Google Scholar databases. This review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews (PRISMA-ScR) guidelines. Results: This review identified six studies involving the participation of OA children from eight subtribes residing in Peninsular Malaysia. The overall prevalence of anaemia among OA children ranged from 21.6 to 80.0%, with iron deficiency anaemia prevalence at 34.0%. The risk factors of anaemia among OA children reported from one study in this review were being younger than ten years old children (AOR 2.11 (95% CI 1.23, 3.63)) and moderate to heavy Ascaris infections (AOR 2.05 (95% CI 1.12, 3.76)). There was no data from OA children from certain age groups and subtribes. Additionally, there is a paucity of data on risk factors for anaemia among OA children from the currently available evidence. Conclusion: The prevalence of anaemia among OA children poses a moderate to severe public health concern. Therefore, more comprehensive studies in the future are needed to address the gaps identified in this review, primarily regarding anaemia risk factors. This data would encourage policymakers in devising effective national prevention strategies to improve morbidity and mortality among OA children in the future.

5 August 2022 in JMIR Research Protocols
Verified
Journal Article
Open access
SAShazana Rifham Abdullah
Shazana Rifham Abdullah
NANur Hayati Azizul
Nur Hayati Azizul
RZRuziana Mona Wan Mohd Zin
Ruziana Mona Wan Mohd Zin
NSNur Suffia Sulaiman
Nur Suffia Sulaiman
NKNorhayati Mustafa Khalid
Norhayati Mustafa Khalid
MNMohd Fairulnizal Md Noh
Mohd Fairulnizal Md Noh
Background: Overweight and obesity among adults are a growing global public health threat and an essential risk factor for various noncommunicable diseases. Although intermittent fasting is a generally new dietary approach to weight management that has been increasingly practiced worldwide, the effectiveness of 2 days per week dry fasting remains unclear. Objective: The Cardiometabolic and Anthropometric Outcomes of Intermittent Fasting study aims to determine the cardiometabolic, anthropometric, dietary intake, and quality of life changes among civil servants with overweight and obesity, following combined intermittent fasting and healthy plate (IFHP) and healthy plate (HP) and explore the participants’ experiences. Methods: We designed a mixed methods quasi-experimental study to evaluate the effectiveness of the IFHP and HP methods among adults with overweight and obesity. A total of 177 participants were recruited for this study, of which 91 (51.4%) were allocated to the IFHP group and 86 (48.6%) to the HP group. The intervention comprised 2 phases: supervised (12 weeks) and unsupervised (12 weeks). Data collection was conducted at baseline, after the supervised phase (week 12), and after the unsupervised phase (week 24). Serum and whole blood samples were collected from each participant for analysis. Data on sociodemographic factors, quality of life, physical activity, and dietary intake were also obtained using questionnaires during data collection. Results: Most of the participants were female (147/177, 83.1%) and Malay (141/177, 79.7%). The expected outcomes of this study are changes in body weight, body composition, quality of life, physical activity, dietary intake, and cardiometabolic parameters such as fasting blood glucose, 2-hour postprandial blood glucose, hemoglobin A1c, fasting insulin, and lipid profile. Conclusions: The Cardiometabolic and Anthropometric Outcomes of Intermittent Fasting study is a mixed methods study to evaluate the effectiveness of combined IFHP and HP interventions on cardiometabolic and anthropometric parameters and explore participants’ experiences throughout the study. Trial Registration: ClinicalTrials.gov NCT05034653; https://clinicaltrials.gov/ct2/show/NCT05034653 International Registered Report Identifier (IRRID): RR1-10.2196/33801

10 April 2024 in JMIR Formative Research
Verified
Journal Article
Open access
SAShazana Rifham Abdullah
Shazana Rifham Abdullah
RZRuziana Mona Wan Mohd Zin
Ruziana Mona Wan Mohd Zin
NANur Hayati Azizul
Nur Hayati Azizul
NSNur Suffia Sulaiman
Nur Suffia Sulaiman
NKNorhayati Mustafa Khalid
Norhayati Mustafa Khalid
MNMohd Fairulnizal Md Noh
Mohd Fairulnizal Md Noh
Background: Adult obesity and overweight pose a substantial risk to global public health and are associated with various noncommunicable diseases. Although intermittent fasting (IF) is increasingly used as a relatively new dietary strategy for weight loss, the effectiveness of 2 days per week of dry fasting remains unknown. Objective: This study aims to evaluate the effectiveness of a combined dry IF and healthy plate (IFHP) and healthy plate (HP) intervention in improving anthropometric outcomes and body composition. Methods: This nonrandomized controlled trial involved 177 adults who were overweight and obese. Among them, 91 (51.4%) were allocated to the IFHP group and 86 (48.6%) were allocated to the HP group. The overall study duration was 6 months (October 2020 to March 2021). The intervention was divided into 2 phases: supervised (3 months) and unsupervised (3 months). The data were collected at baseline, after the supervised phase (month 3), and after the unsupervised phase (month 6). Anthropometric (weight, height, waist circumference, and hip circumference) and body composition (body fat percentage, body fat mass, skeletal muscle mass, and visceral fat area) data were measured at all 3 data collection points. Sociodemographic data were obtained using a questionnaire at baseline. Results: Most participants were female (147/177, 83.1%) and Malay (141/177, 79.7%). After 3 months, there were significant reductions in weight (difference −1.68; P<.001), BMI (difference −0.62; P<.001), body fat percentage (difference −0.921; P<.001), body fat mass (difference −1.28; P<.001), and visceral fat area (difference −4.227; P=.008) in the IFHP group, whereas no significant changes were observed in the HP group. Compared to baseline, participants in the IFHP group showed a significant decrease in weight (difference −1.428; P=.003), BMI (difference −0.522; P=.005), body fat percentage (difference −1.591; P<.001), body fat mass (difference −1.501; P<.001), visceral fat area (difference −7.130; P<.001), waist circumference (difference −2.304; P=.001), and hip circumference (difference −1.908; P=.002) at month 6. During the unsupervised phase, waist (IFHP difference −3.206; P<.001, HP difference −2.675; P=.004) and hip (IFHP difference −2.443; P<.001; HP difference −2.896; P<.001) circumferences were significantly reduced in both groups (P<.01), whereas skeletal muscle mass (difference 0.208; P=.04) and visceral fat area (difference −2.903; P=.003) were significantly improved in the IFHP group only. No significant difference in the between-group comparison was detected throughout the intervention (all P>.05). Conclusions: A combined IFHP intervention was effective in improving anthropometric outcomes and body composition in adults with overweight and obesity. International Registered Report Identifier (IRRID): RR2-10.2196/33801.

30 October 2025 in Asia Pacific Journal of Public Health
Verified
Journal Article
Closed access
NMNurulasmak Mohamed
Nurulasmak Mohamed
HYHabibah Yacob @ Ya’AKub
Habibah Yacob @ Ya’AKub
SSSuzana Sharif
Suzana Sharif
YCYing Ying Chan
Ying Ying Chan
MKMuhamad Khairul Nazrin Khalil
Muhamad Khairul Nazrin Khalil
Betel quid chewing is a traditional practice prevalent in many Asian countries, including among the Indigenous people (Orang Asli) in Malaysia. This habit poses serious health risks, such as oral cancer, diabetes, hypertension, cardiovascular disease, and adverse pregnancy outcomes. Despite these known health implications, there is limited data and targeted interventions addressing this culturally significant behavior among the marginalized Orang Asli population. This study examined the prevalence and sociodemographic and risk behavioral factors associated with betel quid chewing among Orang Asli communities in Peninsular Malaysia. Data of 10,787 respondents aged 13 years and above were extracted from the 2022 Orang Asli Health Survey (OAHS), a population-based cross-sectional study using stratified random sampling. Complex sample design analysis and multivariable logistic regression were applied. The prevalence of betel quid chewing was 45.5%. Significant factors associated with betel quid chewing included being female (adjusted odds ratio [aOR] = 1.58,95% CI [1.21, 2.06]), Proto-Malay tribe (aOR = 7.41,95% CI [3.87, 14.15]), married/living with a partner (aOR = 1.60,95% CI: [0.28, 2.01]), employed (aOR = 2.80,95% CI [1.35, 5.76]), housewife/homemaker (aOR = 2.87,95% CI [1.35, 6.11]), tobacco user (aOR = 2.22,95% CI [1.85, 2.66]), and alcohol drinker (aOR = 1.41,95% CI [1.08, 1.85]). These findings highlight the need for culturally tailored interventions and preventive strategies targeting high-risk subgroups, such as married women and the Proto-Malay tribe, to reduce betel quid use and its associated health consequences.

24 September 2021 in JMIR Preprints
Verified
Preprint
Open access
SAShazana Rifham Abdullah
Shazana Rifham Abdullah
NANur Hayati Azizul
Nur Hayati Azizul
RZRuziana Mona Wan Mohd Zin
Ruziana Mona Wan Mohd Zin
NSNur Suffia Sulaiman
Nur Suffia Sulaiman
NKNorhayati Mustafa Khalid
Norhayati Mustafa Khalid
MNMohd Fairulnizal Md Noh
Mohd Fairulnizal Md Noh
BACKGROUND Overweight and obesity among adults is a growing global public health threat and an essential risk factor for various non-communicable diseases. Although intermittent fasting is a generally new dietary approach to weight management that has been increasingly practised worldwide, the effectiveness of two-days per week dry fasting is still unclear. OBJECTIVE This study aimed to determine the cardiometabolic, anthropometric, dietary intake and quality of life changes among overweight and obese civil servants following combined Intermittent Fasting and Healthy Plate (IFHP) and Healthy Plate (HP), and to explore the participants’ experience. METHODS We designed a mixed-method quasi-experimental study that evaluates the effectiveness of IFHP and HP methods among overweight and obese adults. A total of 177 participants were recruited in this study, of which 91 were allocated in the IFHP group and 86 in the HP group. The intervention comprised two phases; supervised (12 weeks) and unsupervised (12 weeks). The data collection was conducted during baseline, after the supervised phase (at week 12), and after the unsupervised phase (at week 24). For each participant, serum and whole blood were collected for analysis. Data on socio-demographic, quality of life, physical activity and dietary intake were also obtained using questionnaires during data collection. RESULTS The majority of the participants were females (n=147, 83.7%) and Malays (n=141, 79.6%). The expected outcomes of this study are changes in body weight, body compositions, quality of life, physical activity, dietary intake and cardiometabolic parameters such as fasting blood glucose, 2-hour post prandial blood glucose, HbA1C, fasting insulin and lipid profile. CONCLUSIONS The CAIFA study is a mixed-method study to evaluate the effectiveness of intermittent fasting on cardiometabolic and anthropometric parameters and to explore participants’ experience throughout the study. CLINICALTRIAL ClinicalTrials.gov NCT05034653