Simone Katrin Dold

Simone Katrin Dold


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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2 February 2023 in Children
Verified
Journal Article
Open access
PDF file
SDSimone Katrin Dold
Simone Katrin Dold
DHDr. Nikolaus HAAS
Dr. Nikolaus HAAS
Christian ApitzChristian Apitz
Christian Apitz
Children and adolescents with congenital heart disease (CHD) should be encouraged to adopt a physically active lifestyle, ideally by participating in sports activities at school and sports clubs. Children with complex CHD or other risk factors (for example, pacemakers, cardioverter-defibrillators, channelopathies) may, however, need specific individualized training programs. This review article summarizes the current knowledge regarding the clinical effects of sports and exercise training on CHD and its pathophysiologic mechanisms. An evidence-based approach based on a literature search, using PubMed, Medline, CINHAL, Embase, and the Cochrane Library was conducted, last completed on 30 December 2021. In studies with 3256 CHD patients in total, including 10 randomized controlled trials, 14 prospective interventional trials, 9 observational trials, and 2 surveys, exercise training has been shown to improve exercise capacity and physical activity, motoric skills, muscular function, and quality of life. Sports and exercise training appears to be effective and safe in CHD patients. Despite being cost-efficient, training programs are currently scarcely reimbursed; therefore, support from healthcare institutions, commissioners of healthcare, and research-funding institutions is desirable. There is a strong need to establish specialized rehabilitation programs for complex CHD patients to enhance these patients’ access to this treatment intervention. Further studies may be desirable to confirm these data to investigate the impact on risk profiles and to identify the most advantageous training methodology and underlying pathophysiological mechanisms.

12 February 2024 in Children
Verified
Journal Article
Open access
PDF file
MMMaurice Pablo Mall
Maurice Pablo Mall
JWJohanna Wander
Johanna Wander
ALAnne Lentz
Anne Lentz
AJAndré Jakob
André Jakob
FOFelix Sebastian Oberhoffer
Felix Sebastian Oberhoffer
SDSimone Katrin Dold
Simone Katrin Dold
(1) Background: Cardiorespiratory fitness (CRF) is known to be a prognostic factor regarding long-term morbidity and mortality. This study aimed to develop a standardized Stair Climbing Test (SCT) with a reliable correlation to spiroergometry and the 6MWT which can be used in healthy children as well as patients with congenital heart disease (CHD) and a restricted exercise capacity. (2) Methods: A total of 28 healthy participants aged 10–18 years were included. We tested the individuals’ CRF by cardiopulmonary exercise testing (CPET) on a treadmill, the 6MWT, and a newly developed Stair Climbing Test (SCT). For the SCT, we defined a standardized SCT protocol with a total height of 13.14 m to achieve maximal exercise effects while recording time and vital parameters. To compare the SCT, the 6 Min Walking Test, and CPET, we introduced an SCT-Index that included patient data (weight, height) and time. To assess the SCT’s feasibility for clinical practice, we also tested our protocol with five adolescents with complex congenital heart disease (i.e., Fontan circulation). (3) Results: A strong correlation was observed between SCT-Index and O2 pulse (r = 0.921; p < 0.001). In addition, when comparing the time achieved during SCT (tSCT) with VO2max (mL/min/kg) and VO2max (mL/min), strong correlations were found (r = −0.672; p < 0.001 and r = −0.764; p < 0.001). Finally, we determined a very strong correlation between SCT-Index and VO2max (mL/min) (r = 0.927; p = <0.001). When comparing the 6MWD to tSCT, there was a moderate correlation (r = −0.544; p = 0.003). It appears to be feasible in patients with Fontan circulation. (4) Conclusions: We were able to demonstrate that there is a significant correlation between our standardized SCT and treadmill CPET. Therefore, we can say that the SCT can be used as an easy supplement to CPET and in certain contexts, it can also be used as a screening tool when CPET is not available. The advantages would be that the SCT is a simple, quick, cost-effective, and reliable standardized (sub)maximal exercise test to evaluate CRF in healthy children on a routine basis. We can even assume that it can be used in patients with congenital heart disease.

29 April 2025 in Children
Verified
Journal Article
Open access
PDF file
JWJennifer Wieprecht
Jennifer Wieprecht
DGDelphina Gomes
Delphina Gomes
FVFederico Morassutti Vitale
Federico Morassutti Vitale
SDSimone Katrin Dold
Simone Katrin Dold
SSSamar Shamas
Samar Shamas
MSMeike Schrader
Meike Schrader
Background/Objectives: Today, digital technologies are integral to children’s lives; their increasing use, however, may raise health concerns. This study aims to examine the effect of screen time on physical activity and lifestyle factors in German school children. Methods: As part of the prospective hand-on-heart-study (“Hand-aufs-Herz”), a comprehensive cardiovascular system check-up examination was conducted on 922 German schoolchildren. The pupils were asked for a self-report on their daily physical activities and club sports. The examinations on-site contained measurements of the pupils’ weight and height as well as their physical fitness, which was assessed by a stair-climbing test. Results: A large proportion of pupils had a screen time of more than 2 h daily, regardless of the day of the week (63–76%). In fact, pupils with a screen time ≥ 2 h were more likely to achieve poor grades in school (weekday ORs 3.23, 95% CI 1.76, 5.95; weekend ORs 3.28, 95% CI 1.53, 7.00) and not be members of a sports club (weekday ORs 2.35, 95% CI 1.68, 3.29; weekend ORs 2.13, 95% CI 1.44, 3.14). Pupils who did not meet both recommendations for physical activity and screen time walked <5000 steps daily (60%), had a high proportion of overweight/obesity (40%), were non-swimmers (38.5%), spent ≥7 h sitting (35.8%), and slept fewer hours than recommended (30%). It has also been shown that longer screen time has a negative impact on the lifestyle of children and young people. Conclusions: Our results show that excessive screen time in children is linked to higher weight and an unhealthy lifestyle, increasing long-term cardiovascular risks. Public health initiatives aimed at reducing screen time, promoting physical activity, and encouraging healthier habits are essential to improve children’s overall health and prevent future chronic diseases.

26 March 2025 in Children
Verified
Journal Article
Open access
PDF file
MSMeike Schrader
Meike Schrader
JWJennifer Wieprecht
Jennifer Wieprecht
FVFederico Morassutti Vitale
Federico Morassutti Vitale
SDSimone Katrin Dold
Simone Katrin Dold
SSSamar Shamas
Samar Shamas
DGDelphina Gomes
Delphina Gomes
Background/Objectives: physical activity (PA) in children offers lifelong benefits, yet nearly four in five children are insufficiently active. We examined sex-specific differences in sport participation by sport type and its association with weight status. Methods: in the ongoing hand-on-heart-study (“Hand-aufs-Herz”), comprehensive data on sociodemographic profiles, PA, and anthropometry were collected from 922 school-aged children, adolescents, and young adults (8–20 years) in Germany. Sex-specific differences in sport participation, sport types, and weight status were analyzed using descriptive statistics and logistic regression models. Results: based on the eligibility criteria for analysis (ages 8–18 years), 883 pupils were included (mean age 13.1 ± 2.4 years), 406 (46%) were females. Compared to females, males had a 43% higher chance of being members of a sports club and were more likely to spend more days/week on sports (44–85%). Males participated more in football, martial arts, and basketball while females favored gymnastics and volleyball. As age increased, males had a 30% higher likelihood of not being sports club members (females: 13%). Overweight/obese males had twice the risk of lacking sports memberships. The largest body mass index (BMI) difference was found in males and females participating in athletics, with −4.64 kg/m2 (males) and −1.99 kg/m2 (females) compared to their counterparts without club memberships. Conclusions: in conclusion, sports participation should be encouraged especially among females and overweight/obese males. Targeted strategies should focus on promoting inclusive and non-competitive activities that cater to their interests.

28 July 2025 in Children
Verified
Journal Article
Open access
PDF file
FVFederico Morassutti Vitale
Federico Morassutti Vitale
JWJennifer Wieprecht
Jennifer Wieprecht
MBMaren Baethmann
Maren Baethmann
DGDelphina Gomes
Delphina Gomes
ATAnja Tengler
Anja Tengler
MSMeike Schrader
Meike Schrader
Background/Objectives: Cardiorespiratory fitness (CRF) is of great interest in children and adolescents. Due to the limited availability of cardiopulmonary exercise testing, simple and reliable alternatives are needed. A stair climbing test (SCT) for the assessment of CRF developed at the Department of Pediatric Cardiology of the LMU University Hospital in Munich showed a strong correlation with VO2max. The aim of this study is to prove its feasibility in a non-clinical setting and to analyse its results in a larger study population. Methods: During the “Hand aufs Herz” study, a comprehensive cardiovascular examination was carried out on 922 pupils and siblings (13.2 ± 7.8 years) at a high school in Bavaria. The SCT was performed to evaluate CRF: participants had to run up and down a total of four floors (14.8 m) as quickly as possible without skipping steps or holding on to the banister. Absolute time has been normalized over the standard height of 12 m to allow comparisons with different settings. An SCT Index was calculated to adjust results to the different weights of participants and the exact height of the staircase. Results: The SCT proved to be easily feasible and safe in non-clinical contexts. Out of 922 participants, 13 (1.4%) were not able to perform the test, and 3 (0.3%) had to interrupt it following fatigue or stumbling. A total of 827 participants aged from 9 to 17 years (13.1 ± 2.1 years, 45.8% girls) had a mean absolute SCT time of 53.4 ± 6.2 s and 43.3 ± 5.1 s when normalized over 12 m. Conclusions: The SCT represents a simple, cost- and time-saving test that allows a rapid and solid assessment of cardiorespiratory fitness in children and adolescents. We could demonstrate that it is safe and feasible in non-clinical contexts. Its short duration and universal applicability are valuable advantages that could facilitate the establishment of a repetitive cardiovascular screening in the pediatric population, particularly in outpatient departments or settings with low-resource systems.

29 February 2024 in Preprints.org
Verified
Preprint
Open access
PDF file
JWJohanna Wander
Johanna Wander
MMMaurice Pablo Mall
Maurice Pablo Mall
ALAnne Lentz
Anne Lentz
MSMeike Schrader
Meike Schrader
DHDr. Nikolaus HAAS
Dr. Nikolaus HAAS
SDSimone Katrin Dold
Simone Katrin Dold
(1) Background: Cardiorespiratory fitness (CRF) is a prognostic factor regarding long time morbidity and mortality. To assess CRF the well-known gold standard is cardiopulmonary exercise testing (CPET), which is a time consuming and expensive test. Therefore, alternative methods for routine evaluation of CRF are needed for the general population as well as for specific patient groups such as children and young adults with congenital heart disease. The Stair Climbing Test (SCT) is a simple and resource saving test reported in the current literature. This test is used in various settings to assess different health associated risk factors including cardiorespiratory fitness, muscular resilience, therapy effectiveness or pre- and postoperative morbidity and mortality.