Carlos Jimenez

Dr. Carlos Jimenez

Departamento de Química, Facultade de Ciencias e Centro de Investigacións Científicas Avanzadas (CICA), Universidade da Coruña, 15071 A Coruña, Spain
orcid

Research Focus & Metrics

Academic Career Length

41Years (1986-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 September 2018 in ACS Medicinal Chemistry Letters
Verified
Journal Article
Closed access
Carlos JimenezCarlos Jimenez
Carlos Jimenez

1 January 1994 in Natural Product Reports
Verified
Journal Article
Closed access
PDF file
Carlos JimenezCarlos Jimenez
Carlos Jimenez
RRRicardo Riguera
Ricardo Riguera

19 May 2023 in Marine Drugs
Verified
Journal Article
Open access
PDF file
Susana P. GaudencioSusana P. Gaudencio
Susana P. Gaudencio
EBEngin Bayram
Engin Bayram
Lada Lukić BilelaLada Lukić Bilela
Lada Lukić Bilela
MCMercedes Cueto
Mercedes Cueto
Ana R. Diaz-MarreroAna R. Diaz-Marrero
Ana R. Diaz-Marrero
Deniz TasdemirDeniz Tasdemir
Deniz Tasdemir
Natural Products (NP) are essential for the discovery of novel drugs and products for numerous biotechnological applications. The NP discovery process is expensive and time-consuming, having as major hurdles dereplication (early identification of known compounds) and structure elucidation, particularly the determination of the absolute configuration of metabolites with stereogenic centers. This review comprehensively focuses on recent technological and instrumental advances, highlighting the development of methods that alleviate these obstacles, paving the way for accelerating NP discovery towards biotechnological applications. Herein, we emphasize the most innovative high-throughput tools and methods for advancing bioactivity screening, NP chemical analysis, dereplication, metabolite profiling, metabolomics, genome sequencing and/or genomics approaches, databases, bioinformatics, chemoinformatics, and three-dimensional NP structure elucidation.

11 October 2010 in Natural Product Reports
Verified
Journal Article
Closed access
PDF file
RNRamon Novoa-Carballal
Ramon Novoa-Carballal
EFEduardo Fernandez-Megia
Eduardo Fernandez-Megia
Carlos JimenezCarlos Jimenez
Carlos Jimenez
RRRicardo Riguera
Ricardo Riguera
Covering: up to May 2010 The main methods for the simplification of the NMR of complex mixtures by selective attenuation/suppression of the signals of certain components are presented. The application of relaxation, diffusion and PSR filters and other techniques (J-resolution, TOCSY, etc.), to biological samples, pharmaceuticals, foods, living organisms and natural products are illustrated with examples.

1 May 1991 in The Journal of Organic Chemistry
Verified
Journal Article
Closed access
Carlos JimenezCarlos Jimenez
Carlos Jimenez
EQEmilio Quinoa
Emilio Quinoa
MAMadeline Adamczeski
Madeline Adamczeski
LHLisa M. Hunter
Lisa M. Hunter
PCPhillip Crews
Phillip Crews

24 January 2012 in ACS Chemical Biology
Verified
Journal Article
Closed access
ARAna Belén Rodríguez-Urra
Ana Belén Rodríguez-Urra
Carlos JimenezCarlos Jimenez
Carlos Jimenez
MNMaría Isabel Nieto
María Isabel Nieto
Jaime RodríguezJaime Rodríguez
Jaime Rodríguez
HHHideo Hayashi
Hideo Hayashi
UUUnai Ugalde
Unai Ugalde