Leonardo Zambotti-Villela

Dr. Leonardo Zambotti-Villela


Research Focus & Metrics

Academic Career Length

22Years (2005-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 November 2015 in Revista Brasileira de Farmacognosia
Verified
Journal Article
Open access
LMLevi Pompermayer Machado
Levi Pompermayer Machado
LCLuciana R. Carvalho
Luciana R. Carvalho
MYMaria Cláudia M. Young
Maria Cláudia M. Young
ECElaine M. Cardoso-Lopes
Elaine M. Cardoso-Lopes
DCDanilo C. Centeno
Danilo C. Centeno
NYNair S. Yokoya
Nair S. Yokoya
Alzheimer's disease affects nearly 36.5 million people worldwide, and acetylcholinesterase inhibition is currently considered the main therapeutic strategy against it. Seaweed biodiversity in Brazil represents one of the most important sources of biologically active compounds for applications in phytotherapy. Accordingly, this study aimed to carry out a quantitative and qualitative assessment of Hypnea musciformis (Wulfen) J.V. Lamouroux, Ochtodes secundiramea (Montagne) M.A. Howe, and Pterocladiella capillacea (S.G. Gmelin) Santelices & Hommersand (Rhodophyta) in order to determine the AChE effects from their extracts. As a matter of fact, the O. secundiramea extract showed 48% acetylcholinesterase inhibition at 400μg/ml. The chemical composition of the bioactive fraction was determined by gas chromatography–mass spectrometry (GC–MS); this fraction is solely composed of halogenated monoterpenes, therefore allowing assignment of acetylcholinesterase inhibition activity to them

1 November 2018 in Industrial Crops and Products
Verified
Journal Article
Closed access
PSPerla M. Santos
Perla M. Santos
DBDanilo L.J. Batista
Danilo L.J. Batista
LRLuiz A.F. Ribeiro
Luiz A.F. Ribeiro
EBElisangela F. Boffo
Elisangela F. Boffo
MCMartins D. de Cerqueira
Martins D. de Cerqueira
Paulo Roberto RibeiroPaulo Roberto Ribeiro
Paulo Roberto Ribeiro

8 July 2016 in Journal of Applied Phycology
Verified
Journal Article
Closed access
PDF file
CPClaudio Martin Pereira Pereira
Claudio Martin Pereira Pereira
CNCamila F. P. Nunes
Camila F. P. Nunes
Leonardo Zambotti-VillelaLeonardo Zambotti-Villela
Leonardo Zambotti-Villela
NSNivia M. Streit
Nivia M. Streit
DDDaiane Dias
Daiane Dias
PNPio Colepicolo Neto
Pio Colepicolo Neto

11 September 2018 in Journal of Applied Phycology
Verified
Journal Article
Closed access
PDF file
MFMiriam Falkenberg
Miriam Falkenberg
ENEliana Nakano
Eliana Nakano
Leonardo Zambotti-VillelaLeonardo Zambotti-Villela
Leonardo Zambotti-Villela
GZGabriele A. Zatelli
Gabriele A. Zatelli
APAna Claudia Philippus
Ana Claudia Philippus
MGMarcia Graminha
Marcia Graminha

26 April 2013 in Journal of Applied Phycology
Verified
Journal Article
Closed access
PDF file
LMLuiz Fernando Mendes
Luiz Fernando Mendes
Leonardo Zambotti-VillelaLeonardo Zambotti-Villela
Leonardo Zambotti-Villela
PCPio Colepicolo
Pio Colepicolo
EMEliane Marinho-Soriano
Eliane Marinho-Soriano
Cassius Vinicius StevaniCassius Vinicius Stevani
Cassius Vinicius Stevani
NYNair Sumie Yokoya
Nair Sumie Yokoya

22 March 2023 in Phycology
Verified
Journal Article
Open access
PDF file
MHMariana de Sousa Santos Hempel
Mariana de Sousa Santos Hempel
PNPio Colepicolo Neto
Pio Colepicolo Neto
Leonardo Zambotti-VillelaLeonardo Zambotti-Villela
Leonardo Zambotti-Villela
With the growth in the number of people searching for ways to improve personal care, the consumer finds the solution in cosmetic products. However, this demand is currently made concomitantly with the demand for products of natural origin, including seaweed. Algae, in their composition, are full of bioactive compounds with several applications. Therefore, their insertion in cosmetics is evidenced in the high number of scientific studies, which makes this natural resource potentially useful for the cosmetic industry. From this, a review was conducted with the aim of highlighting some of these active compounds and the latent applicability and versatility of others. In addition, the best way to add to the production of these substances while staying in alignment with green consumption, the design of biorefineries, and the promising production of macroalgae on a large scale using green technologies was sought.