Shugeng Cao

Dr. Shugeng Cao

Department of Pharmaceutical Sciences, University of Hawaii at Hilo, Hilo, HI 96720-4091 Hawaii, United States
orcid

Research Focus & Metrics

Academic Career Length

30Years (1997-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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30 September 2016 in Bioconjugate Chemistry
Verified
Journal Article
Closed access
GPGiulio F. Paciotti
Giulio F. Paciotti
JZJielu Zhao
Jielu Zhao
Shugeng CaoShugeng Cao
Shugeng Cao
PBPeggy J. Brodie
Peggy J. Brodie
LTLawrence Tamarkin
Lawrence Tamarkin
DKDavid G. I. Kingston
David G. I. Kingston

3 July 2020 in Phytochemistry Reviews
Verified
Journal Article
Closed access
PDF file
CWCong Wang
Cong Wang
STSiyan Tang
Siyan Tang
Shugeng CaoShugeng Cao
Shugeng Cao

25 April 2022 in Proceedings of the National Academy of Sciences
Verified
Journal Article
Open access
MFMarnie L. Freckelton
Marnie L. Freckelton
BNBrian T. Nedved
Brian T. Nedved
YCYou-Sheng Cai
You-Sheng Cai
Shugeng CaoShugeng Cao
Shugeng Cao
HTHelen Turano
Helen Turano
MHMichael G. Hadfield
Michael G. Hadfield
Significance: New surfaces in the sea are quickly populated by dense communities of invertebrate animals, whose establishment and maintenance require site-specific settlement of larvae from the plankton. Larvae selectively settle in sites where they can metamorphose and thrive largely due to inductive cues from bacteria residing on these surfaces. However, the nature of the cues used to identify “right places” has remained enigmatic. Here, we demonstrate that lipopolysaccharide, the main component of the outer membrane of Gram-negative bacteria from the bacterium Cellulophaga lytica , induces metamorphosis for a marine worm. We then discuss the likelihood that lipopolysaccharide provides the variation necessary to explain settlement site selectivity for many of the bottom-living invertebrate animals that metamorphose in response to bacterial biofilms.

7 May 2021 in Molecules
Verified
Journal Article
Open access
PDF file
WCWang Cong
Wang Cong
WDWeisheng Du
Weisheng Du
HLHuanyun Lu
Huanyun Lu
JLJianzhou Lan
Jianzhou Lan
KLKailin Liang
Kailin Liang
Shugeng CaoShugeng Cao
Shugeng Cao
Marine actinomycetes, Streptomyces species, produce a variety of halogenated compounds with diverse structures and a range of biological activities owing to their unique metabolic pathways. These halogenated compounds could be classified as polyketides, alkaloids (nitrogen-containing compounds) and terpenoids. Halogenated compounds from marine actinomycetes possess important biological properties such as antibacterial and anticancer activities. This review reports the sources, chemical structures and biological activities of 127 new halogenated compounds originated mainly from Streptomyces reported from 1992 to 2020.

2 May 2016 in Organic Letters
Verified
Journal Article
Closed access
CLChun-Shun Li
Chun-Shun Li
GRGang Ren
Gang Ren
BYBao-Jun Yang
Bao-Jun Yang
GMGabriella Miklossy
Gabriella Miklossy
JTJames Turkson
James Turkson
Shugeng CaoShugeng Cao
Shugeng Cao

31 August 2018 in Journal of Natural Products
Verified
Journal Article
Closed access
YCYou-Sheng Cai
You-Sheng Cai
ASAriel M. Sarotti
Ariel M. Sarotti
TZTing-Lan Zhou
Ting-Lan Zhou
RHRong Huang
Rong Huang
GQGuofu Qiu
Guofu Qiu
SYSheng-Ping Yang
Sheng-Ping Yang