Nemes Iulia

Dr. Nemes Iulia

Ophthalmology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Cluj, Romania
orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
8 November 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
MHMadalina Claudia Hapca
Madalina Claudia Hapca
GMGeorge Adrian Muntean
George Adrian Muntean
NINemes Iulia
Nemes Iulia
Stefan Cristian VesaStefan Cristian Vesa
Stefan Cristian Vesa
Simona-Delia NicoaraSimona-Delia Nicoara
Simona-Delia Nicoara
Aim: The aim of this study was to evaluate the visual outcome of lens dislocation and subluxation managed by pars plana vitrectomy (PPV) and lensectomy in patients with open (OGIs) or closed globe injuries (CGIs). Methods: Medical records of 70 consecutive patients treated by PPV and lensectomy over a period of 11 years (1 January 2010–31 December 2020) were retrospectively reviewed. We collected demographic data, best corrected visual acuity (BCVA) using a Snellen Chart pre- and postoperatively, associated ocular injuries and treatment strategy. Visual outcome was evaluated according to the final BCVA which was defined as poor <0.1 or good ≥0.1. Results: The mean age was 57.9 ± 17.6 years. CGIs were present in 49 (70.0%) cases and open OGIs in 21 (30.0%) cases. The dislocation mechanism was zonular lysis in 59 cases (84.3%) and capsular rupture in 11 cases (15.7%). The intraocular lens implant (IOL) was sutured to the sclera in 51 (72.9%) cases or positioned in the capsular bag or in the sulcus in 3 (4.3%) cases and 1 (1.4%) case, respectively, whereas 15 (21.4%) patients remained aphakic. A good BCVA ≥ 0.1 was achieved in 45.71% of the eyes. The presence of retinal detachment (RD) (p = 0.014), iridodonesis (p = 0.011) and initial BCVA (p = 0.000) achieved statistical significance in predicting visual outcome. After treatment, 45.71% of patients achieved a final BCVA ≥ 0.1. Conclusion: RD, iridodonesis and initial BCVA were risk factors for poor visual outcome in our series.

1 August 2022 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
MHMadalina Claudia Hapca
Madalina Claudia Hapca
GMGeorge Adrian Muntean
George Adrian Muntean
NINemes Iulia
Nemes Iulia
Stefan Cristian VesaStefan Cristian Vesa
Stefan Cristian Vesa
Simona-Delia NicoaraSimona-Delia Nicoara
Simona-Delia Nicoara
Aim: To evaluate the visual outcome of penetrating ocular injuries with a retained intraocular foreign body (IOFB) managed by pars plana vitrectomy (PPV) and to describe the risk factors associated with poor visual acuity and retinal detachment (RD) development. Methods: Medical records of 56 patients with IOFB that were removed by PPV over a period of 11 years (1 January 2010–31 December 2020) were reviewed. We extracted the demographic data, initial and final best corrected visual acuity (BCVA) using standard Snellen chart, IOFB characteristics, complications and surgical details. Outcome was evaluated according to the final BCVA: poor <0.1, good 0.1–3mm in 30 (53.6%) cases. Preoperative RD was identified in 12 (21.4%) cases and endophthalmitis in 17 cases (30.4%). IOFBs larger than 3 mm and retinal location were associated with RD development. Poor visual outcome was associated with initial BCVA, retinal location, RD and endophthalmitis. Conclusion: Initial BCVA, retinal foreign body, RD and endophthalmitis were risk factors for poor visual outcome.

10 April 2023 in Diagnostics
Verified
Journal Article
Open access
PDF file
NINemes Iulia
Nemes Iulia
ADAna-Maria Drăgan
Ana-Maria Drăgan
MHMadalina Claudia Hapca
Madalina Claudia Hapca
MOMara Oaida
Mara Oaida
The purpose of this study is to analyze and compare pediatric normative data for the retinal nerve fiber layer of Romanian children using two different spectral domain optical coherence tomographs. Due to different scanning speeds and axial and transverse resolution, the results of the measurements of scans cannot be transposed. A total of 140 healthy children aged 4 to 18 were enrolled in the study. Overall, 140 eyes were scanned with a Spectralis SD-OCT (Heidelberg Technology), and the other 140 eyes were imaged with a Copernicus REVO SOCT (Optopol Technology (Zawiercie, Poland)). The mean global RNFL thickness and average RNFL thickness for the four quadrants were measured and compared. The average peripapillary RNFL thickness measured with the Spectralis was 104.03 ± 11.42 (range 81 to 126 µm), while the one measured with the Revo 80 was 127.05 ± 15.6 (range 111.43–158.28). The RNFL thickness measurements taken with the Spectralis in the superior, inferior, nasal, and temporal quadrants were 132 ±19.1, 133.5 ± 21.77, 74 ± 16.48, and 73 ± 11.95 µm, respectively, while those taken with the Revo 80 were 144.44 ± 9.25, 144.86 ±23.12, 96.49 ± 19.41, and 77 ± 11.4 µm, respectively. Multivariate analysis showed that the average RNFL thickness was not influenced by gender or eye laterality and was negatively correlated with age when we used the Spectralis device. This study provides normative data for SD-OCT peripapillary RNFL in healthy Romanian children for two different tomographs. These data help the clinician evaluate and interpret the results of optical coherence tomography for a child, taking into consideration all the technical and individual parameters.

26 August 2024 in Diagnostics
Verified
Journal Article
Open access
PDF file
NINemes Iulia
Nemes Iulia
AȚAlexandru Țîpcu
Alexandru Țîpcu
MHMadalina Claudia Hapca
Madalina Claudia Hapca
RPRaluca Pascalau
Raluca Pascalau
Simona-Delia NicoaraSimona-Delia Nicoara
Simona-Delia Nicoara
Objective: This study aimed to evaluate the effectiveness of a visual rehabilitation method for anisometropic amblyopia that uses visual evoked potential (VEP) parameters and sound biofeedback to increase objectiveness. Design: an observational, case-controlled trial. Setting: Ophthalmology Clinic, Emergency County Hospital, Cluj-Napoca, Romania. Participants: Sixteen subjects with amblyopic anisometropia, aged 15–57, and sixteen controls, aged 24–33, were included. Interventions: Subjects were divided into two groups. The control group, composed of normal-vision subjects, and the amblyopic group received 10 training sessions. The rehabilitation program lasted 10 min, took place twice a week, and ran over five consecutive weeks. During each session, the subjects were asked to fixate on a target on the computer screen and were instructed to keep the fixation and maintain the sound of the biofeedback at high frequency. Main Measures: The study assessed the main visual parameters at baseline, after 10 sessions, and 1, 3, 6, and 12 months after treatment. Performance was evaluated by measuring visual acuity, contrast sensitivity, and reading velocity (words/minute). Results: In the experimental group, mean BCVA improved with two rows, which means an improvement in the LogMARLogMAR scale with an average of nine letters. These values tended to be maintained over time. Both groups showed better reading velocities after training, but this parameter has undergone large variability during follow-ups. Contrast sensitivity was also improved and stable. Conclusions: Visual rehabilitation with the Retimax Vision Trainer can improve visual performance in patients with amblyopia after the critical period, an improvement that is maintained in most cases for at least one year after treatment.

19 February 2026 in Diagnostics
Verified
Journal Article
Open access
PDF file
NINemes Iulia
Nemes Iulia
AȚAlexandru Țîpcu
Alexandru Țîpcu
ADAna-Maria Drăgan
Ana-Maria Drăgan
RPRaluca Pascalau
Raluca Pascalau
JBJennifer Bogdan
Jennifer Bogdan
MHMadalina Claudia Hapca
Madalina Claudia Hapca
Objectives: This study aimed to establish normative data for macular retinal thickness among Romanian children for two different spectral-domain optical coherence tomographs to establish if they are interchangeable and to compare gender-related differences. Methods: This analytical prospective study included 226 healthy children aged 3–17. A total of 113 eyes were examined with the Spectralis SD-OCT (Heidelberg Engineering) device and 113 with the Copernicus REVO SD-CT (Optopol Technology). Results: Central foveal and average macular thickness was measured and compared. Combining the two groups, measured with both devices, average measurements are as follows. The central foveal thickness was 203.87 ± 19.972 μm in males and 200.84 ± 21.891 μm in females for the left eye and 204.80 ± 21.516 μm and 199.74 ± 22.132 μm, respectively, for the right eye. While central foveal thickness was greater in males, the difference was not statistically significant (p = 0.288 for the left eye and p = 0.084 for the right eye). The average macular thickness was 256.94 ± 21.566 μm in males and 250.90 ± 23.488 μm in females for the left eye and 258.21 ± 21.30 μm and 249.70 ± 24.706 μm, respectively, for the right eye, showing significantly higher values in males (p = 0.048 for the left eye and p = 0.007 for the right eye). Significant inter-device variation was also observed across all OCT parameters (p < 0.001). Conclusions: This study provides normative data for macular thickness in healthy Romanian children for two spectral-domain optical coherence tomographs and may assist clinicians in interpreting paediatric OCT scans more accurately.

15 May 2026 in Vision
Verified
Journal Article
Open access
PDF file
LHLivia Hopirca
Livia Hopirca
AȚAlexandru Țîpcu
Alexandru Țîpcu
MHMadalina Claudia Hapca
Madalina Claudia Hapca
NINemes Iulia
Nemes Iulia
CLCosmina Teodora Lazăr
Cosmina Teodora Lazăr
Simona-Delia NicoaraSimona-Delia Nicoara
Simona-Delia Nicoara
Background: Children and teenagers use electronic devices daily, especially smartphones. The use of these devices exposes children and adolescents to excess blue light, which can alter the structures of the eye, especially the retina. As a protective mechanism, the macular region contains pigments represented by lutein, zeaxanthin, and meso-zeaxanthin. In this study, we aimed to analyze the relationship between the Macular Pigment Optical Density (MPOD) levels in the macula and the time spent on smartphones in children and adolescents. Methods: Fifty-seven children and teenagers aged between 8 and 18 were evaluated, with a total of 114 eyes. The patients included in the study were divided into two groups: those who spent less than two hours a day on the device and those who exceeded this period. To determine the amount of macular pigment, the Heterochromatic Flicker Photometry technique was used. Results: We found a statistically significant difference in screen time between weekdays and weekends in favor of the latter. We compared the different refractive categories with respect to pigment levels and screen time and found no significant differences between groups. When comparing the patients with respect to environment, we found a slight difference in macular pigmentation in the favor of rural areas and also in the screen time which was shorter in rural areas. We found a strong association at all levels between longer screen time (both weekdays and weekend) and lower macular pigment quantities for both eyes. When comparing the groups with more/less than 2 h of screen time, the MPOD was lower for both eyes in the group with over 2 h screen time. Conclusions: In this study we demonstrated that smartphone use is a risk factor leading to a decrease in MPOD in children and adolescents. The amount of lutein in the retina, brain and serum are correlated, therefore MPOD can be considered a natural biomarker of lutein and zeaxanthin levels in the body.