Background: In clinical genomics, sharing of rare genetic disease information between genetic databases and laboratories is essential to determine the pathogenic significance of variants to enable the diagnosis of rare genetic diseases. Significant concerns regarding data governance and security have reduced this sharing in practice. Blockchain could provide a secure method for sharing genomic data between involved parties and thus help overcome some of these issues.Objective: This study aims to contribute to the growing knowledge of the potential role of blockchain technology in supporting the sharing of clinical genomic data by describing blockchain-based dynamic consent architecture to support clinical genomic data sharing and provide a proof-of-concept implementation, called ConsentChain, for the architecture to explore its performance.Methods: The ConsentChain requirements were captured from a patient forum to identify security and consent concerns. The ConsentChain was developed on the Ethereum platform, in which smart contracts were used to model the actions of patients, who may provide or withdraw consent to share their data; the data creator, who collects and stores patient data; and the data requester, who needs to query and access the patient data. A detailed analysis was undertaken of the ConsentChain performance as a function of the number of transactions processed by the system.Results: We describe ConsentChain, a blockchain-based system that provides a web portal interface to support clinical genomic sharing. ConsentChain allows patients to grant or withdraw data requester access and allows data requesters to query and submit access to data stored in a secure off-chain database. We also developed an ontology model to represent patient consent elements into machine-readable codes to automate the consent and data access processes.Conclusions: Blockchains and smart contracts can provide an efficient and scalable mechanism to support dynamic consent functionality and address some of the barriers that inhibit genomic data sharing. However, they are not a complete answer, and a number of issues still need to be addressed before such systems can be deployed in practice, particularly in relation to verifying user credentials.

The advancement of communication and internet technology has brought risks to network security. Thus, Intrusion Detection Systems (IDS) was developed to combat malicious network attacks. However, IDSs still struggle with accuracy, false alarms, and detecting new intrusions. Therefore, organizations are using Machine Learning (ML) and Deep Learning (DL) algorithms in IDS for more accurate attack detection. This paper provides an overview of IDS, including its classes and methods, the detected attacks as well as the dataset, metrics, and performance indicators used. A thorough examination of recent publications on IDS-based solutions is conducted, evaluating their strengths and weaknesses, as well as a discussion of their potential implications, research challenges, and new trends. We believe that this comprehensive review paper covers the most recent advances and developments in ML and DL-based IDS, and also facilitates future research into the potential of emerging Artificial Intelligence (AI) to address the growing complexity of cybersecurity challenges.

Social media networks have grown exponentially over the last two decades, providing the opportunity for users of the internet to communicate and exchange ideas on a variety of topics. The outcome is that opinion mining plays a crucial role in analyzing user opinions and applying these to guide choices, making it one of the most popular areas of research in the field of natural language processing. Despite the fact that several languages, including English, have been the subjects of several studies, not much has been conducted in the area of the Arabic language. The morphological complexities and various dialects of the language make semantic analysis particularly challenging. Moreover, the lack of accurate pre-processing tools and limited resources are constraining factors. This novel study was motivated by the accomplishments of deep learning algorithms and word embeddings in the field of English sentiment analysis. Extensive experiments were conducted based on supervised machine learning in which word embeddings were exploited to determine the sentiment of Arabic reviews. Three deep learning algorithms, convolutional neural networks (CNNs), long short-term memory (LSTM), and a hybrid CNN-LSTM, were introduced. The models used features learned by word embeddings such as Word2Vec and fastText rather than hand-crafted features. The models were tested using two benchmark Arabic datasets: Hotel Arabic Reviews Dataset (HARD) for hotel reviews and Large-Scale Arabic Book Reviews (LARB) for book reviews, with different setups. Comparative experiments utilized the three models with two-word embeddings and different setups of the datasets. The main novelty of this study is to explore the effectiveness of using various word embeddings and different setups of benchmark datasets relating to balance, imbalance, and binary and multi-classification aspects. Findings showed that the best results were obtained in most cases when applying the fastText word embedding using the HARD 2-imbalance dataset for all three proposed models: CNN, LSTM, and CNN-LSTM. Further, the proposed CNN model outperformed the LSTM and CNN-LSTM models for the benchmark HARD dataset by achieving 94.69%, 94.63%, and 94.54% accuracy with fastText, respectively. Although the worst results were obtained for the LABR 3-imbalance dataset using both Word2Vec and FastText, they still outperformed other researchers’ state-of-the-art outcomes applying the same dataset.