Dr. Ta Yuan Chang is a Professor of Biochemistry and Cell Biology at the Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth. He earned a B.S. in Chemistry from National Taiwan University in 1967, followed by a Ph.D. in Biochemistry from the University of North Carolina, Chapel Hill in 1973. He then completed postdoctoral studies in Biochemistry at Washington University School of Medicine in St. Louis from 1973 to 1976. He began his career at Dartmouth Medical School, progressing from Assistant Professor (1976–1982) to Associate Professor (1982–1988), Professor (1988–2000), Professor and Chairman (2000–2008), and currently Professor (2008–present). His numerous awards and honors include an NIH Research Career Development Award (1982–1987), an NIH MERIT Award (1994–2004), an election as an AAAS Fellow (2011), and an election to the U.S. National Academy of Sciences (2021). He has also held various consultancies with Parke-Davis Pharmaceuticals, Pierre-Fabre Pharmaceutical Laboratories, and Chugai Pharmaceuticals, and served as a Review Board Member for the National Health Research Institutes in Taiwan (2002–2017). He and his wife Dr. Catherine C. Y. Chang together ( https://doi.org/10.1073/pnas.2205427119), lead a laboratory at Dartmouth that over four decades has advanced basic and translational research on cellular cholesterol metabolism, a process that plays a central role in health and disease.