Computer-assisted diagnosis is key for scaling up cervical cancer screening. However, current recognition algorithms perform poorly on whole slide image (WSI) analysis, fail to generalize for diverse staining and imaging, and show sub-optimal clinical-level verification. Here, we develop a progressive lesion cell recognition method combining low- and high-resolution WSIs to recommend lesion cells and a recurrent neural network-based WSI classification model to evaluate the lesion degree of WSIs. We train and validate our WSI analysis system on 3,545 patient-wise WSIs with 79,911 annotations from multiple hospitals and several imaging instruments. On multi-center independent test sets of 1,170 patient-wise WSIs, we achieve 93.5% Specificity and 95.1% Sensitivity for classifying slides, comparing favourably to the average performance of three independent cytopathologists, and obtain 88.5% true positive rate for highlighting the top 10 lesion cells on 447 positive slides. After deployment, our system recognizes a one giga-pixel WSI in about 1.5 min.

Terraces are the major land-use type of agriculture and support the main agricultural production in southeast and southwest China. However, due to smallholder farming, complex terrains, natural disasters and illegal land occupations, a light-weight and low cost dynamic monitoring of agricultural terraces has become a serious concern for smallholder production systems in the above area. In this work, we propose a small unmanned aerial vehicle (UAV) based multi-temporal image registration method that plays an important role in transforming multi-temporal images into one coordinate system and determines the effectiveness of the subsequent change detection for dynamic agricultural terrace monitoring. The proposed method consists of four steps: (i) guided image filtering based agricultural terrace image preprocessing, (ii) texture and geometric structure features extraction and combination, (iii) multi-feature guided point set registration, and (iv) feature points based image registration. We evaluated the performance of the proposed method by 20 pairs of aerial images captured from Longji and Yunhe terraces, China using a small UAV (the DJI Phantom 4 Pro), and also compared against four state-of-the-art methods where our method shows the best alignments in most cases.

We propose an audio-visual spatial-temporal deep neural network with: (1) a visual block containing a pre-trained 2D-CNN followed by a temporal convolutional network (TCN); (2) an aural block containing several parallel TCNs; and (3) a leader-follower attentive fusion block combining the audio-visual information. The TCN with large history coverage enables our model to exploit spatial-temporal information within a much larger window length (i.e., 300) than that from the baseline and state-of-the-art methods (i.e., 36 or 48). The fusion block emphasizes the visual modality while exploits the noisy aural modality using the inter-modality attention mechanism. To make full use of the data and alleviate over-fitting, the cross-validation is carried out on the training and validation set. The concordance correlation coefficient (CCC) centering is used to merge the results from each fold. On the test (validation) set of the Aff-Wild2 database, the achieved CCC is 0.463(0.469) for valence and 0.492(0.649) for arousal, which significantly outperforms the baseline method with the corresponding CCC of 0.200(0.210) and 0.190(0.230) for valence and arousal, respectively. The code is available at https://github.com/sucv/ABAW2.

Image registration plays an important role in military and civilian applications, such as natural disaster damage assessment, environmental monitoring, ground change detection and military damage assessment, etc. This work presents a new feature-based non-rigid image registration method. The main contributions of this work are: (i) a dynamic Gaussian component density is designed to better exploit available potential image information and provide sufficient inlier pairs for image transformation; (ii) a spatial structure preservation, which consists of an image transformation space curvature preservation and a local spatial structure constrain, is proposed to constrain the image transforming cost as well as the local structure of feature points during feature point set registration. The performances of the proposed method in multi-spectral natural images, lowaltitude aerial images and medical images against four types of nine state-of-the-art methods are tested where our method shows the best performances in most scenarios.

Symmetry lies at the heart of two-dimensional (2D) bioelectronics, determining material properties at the fundamental level. Breaking the symmetry allows emergent functionalities and effects. However, symmetry modulation in 2D bioelectronics and the resultant applications have been largely overlooked. Here, we devise an oxidized architectural MXene, referred to as oxidized MXene (OXene), that couples orbit symmetric breaking with inverse symmetric breaking to entitle the optimized interfacial impedance and Schottky-induced piezoelectric effects. The resulting OXene validates applications ranging from microelectrode arrays, gait analysis, active transistor matrix, and wireless signaling transmission, which enables high-fidelity signal transmission and reconfigurable logic gates. Furthermore, OXene interfaces were investigated in both rodent and porcine myocardium, featuring high-quality and spatiotemporally resolved physiological recordings, while accurate differentiated predictions, enabled via various machine learning pipelines.