Pingxi Wang

Pingxi Wang


Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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30 September 2025 in BMC Musculoskeletal Disorders
Verified
Journal Article
Open access
PDF file
YLYanlun Li
Yanlun Li
AAAsha Ajia
Asha Ajia
ZWZhongna Wu
Zhongna Wu
JFJianhui Fan
Jianhui Fan
MWMin Wu
Min Wu
PWPingxi Wang
Pingxi Wang
Knee replacement arthroplasty(KRA), including Total knee arthroplasty (TKA) and Unicompartmental knee arthroplasty (UKA), is the primary method for treating end-stage knee osteoarthritis (KOA). However, a history of previous knee surgeries (such as knee arthroscopy, ligament reconstruction, meniscectomy, high tibial osteotomy, etc.) may potentially affect functional recovery and complication risks after knee replacement. Although some studies have proposed such associations, the existing evidence remains controversial, and there is a lack of systematic quantitative analysis. This study aims to assess the impact of previous knee surgery on functional outcomes and complications following KRA. Following the PRISMA Guidelines, a systematic search was conducted in PubMed, Embase, Cochrane Library, and Web of Science databases up to August 4, 2024, for relevant studies. Demographic data, postoperative complications, and functional changes after primary KRA were evaluated in patients with and without a history of previous knee surgery. Statistical analysis of the included studies was performed using Stata 15.1 software. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of the studies. This meta-analysis included 28 studies with 703,103 patients (35,535 with a history of previous knee surgery and 667,568 primary KRA patients). Compared to the primary knee surgery group, the previous knee surgery group had significantly higher rates of prosthetic aseptic revision (RR(95%CI) = 1.45 (1.18–1.78)) (relative risk, RR; Confidence Interval, CI), infection (RR(95%CI) = 1.36 (1.11–1.67)), knee stiffness (RR(95%CI) = 1.73 (1.02–2.96)), and knee pain (RR(95%CI) = 1.21 (1.08–1.34)). However, there were no significant differences in changes in Knee Society Score (KSS) function (WMD(95%CI) = -0.51 (-1.73 to 0.72)) (weighted mean difference, WMD), KSS pain score (WMD(95%CI) = 0.41 (-2.97 to 3.79)), or other knee function scores. Patients with a history of previous knee surgery have a higher likelihood of prosthetic revision, a greater risk of surgical site infections or periprosthetic infections, and a significantly higher incidence of knee stiffness and knee pain following KRA.

12 December 2019 in PLOS ONE
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Journal Article
Open access
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DLDongdong Li
Dongdong Li
ZXZhenxiang XU
Zhenxiang XU
Riliang GuRiliang Gu
Riliang Gu
PWPingxi Wang
Pingxi Wang
DLDemar Lyle
Demar Lyle
Guoying WangGuoying Wang
Guoying Wang
[This corrects the article DOI: 10.1371/journal.pone.0223898.].

1 January 2025 in Endocrine Journal
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Journal Article
Open access
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JFJianhui Fan
Jianhui Fan
JLJunfeng Liu
Junfeng Liu
YLYanlun Li
Yanlun Li
AAAsha Ajia
Asha Ajia
PWPingxi Wang
Pingxi Wang
QHQin He
Qin He
Total ankle arthroplasty (TAA) is an effective treatment for end-stage ankle arthritis. However, the procedure is not without risks due to various factors, one of which is diabetes mellitus (DM). Currently, it remains uncertain whether diabetes is a risk factor for increased adverse outcomes and complications following total ankle arthroplasty. Therefore, this study aims to investigate the impact of diabetes on patients undergoing TAA. A systematic search was conducted for relevant studies published before December 2023 in PubMed, Embase, Cochrane Library, and Web of Science. The study assessed demographic data, postoperative complications, and functional outcomes of diabetic and non-diabetic patients following primary TAA. The Newcastle-Ottawa Scale (NOS) was used to evaluate study quality, and meta-analysis was performed using Stata 15.1, with forest plots generated for each variable. This meta-analysis included 14 studies involving 20,557 patients (3,847 with diabetes and 16,710 without). Compared to non-diabetic patients, those with diabetes had higher revision rates, postoperative infection rates, and 30-day readmission rates, longer hospital stays, and significantly different improvements in the SF-36 Physical Component Summary (PCS) score. Diabetic patients undergoing TAA are more likely to require revision surgery, face a higher risk of surgical site infections or periprosthetic joint infections, and experience increased hospital stay and 30-day readmission rates. These findings are crucial for guiding perioperative management of diabetic patients undergoing TAA and for explaining the associated surgical risks to patients.