Charalampos Varnava

Charalampos Varnava


Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 April 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
CVCharalampos Varnava
Charalampos Varnava
PWPhilipp Wiebringhaus
Philipp Wiebringhaus
Tobias HirschTobias Hirsch
Tobias Hirsch
ADAlexander Dermietzel
Alexander Dermietzel
MKMaximilian Kueckelhaus
Maximilian Kueckelhaus
Although microsurgical breast reconstruction represents a very interesting and rewarding field of plastic surgery, appropriate microsurgical training is not possible in every plastic surgery department. In this retrospective study, we present the learning curve of our plastic surgery department as a whole and of a single microsurgeon assessing breast reconstruction procedures with a deep inferior epigastric artery perforator (DIEP) flap between July 2018 and June 2021. The present study included 115 patients and 161 flaps. Cases were stratified into single DIEP/double DIEP groups and into early and late groups based on the flap order. Surgery times and postoperative complications were analyzed. Regarding the institution, the length of hospital stay was lower in the late group than in the early group (single 7.1 ± 1.8 vs. 6.3 ± 1.5 days, p = 0.019; double 8.5 ± 3.8 vs. 6.6 ± 1.4 days, p = 0.043). Apart from that, no statistically significant differences were found between the start and end of our study. In terms of the single surgeon, there was a significant improvement in the total surgery time (single 296.0 ± 78.7 vs. 227.5 ± 54.7 min, p = 0.018; double 448.0 ± 85.6 vs. 341.2 ± 43.1 min, p = 0.008), flap ischemia time (53.6 ± 15.1 vs. 40.9 ± 9.5 min, p = 0.007) and length of stay among the compared groups. There was no significant difference in flap loss rate or other complications between the early and late groups. Further performance of surgeries seemed to improve the surgeon’s skills as well as the overall experience of the medical institution.

22 May 2023 in Frontiers in Surgery
Verified
Journal Article
Open access
CVCharalampos Varnava
Charalampos Varnava
PWPhilipp Wiebringhaus
Philipp Wiebringhaus
DKDavid Kampshoff
David Kampshoff
THTobias Hirsch
Tobias Hirsch
MKMaximilian Kueckelhaus
Maximilian Kueckelhaus
Background: Autologous breast reconstruction is highly regarded in reconstructive surgery after mastectomy. DIEP flap reconstruction represents the gold standard for autologous breast reconstruction. The major advantages of DIEP flap reconstruction are its adequate volume, large vascular caliber and pedicle length. Despite reliable anatomy, there are procedures where the plastic surgeon's creativity is required, not only to shape the new breast, but also to overcome microsurgical challenges. An important tool in these cases is the superficial epigastric vein (SIEV).Methods: 150 DIEP flap procedures performed between 2018 and 2021 were retrospectively evaluated for SIEV use. Intraoperative and postoperative data were analyzed. Rate of anastomosis revision, total and partial flap loss, fat necrosis and donor site complications were evaluated.Results: In a total of 150 breast reconstructions with a DIEP flap performed in our clinic, the SIEV was used in 5 cases. The indication for using the SIEV was to improve the venous drainage of the flap or as a graft to reconstruct the main artery perforator. Among the 5 cases, no flap loss occurred.Conclusions: Use of the SIEV is an excellent method to expand the microsurgical options in breast reconstruction with DIEP flap surgery. It provides a safe and reliable procedure to improve venous outflow in cases of inadequate outflow from the deep venous system. The SIEV could also provide a very good option for fast and reliable application as an interposition device in case of arterial complications.

24 April 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
CVCharalampos Varnava
Charalampos Varnava
MBMiriam Bogusch
Miriam Bogusch
Sascha WellenbrockSascha Wellenbrock
Sascha Wellenbrock
Tobias HirschTobias Hirsch
Tobias Hirsch
PWPhilipp Wiebringhaus
Philipp Wiebringhaus
MKMaximilian Kueckelhaus
Maximilian Kueckelhaus
Background: Autologous breast reconstruction is a reliable solution for many patients after mastectomy. While this technique represents a standardized approach in many patients, patients with ptotic breasts may require a combination of procedures to achieve an aesthetically pleasing result. Methods: We reviewed the mastectomy and free-flap breast reconstruction procedures performed at our institution from 2018 to 2022 in patients with ptotic breasts. The technique used to address the ptosis was put in focus as we present the four strategies used by our reconstructive surgeons. We performed two different one-stage and two different two-stage procedures. The difference between the two-stage procedures was the way the nipple areola complex was treated (inferior dermal pedicle or free skin graft). The difference between the one-stage procedures was the time of execution of the mastopexy/breast reduction (before or after the mastectomy and autologous breast reconstruction). Results: The one-stage procedure was performed with a free NAC in three patients and with a pedicled NAC in five patients. The two-stage procedure was performed in seven patients, with six of them undergoing mastopexy before and one patient undergoing mastopexy after the bilateral mastectomy and autologous reconstruction. No flap loss or total loss of the nipple areola complex occurred. Partial NAC loss was observed in five breasts in the single-stage group without any occurrence in the double-stage group. Conclusions: While both one- and two-stage procedures were performed in a safe fashion with satisfactory results at our institution, larger trials are required to determine which procedure may yield the best possible outcomes. These outcomes should also include oncological safety and patient-reported outcomes.

9 September 2022 in Plastic and Reconstructive Surgery
Verified
Journal Article
Closed access
CVCharalampos Varnava
Charalampos Varnava
MKMaximilian Kueckelhaus
Maximilian Kueckelhaus
KHKamran Harati
Kamran Harati
PWPhilipp Wiebringhaus
Philipp Wiebringhaus
THTobias Hirsch
Tobias Hirsch

1 December 2023 in Plastic and Reconstructive Surgery - Global Open
Verified
Journal Article
Open access
CVCharalampos Varnava
Charalampos Varnava
PWPhilipp Md Wiebringhaus
Philipp Md Wiebringhaus
THTobias Hirsch
Tobias Hirsch
MKMaximilian Md Kueckelhaus
Maximilian Md Kueckelhaus