Valdir Gomes Barbosa-Júnior

Dr. Valdir Gomes Barbosa-Júnior


Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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29 December 2020 in Viruses
Verified
Journal Article
Open access
PDF file
Bruna MachadoBruna Machado
Bruna Machado
KHKatharine Valéria Saraiva Hodel
Katharine Valéria Saraiva Hodel
VBValdir Gomes Barbosa-Júnior
Valdir Gomes Barbosa-Júnior
Milena SoaresMilena Soares
Milena Soares
RBRoberto Badaro
Roberto Badaro
Diagnostic tests have been considered as the main alternative for the control of coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as a correct diagnosis allows for decision making when facing the disease, particularly as there is a lack of effective therapeutic protocols and vaccines. Thus, in this review, we summarized the main diagnostic approaches currently available for the diagnosis of SARS-CoV-2 infection in humans based on studies available in article databases. The tests can be organized into two main categories: nucleic acid-based tests, recommended for the initial detection of the virus, and serological tests, recommended for assessing the disease progression. The studies have shown that the performance of diagnostic methods depends on different factors, such as the type of samples and the characteristics of each assay. It was identified that the positivity of the tests is mainly related to the onset of symptoms. We also observed that point-of-care diagnoses are considered as one of the main trends in this area, due to the low-cost and simplicity of the assay; however, the analytical performance must be critically analyzed. Thus, the COVID-19 pandemic has highlighted the critical role of diagnostic technologies in the control of infectious diseases.