Density Peaks Clustering (DPC) is a density-based clustering algorithm that has the advantage of not requiring clustering parameters and detecting non-spherical clusters. The density peaks algorithm obtains the actual cluster center by inputting the cutoff distance and manually selecting the cluster center. Thus, the clustering center point is not selected on the basis of considering the whole data set. This paper proposes a method called G-KNN-DPC to calculate the cutoff distance based on the Gini coefficient and K-nearest neighbor. G-KNN-DPC first finds the optimal cutoff distance with Gini coefficient, and then the center point with the K-nearest neighbor. The automatic clustering center method can not only avoid the error that a cluster detects two center points but also effectively solve the traditional DPC algorithm defect that cannot handle complex data sets. Compared with DPC, Fuzzy C-Means, K-means, KDPC and DBSCAN, the proposed algorithm creates better clusters on different data sets.

MRI segmentation is critically important for clinical study and diagnosis. Existing methods based on soft clustering have several drawbacks, including low accuracy in the presence of image noise and artifacts, and high computational cost. In this paper, we introduce a new formulation of the MRI segmentation problem as a kernel-based intuitionistic fuzzy C-means (KIFCM) clustering problem and propose a new DNA-based genetic algorithm to obtain the optimal KIFCM clustering. While this algorithm searches the solution space for the optimal model parameters, it also obtains the optimal clustering, therefore the optimal MRI segmentation. We perform empirical study by comparing our method with six state-of-the-art soft clustering methods using a set of UCI (University of California, Irvine) datasets and a set of synthetic and clinic MRI datasets. The preliminary results show that our method outperforms other methods in both the clustering metrics and the computational efficiency.