Laleh Golestanirad

Prof. Dr. Laleh Golestanirad


Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2019 in NeuroImage
Verified
Journal Article
Closed access
LGLaleh Golestanirad
Laleh Golestanirad
JKJohn Kirsch
John Kirsch
GBGiorgio Bonmassar
Giorgio Bonmassar
SDSean Downs
Sean Downs
BEBehzad Elahi
Behzad Elahi
JPJulie Pilitsis
Julie Pilitsis

13 May 2019 in NeuroImage
Verified
Journal Article
Closed access
EKEhsan Kazemivalipour
Ehsan Kazemivalipour
BKBoris Keil
Boris Keil
AVAlireza Vali
Alireza Vali
SRSunder Rajan
Sunder Rajan
BEBehzad Elahi
Behzad Elahi
LGLaleh Golestanirad
Laleh Golestanirad

1 January 2019 in IEEE Transactions on Microwave Theory and Techniques
Verified
Journal Article
Closed access
LGLaleh Golestanirad
Laleh Golestanirad
LALeonardo Angelone
Leonardo Angelone
JKJohn Kirsch
John Kirsch
SDSean Downs
Sean Downs
BKBoris Keil
Boris Keil
LWLawrence L. Wald
Lawrence L. Wald
Patients with implanted medical devices such as deep brain stimulation or spinal cord stimulation are often unable to receive magnetic resonance imaging (MRI). This is because, once the device is within the radio frequency (RF) field of the MRI scanner, electrically conductive leads act as antenna, amplifying the RF energy deposition in the tissue and causing possible excessive tissue heating. Here, we propose a novel concept in lead design in which 40-cm lead wires are coated with a ~1.2-mm layer of high dielectric constant material (155 <; ε r <; 250) embedded in a weakly conductive insulation (σ = 20 S/m). The technique called high-dielectric capacitive bleeding of current (CBLOC) works by forming a distributed capacitance along the lengths of the lead, efficiently dissipating RF energy before it reaches the exposed tip. Measurements during RF exposure at 64 and 123 MHz demonstrated that CBLOC leads generated 20-fold less heating at 1.5 T and 40-fold less heating at 3 T compared to control leads. Numerical simulations of RF exposure at 297 MHz (7 T) predicted a 15-fold reduction in specific absorption rate of RF energy around the tip of CBLOC leads compared to control leads.

28 August 2020 in Journal of Magnetic Resonance Imaging
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Journal Article
Closed access
PDF file
BBBhumi Bhusal
Bhumi Bhusal
BNBach T. Nguyen
Bach T. Nguyen
PSPia P. Sanpitak
Pia P. Sanpitak
JVJasmine Vu
Jasmine Vu
BEBehzad Elahi
Behzad Elahi
LGLaleh Golestanirad
Laleh Golestanirad

7 August 2019 in PLOS ONE
Verified
Journal Article
Open access
PDF file
LGLaleh Golestanirad
Laleh Golestanirad
EKEhsan Kazemivalipour
Ehsan Kazemivalipour
BKBoris Keil
Boris Keil
SDSean Downs
Sean Downs
JKJohn Kirsch
John Kirsch
LWLawrence L. Wald
Lawrence L. Wald
Patients with deep brain stimulation (DBS) implants can significantly benefit from magnetic resonance imaging (MRI), however access to MRI is restricted in these patients because of safety concerns due to RF heating of the leads. Recently we introduced a patient-adjustable reconfigurable transmit coil for low-SAR imaging of DBS at 1.5T. A previous simulation study demonstrated a substantial reduction in the local SAR around single DBS leads in 9 unilateral lead models. This work reports the first experimental results of temperature measurement at the tips of bilateral DBS leads with realistic trajectories extracted from postoperative CT images of 10 patients (20 leads in total). A total of 200 measurements were performed to record temperature rise at the tips of the leads during 2 minutes of scanning with the coil rotated to cover all accessible rotation angles. In all patients, we were able to find an optimum coil rotation angle and reduced the heating of both left and right leads to a level below the heating produced by the body coil. An average heat reduction of 65% was achieved for bilateral leads. When considering each lead alone, an average heat reduction of 80% was achieved. Our results suggest that reconfigurable coil technology introduces a promising approach for imaging of patients with DBS implants.

2 November 2019 in Magnetic Resonance in Medicine
Verified
Journal Article
Closed access
PDF file
LGLaleh Golestanirad
Laleh Golestanirad
EKEhsan Kazemivalipour
Ehsan Kazemivalipour
DLDavid Lampman
David Lampman
HHHideta Habara
Hideta Habara
EAErgin Atalar
Ergin Atalar
JKJohn Kirsch
John Kirsch