Christos Agalianos

Dr. Christos Agalianos

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Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 March 2018 in Translational Gastroenterology and Hepatology
Verified
Journal Article
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CAChristos Agalianos
Christos Agalianos
IPIoannis Passas
Ioannis Passas
ISIoannis Sideris
Ioannis Sideris
DDDemetrios Davides
Demetrios Davides
CDChristos Dervenis
Christos Dervenis
Pancreatic pseudocysts (PPs) present a challenging problem for physicians dealing with pancreatic disorders. Their management demands the co-operation of surgeons, radiologists and gastroenterologists. Historically, they have been treated either conservatively or surgically, with acceptable rates of complications and recurrence. However, recent advances in radiology and endoscopy, have leaded physicians to implement percutaneous and endoscopic drainage (ED) into their treatment algorithms. Moreover, laparoscopic surgery, with its advantages, has become an attractive alternative choice when surgical drainage (SD) is required. The aim of this review is to summarize the main diagnostic and therapeutic tools in the management of pseudocysts and to present the main studies that compare the three different types of pseudocyst drainage.


28 February 2023 in Current Oncology
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Journal Article
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DMDimitrios K. Manatakis
Dimitrios K. Manatakis
MTMaria Tzardi
Maria Tzardi
John SouglakosJohn Souglakos
John Souglakos
JTJohn Tsiaoussis
John Tsiaoussis
CAChristos Agalianos
Christos Agalianos
EXEvaghelos Xynos
Evaghelos Xynos
Background: Colon cancer surgery is a complex clinical pathway and traditional quality metrics may exhibit significant variability between hospitals and healthcare providers. The Textbook Outcome (TO) is a composite quality marker capturing the fraction of patients, in whom all desired short-term outcomes of care are realised. The aim of the present study was to assess the TO in a series of non-metastatic colon cancer patients treated with curative intent, with emphasis on long-term survival. Methods: Stage I–III colon cancer patients, who underwent curative colectomy following the Complete Mesocolic Excision principles, were retrospectively identified from the institutional database. TO was defined as (i) hospital survival, (ii) radical resection, (iii) no major complications, (iv) no reintervention, (v) no unplanned stoma and (vi) no prolonged hospital stay or readmission. Results: In total, 128 patients (male 61%, female 39%, mean age 70.7 ± 11.4 years) were included in the final analysis. Overall, 60.2% achieved a TO. The highest rates were observed for “hospital survival” and “no unplanned stoma” (96.9% and 97.7%), while the lowest rates were for “no major complications” and “no prolonged hospital stay” (69.5% and 75%). Older age, left-sided resections and pT4 tumours were factors limiting the chances of a TO. The 5-year overall and 5-year cancer-specific survival were significantly better in the TO versus non-TO subgroup (81% vs. 59%, p = 0.009, and 86% vs. 65%, p = 0.02, respectively). Conclusions: Outcomes in colon cancer surgery may be affected by patient-, doctor- and hospital-related factors. TO represents those patients who achieve the optimal perioperative results, and is furthermore associated with improved long-term cancer survival.

1 February 2018 in Journal of Laparoendoscopic & Advanced Surgical Techniques
Verified
Journal Article
Closed access
NGNIKOLAOS GOUVAS
NIKOLAOS GOUVAS
PGPanagiotis A. Georgiou
Panagiotis A. Georgiou
CAChristos Agalianos
Christos Agalianos
GTGeorgios Tzovaras
Georgios Tzovaras
PTParis Tekkis
Paris Tekkis
EXEvaghelos Xynos
Evaghelos Xynos
Introduction: Laparoscopy for rectal cancer is a challenge as it presents many technical difficulties and requires high level of expertise. That is the reason for the high conversion rate. Reports on outcomes of converted cases after laparoscopic rectal resection for cancer are conflicting. Aim: The present meta-analysis compares short- and long-term outcomes between converted rectal cancer cases with both open and laparoscopically completed cases. Method: All studies reporting on outcomes separately for the converted cases were reviewed systematically. Main outcomes were intraoperative complications, procedure duration, short-term mortality and morbidity, length of stay, local recurrence, number of lymph nodes retrieved, and distant metastases. Quality assessment and data extraction were performed independently by 3 reviewers. Results: Fourteen studies were eligible for analysis, including 10,845 patients. Overall conversion rate was 11.9%. Converted cases had significantly longer duration, hospital stay, and higher rates of wound infection compared with laparoscopic cases. All other outcomes had no difference. When compared with open cases, conversions displayed longer operative times, but there was no other significant difference in the short- or long-term outcomes. Conclusion: Converted cases seem to have some short-term unfavorable outcomes. Further retrospective analysis of big registries will be helpful for further investigation of converted cases.

1 January 2015 in Oncology Letters
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Journal Article
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EZEfstratios Zouros
Efstratios Zouros
DMDimitrios K. Manatakis
Dimitrios K. Manatakis
SDSpiros Delis
Spiros Delis
CAChristos Agalianos
Christos Agalianos
CTCharina Triantopoulou
Charina Triantopoulou
CDChristos Dervenis
Christos Dervenis
The present study describes the case of a 24‑year‑old patient who presented with obstructive jaundice and weight loss, and was diagnosed with pancreatoblastoma (PB). Abdominal imaging studies revealed a heterogenous lesion of the pancreatic head with dilatation of the common bile duct. The patient underwent pancreaticoduodenectomy, however, three months after surgery multiple liver and bone metastases were identified on follow-up computed tomography scans. Despite treatment with four cycles of systemic chemotherapy and five courses of radiofrequency ablation, the patient succumbed due to tumour dissemination 13 months after initial diagnosis. PB is a malignant tumour of the pancreas that typically occurs in the pediatric population. The aim of the present study was to highlight the aggressive behavior of this rare clinical entity, focusing on the pitfalls of pre‑operative diagnosis and the lack of management strategy guidelines in adults. Preoperative diagnosis of PB based on radiographic features may be difficult, as the imaging characteristics are non-specific. Furthermore, cytology may also be misleading, as the neoplasm consists of multiple cell lines (acinar, ductal and neuroendocrine cells) and diagnosis depends largely on the identification of the distinctive histological characteristic of squamoid corpuscles, which present as nests of flattened cells with a squamous appearance. Despite the use of surgical resection and adjuvant chemoradiotherapy for the treatment of this malignancy, its aggressive nature means that PB is associated with a poor prognosis in adult patients.

4 September 2013 in Case Reports in Anesthesiology
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Journal Article
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DMDimitrios K. Manatakis
Dimitrios K. Manatakis
NSNikolaos Stamos
Nikolaos Stamos
CAChristos Agalianos
Christos Agalianos
MKMichail Athanasios Karvelis
Michail Athanasios Karvelis
MGMichael Gkiaourakis
Michael Gkiaourakis
DDDemetrios Davides
Demetrios Davides
We present two cases of patients who reported quadriceps femoris weakness and hypoesthesia over the anterior thigh after an inguinal hernia repair under transversus abdominis plane (TAP) block. Transient femoral nerve palsy is the result of local anesthetic incorrectly injected between transversus abdominis muscle and transversalis fascia and pooling around the femoral nerve. Although it is a minor and self-limiting complication, it requires overnight hospital stay and observation of the patients. Performing the block under ultrasound guidance and injecting the least volume of local anesthetic required are ways of minimizing its incidence.