Osteointegrative dental implants are widely used in implantology for their well-known excellent performance once implanted in the host. Remarkable bacterial colonization along the transgingival region may result in a progressive loss of adhesion at gum-implant interface and an increase of the bone area exposed to pathogens. This phenomenon may negatively effect the osteointegration process and cause, in the most severe cases, implant failure. The presence of bacteria at implant site affect the growth of new bone tissue and consequently, the achievement of a mechanically stable bone-implant interface, key parameters for a suitable implant osteointegration. In the present work, a novel surface treatment has been developed and optimized in order to convert the amorphous titanium oxide in a crystalline layer enriched in anatase capable of providing not only antibacterial properties but also of stimulating the precipitation of apatite when placed in simulated body fluid. The collected data have shown that the tested treatment results in a crystalline anatase-type titanium oxide layer able to provide a remarkable decrease in bacterial attachment without negatively effecting cell metabolic activity. In conclusion, the surface modification treatment analyzed in the present study might be an elegant way to reduce the risk of bacterial adhesion and increase the lifetime of the transgingival component in the osteointegrated dental implant.
1 September 2013 in Construction and Building Materials
Titanium biomaterials are widely employed to produce medical components, such as hip and knee-joint prostheses, bone plates and screws, dental implants, pacemaker cases, surgical equipment, etc. Their diffusion is ascribed to the broad spectrum of optimal mechanical and surface properties, such as the corrosion resistance and correlated low ionic release, the biocompatibility, and especially, the enhanced osseointegration that can be achieved by surface modifications, particularly by suitable anodizing treatments. This review is intended to provide a survey of the wide class of anodic oxidation treatments on titanium, focusing on the oxide structures, morphologies, and compositions that best apply to the variegated fields of titanium applications.
The paper proposes a comprehensive and operational definition of Sustainable Food Packaging (SFP). Sustainability is a multifaceted concept, yet most SFP conversations decline it as a mere material substitution issue. The efforts of regulators, packaging producers, food companies, and consumers towards the design and adoption of SFP products are likely to fail without a common understanding of the multiple means by which food packaging contributes to sustainability. Based on an extensive literature review and the contributions of SFP innovation experts, the paper builds a Food Packaging Sustainability Framework (FPSF) that encompasses the three main dimensions of SFP, namely environmental conservation, food safety, and social value, and operationalizes them in terms of objectives and activable levers. The framework can be used as a tool to search and evaluate food packaging products, a conceptual guide for SFP design, and a narrative platform for coordinating supply chain actors, including consumers. The experimental activities applying FPSF gathered the different actors in the supply chain to jointly adopt the integrated model that distributes environmental, social, and economic benefits along the entire production chain.