Among traditional cardiovascular diseases (CVD) risk factors, obesity has become a major research target due to its epidemic prevalence1 1 GBD 2017 Risk Factor Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1923-94. http://dx.doi.org/10.1016/S0140-6736(18)32225-6. PMid:30496105. http://dx.doi.org/10.1016/S0140-6736(18)... . Another independent risk factor for CVD is psychological stress2 2 Huang CJ, Webb HE, Zourdos MC, Acevedo EO. Cardiovascular reactivity, stress, and physical activity. Front Physiol. 2013;4:314. http://dx.doi.org/10.3389/fphys.2013.00314. PMid:24223557. http://dx.doi.org/10.3389/fphys.2013.003... . Acute mental stress tasks have been used as a laboratory models to examine cardiovascular response to psychological stress3 3 Carroll D, Ginty AT, Der G, Hunt K, Benzeval M, Phillips AC. Increased blood pressure reactions to acute mental stress are associated with 16-year cardiovascular disease mortality. Psychophysiology. 2012;49(10):1444-8. http://dx.doi.org/10.1111/j.1469-8986.2012.01463.x. PMid:22958235. http://dx.doi.org/10.1111/j.1469-8986.20... 4 Steptoe A, Kivimaki M, Lowe G, Rumley A, Hamer M. Blood pressure and fibrinogen responses to mental stress as predictors of incident hypertension over an 8-year period. Ann Behav Med. 2016;50(6):898-906. http://dx.doi.org/10.1007/s12160-016-9817-5. PMid:27401000. http://dx.doi.org/10.1007/s12160-016-981... -5 5 Carroll D, Phillips AC, Der G, Hunt K, Benzeval M. Blood pressure reactions to acute mental stress and future blood pressure status: data from the 12-year follow-up of the West of Scotland Study. Psychosom Med. 2011;73(9):737-42. http://dx.doi.org/10.1097/PSY.0b013e3182359808. PMid:22021460. http://dx.doi.org/10.1097/PSY.0b013e3182... . Evidence has suggested that the association between systolic blood pressure (SBP) reactivity to mental stress and increased risk for future cardiovascular events is independent of baseline BP values6 6 Chida Y, Steptoe A. Greater cardiovascular responses to laboratory mental stress are associated with poor subsequent cardiovascular risk status: a meta-analysis of prospective evidence. Hypertension. 2010;55(4):1026-32. http://dx.doi.org/10.1161/HYPERTENSIONAHA.109.146621. PMid:20194301. http://dx.doi.org/10.1161/HYPERTENSIONAH... .