Transfer learning (TL) has been proven to be one of the most significant techniques for cross-subject classification in electroencephalogram (EEG)-based brain-computer interfaces (BCI). Hence, it is widely used to address the challenges of cross-session and cross-subject variability with more accurate intention prediction. In this case, TL utilizes knowledge (signal features) in the source domain(s) to improve the classification in the target domain. However, current existing transfer learning approaches on EEG-based BCI are mostly limited to two-class cross-subject classification problems, while multi-class problems are only implemented with a focus on within-subject classification due to the complexity of multi-class cross-subject classification problems. In this paper, we first extended the transfer learning approaches to a multi-class cross-subject scenario, then investigated the reason for transfer learning performance being poor in multi-class cross-subject classification. Secondly, we address the challenge of significant sessional and subject-to-subject variations originating from both known and unknown factors. It is discovered that such variations have a massive influence on the classification because of the negative transfer (NT) across domains. Based on this discovery, we propose a multi-class transfer learning approach based on multi-source manifold feature transfer learning (MMFT) framework and an enhanced version to minimize the effects of NT. The proposed multi-class transfer learning approach extends the existing MMFT to multi-class cases. Then enhanced multi-class MMFT firstly searches for domains with high transferability and selects only the best combination among source domains (SD), then utilize the best-selected combination of domains for transfer learning. Experimental results illustrate that the proposed multi-class MMFT can be employed in the cross-subject classification of both three-class and four-class problems. Experimental results also demonstrated that the enhanced multi-class MMFT could effectively minimize the effect of negative transfer and significantly increase the prediction rates across individual target domains (TD). The highest classification accuracy (CA) of 98% is obtained by the enhanced multi-class MMFT.

Transfer learning (TL) utilizes knowledge from the source domain (SD) to enhance the classification rate in the target domain (TD). It has been widely used to address the challenge of sessional and inter-subject variations in electroencephalogram (EEG)-based brain–computer interfaces (BCIs). However, utilizing knowledge from a combination of both related and non-related sources can significantly deteriorate the classification performance across individual target domains, resulting in a negative transfer (NT). Hence, NT becomes one of the most significant challenges for transfer learning algorithms. Notably, domain selection techniques have been developed to address the challenge of NT emerging from the transfer of knowledge from non-related sources. However, existing domain selection approaches iterate through domains and remove a single low-beneficial domain at a time, which can massively affect the classification performance in each iteration since SDs respond differently to other sources. In this paper, we compare domain selection techniques for a multi-source manifold feature transfer learning (MMFT) framework to address the challenge of NT and then evaluate the effect of beneficial and non-beneficial sources on TL performance. To evaluate the effect of low-beneficial and high beneficial sources on TL performance, some commonly used domain selection methods are compared, namely, domain transferability estimation (DTE), rank of domain (ROD), label similarity analysis, and enhanced multi-class MMFT (EMC-MMFT), using the same multi-class cross-session and cross-subject classification problems. The experimental results demonstrate the superiority of the EMC-MMFT algorithm in terms of minimizing the effect of NT. The highest classification accuracy (CA) of 100% is achieved when optimal combinations of high beneficial sources are selected for two-class SSMVEP problems, while the highest CAs of 98% and 87% are achieved for three- and four-class SSMVEP problems, respectively. The highest CA of 98% is achieved for two-class MI classification problems, while the highest CAs of 90% and 71.5% are obtained for three- and four-class MI problems, respectively.