Objectives: To review literature on the link between depression and anxiety in patients suffering from tinnitus. Method: A systematic review of published English-language literature was performed using PubMed, Ovid, and Cochrane databases. Results: Of the 56 eligible abstracts 15 were chosen to be included in the review. All articles showed an association of depression and anxiety in tinnitus patients. Conclusions: Because of the strong association between tinnitus, depression, and anxiety- all tinnitus patients should be screened for psychiatric disorders. Treatment for these complex conditions should involve a multidisciplinary team with cognitive behavioral therapy and possible pharmacological therapy.

A perilymphatic fistula (PLF) is an abnormal communication between the perilymph-filled inner ear and the middle ear cavity, mastoid, or intracranial cavity. A PLF most commonly forms when the integrity of the oval or round window is compromised, and it may be trauma-induced or may occur with no known cause (idiopathic). Controversy regarding the diagnosis of idiopathic PLF has persisted for decades, and the presenting symptoms may be vague. However, potential exists for this condition to be one of the few etiologies of dizziness, tinnitus, and hearing loss that can be treated surgically. The aim of this review is to provide an update on classification, diagnosis, and treatment of PLF. Particular attention will be paid to idiopathic PLF and conditions that may have a similar presentation, with subsequent information on how best to distinguish them. Novel diagnostic criteria for PLF and management strategy for PLF and PLF-like symptoms is presented.

Objectives: (1) Perform a meta‐analysis of the available data on the outcomes of CyberKnife radiosurgery for treatment of vestibular schwannomas (VSs) in the published English‐language literature and (2) evaluate the collective outcomes of CyberKnife treatment with respect to tumor control and hearing preservation.Data Sources: A thorough literature search of published English‐language articles was performed in the PubMed, Ovid, and Cochrane databases.Review Methods: A database search was conducted with the keywords “CyberKnife” and “vestibular schwannoma” or “acoustic neuroma.” A total of 25 papers were found and reviewed. Data were extracted for patient demographics, number of patients with neurofibromatosis type 2, pretreatment hearing status, tumor size, margin dose, and follow‐up duration. The primary outcome variables evaluated were tumor control and hearing preservation.Results: After careful review of the published articles, 11 papers reported data on outcomes of CyberKnife treatment for VS and were included in the analysis, comprising 800 patients studied during 1998 to 2012. The reported mean tumor volume ranged from 0.02 to 19.8 cm³, and the follow‐up duration ranged from 6 to 120 months. Margin dose varied from 14 to 25 Gy. The collective mean tumor control rate was 96.3% (95% CI: 94.0%‐98.5%). The collective hearing preservation rate was 79.1% (95% CI: 71.0%‐87.3%) in 427 patients with measurable hearing.Conclusion: Clinical data on outcomes of CyberKnife radiosurgery for treatment of VSs are sparse and primarily limited to single‐institution analyses, with considerable variation in tumor volume and follow‐up time. This meta‐analysis not only provides an in‐depth analysis of available data in the literature but also reviews reported outcomes and complications.