Tsvetomira Ivanova is a versatile, dedicated, curious, and motivated researcher with more than 20 years of experience in microbiology, immunology biotechnology, genetics, and molecular and cell biology in yeast, bacteria, and human cells. This experience is reflected by 10 peer-reviewed publications, with an h-index 6. She received a degree in Gene and Cell Engineering and in Industrial Biotechnology in 2002, and another in Biomedicine in 2008. She was awarded her PhD in Biomedicine from the Universitat Pompeu Fabra, Spain in the area of cell cycles, where she was interested in studying the regulation of the G1-to-S phase transition in yeast. As a Postdoctoral fellow in CRG, Spain, her focus was on understanding Topo II function and the formation and resolution of anaphase chromatin bridges during chromosome segregation in budding yeast as a potential source of genomic instability. Since 2020, as a researcher and an assistant professor at Medical University of Plovdiv, Bulgaria, she conducts practical lessons for first year students on Medical Biology. Her research interests are directed to investigate and to reveal the link between carcinogenesis, inflammation, and autophagy as consequences of hypoxia and to understand their relationship and role in tumor cell therapy resistance in 2D and 3D models in colorectal cancer. Thus, new molecular signatures/biomarkers and miRNAs can be Identified as an innovative strategy for sensitizing tumor cells to therapeutic agents in CRC.