Machine learning (ML) and artificial intelligence (AI) are widely applied in many disciplines including medicine. Pattern recognition or automatization has been successfully implemented in various field studies. Similarly, multiple efforts have been made in medicine to implement AI/ML technology to solve medical problems, for example, for automating osteoporosis detection. In general, the success of AI/ML technology is highly dependent on the amount of available data, especially during the training stage. Feature generation is a common technique that allows the manipulation of available data for the training stages. This paper aims to study the feasibility of adopting signal-processing techniques for feature generation in medical image processing. Signal attributes from signal processing workflow were adopted and applied to image processing of CT and DEXA scanning data to differentiate between normal and osteoporotic bone. Five attributes, namely amplitude, frequency, instantaneous phase, roughness, and first derivative or contrast attributes, have been tested. An attribute index number is formulated to indicate the attribute’s strength at the selected region of interest (ROI). A case study applying these attributes to the CNN model is presented. More than five hundred CT scan images of normal and osteoporosis bone were used during the training stage to test classification performance with and without developed attributes as an input. From the ten selected CT scan images used to test the CNN model, 90% were well predicted in the scenario only utilizing the grayscale as input. However, when including the developed attributes, the CNN can predict all the images well (100% were well predicted). In conclusion, the technique adopted from the signal-processing technique has the potential to enhance feature generation in image processing, whereby the results can be used for the early application of AI/ML in osteoporosis identification. Further research testing this proposed method in different image modalities needs to be conducted to verify the robustness of the proposed method.

Background: Hypospadias remains the most prevalent congenital abnormality in boys worldwide. However, the limited infrastructure and number of pediatric urologists capable of diagnosing and managing the condition hinder the management of hypospadias in Indonesia. The use of artificial intelligence and image recognition is thought to be beneficial in improving the management of hypospadias cases in Indonesia. Objective: We aim to develop and validate a digital pattern recognition system and a mobile app based on an artificial neural network to determine various parameters of hypospadias. Methods: Hypospadias and normal penis images from an age-matched database will be used to train the artificial neural network. Images of 3 aspects of the penis (ventral, dorsal, and lateral aspects, which include the glans, shaft, and scrotum) will be taken from each participant. The images will be labeled with the following hypospadias parameters: hypospadias status, meatal location, meatal shape, the quality of the urethral plate, glans diameter, and glans shape. The data will be uploaded to train the image recognition model. Intrarater and interrater analyses will be performed, using the test images provided to the algorithm. Results: Our study is at the protocol development stage. A preliminary study regarding the system’s development and feasibility will start in December 2022. The results of our study are expected to be available by the end of 2023. Conclusions: A digital pattern recognition system using an artificial neural network will be developed and designed to improve the diagnosis and management of patients with hypospadias, especially those residing in regions with limited infrastructure and health personnel.

Heart disease is the leading cause of death in Indonesia based on 2010 Hospital Information System (SIRS) Report. Early detection and treatment of heart disease will reduce the patient mortality rate. Therefore, implementation of artificial neural networks (ANN) technique in diagnosing heart disease have been widely used and reached good accuracy. Beside of that, there are disadvantages in implementation of ANN technique, such as a long training process, many parameters have to be tuned, the obtained solution potentially get stuck in local minima, and activation function must be differentiable. We implemented Extreme Learning Machine (ELM) which is fast, simple tuning, and better generalization model learning algorithm. It has better performance than backpropagation ANN, Support Vector Machine (SVM), and decision tree. The results indicate that the ELM model has potentially implemented to help medical professional in diagnosing heart disease.

Cervical cancer ranks among the top causes of cancer-related deaths in women globally. Early detection is vital for improving patient survival rates. The multiclass classification of cervical cell images presents challenges primarily due to the notable variations in cell sizes across different classes. Conventional AI methods for diagnosing cervical cancer often rely on image-resizing techniques that overlook crucial features like relative cell dimensions, which impairs the models' ability to distinguish between classes effectively. This paper presents a novel AI-driven approach that employs constant padding to maintain the natural size differences among cells. Our method utilizes deep learning for both feature extraction and multiclass classification. We assessed the method using the publicly accessible SIPaKMeD dataset. Experimental findings indicate that our approach surpasses traditional image-resizing methods, especially in classes that are more challenging to predict. This strategy highlights AI's potential to improve cervical cancer diagnosis, offering a more precise and dependable tool for early detection. A reliable and precise AI model for diagnosing cervical cancer is crucial for promoting widespread screening and ensuring timely and effective treatment, which can ultimately lower mortality rates. By aiding early and accurate diagnosis, this approach aligns with global health efforts to alleviate the burden of cancer and other diseases, especially in areas with limited access to advanced healthcare services facilities.