Philippa Clarke

Prof. Dr. Philippa Clarke

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Research Focus & Metrics

Academic Career Length

26Years (2001-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 August 2008 in Journal of Epidemiology and Community Health
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Journal Article
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PCPhilippa Clarke
Philippa Clarke
Objective: The use of multilevel modelling with data from population-based surveys is often limited by the small number of cases per level-2 unit, prompting many researchers to use single-level techniques such as ordinary least squares regression. Design: Monte Carlo simulations are used to investigate the effects of data sparseness on the validity of parameter estimates in two-level versus single-level models. Setting: Both linear and non-linear hierarchical models are simulated in order to examine potential differences in the effects of small group size across continuous and discrete outcomes. Results are then compared with those obtained using disaggregated techniques (ordinary least squares and logistic regression). Main results: At the extremes of data sparseness (two observations per group), the group level variance components are overestimated in the two-level models. But with an average of only five observations per group, valid and reliable estimates of all parameters can be obtained when using a two-level model with either a continuous or a discrete outcome. In contrast, researchers run the risk of Type I error (standard errors biased downwards) when using single-level models even when there are as few as two observations per group on average. Bias is magnified when modelling discrete outcomes. Conclusions: Multilevel models can be reliably estimated with an average of only five observations per group. Disaggregated techniques carry an increased risk of Type I error, even in situations where there is only limited clustering in the data.

2 July 2008 in American Journal of Epidemiology
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Journal Article
Open access
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PCPhilippa Clarke
Philippa Clarke
JAJennifer A. Ailshire
Jennifer A. Ailshire
MBMichael Bader
Michael Bader
JMJeffrey D. Morenoff
Jeffrey D. Morenoff
JHJames S. House
James S. House
Research on the effects of the built environment in the pathway from impairment to disability has been largely absent. Using data from the Chicago Community Adult Health Study (2001–2003), the authors examined the effect of built environment characteristics on mobility disability among adults aged 45 or more years (n = 1,195) according to their level of lower extremity physical impairment. Built environment characteristics were assessed by using systematic social observation to independently rate street and sidewalk quality in the block surrounding each respondent's residence in the city of Chicago (Illinois). Using multinomial logistic regression, the authors found that street conditions had no effect on outdoor mobility among adults with only mild or no physical impairment. However, among adults with more severe impairment in neuromuscular and movement-related functions, the difference in the odd ratios for reporting severe mobility disability was over four times greater when at least one street was in fair or poor condition (characterized by cracks, potholes, or broken curbs). When all streets were in good condition, the odds of reporting mobility disability were attenuated in those with lower extremity impairment. If street quality could be improved, even somewhat, for those adults at greatest risk for disability in outdoor mobility, the disablement process could be slowed or even reversed.

1 November 2010 in Health & Place
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Journal Article
Closed access
PCPhilippa Clarke
Philippa Clarke
JAJennifer Ailshire
Jennifer Ailshire
RMRobert Melendez
Robert Melendez
MBMichael Bader
Michael Bader
JMJeffrey Morenoff
Jeffrey Morenoff

1 September 2009 in Maturitas
Verified
Journal Article
Closed access
PCPhilippa Clarke
Philippa Clarke
ENEls R. Nieuwenhuijsen
Els R. Nieuwenhuijsen

1 November 2015 in Annals of Epidemiology
Verified
Journal Article
Closed access
PCPhilippa Clarke
Philippa Clarke
JWJennifer Weuve
Jennifer Weuve
LBLisa Barnes
Lisa Barnes
DEDenis A. Evans
Denis A. Evans
CLCarlos F. Mendes de Leon
Carlos F. Mendes de Leon

1 November 2019 in Health & Place
Verified
Journal Article
Closed access
JFJessica Finlay
Jessica Finlay
MEMichael Esposito
Michael Esposito
MKMin Hee Kim
Min Hee Kim
IGIris Gomez-Lopez
Iris Gomez-Lopez
PCPhilippa Clarke
Philippa Clarke