In recent years, translational plasma medicine (TPM), as a novel application area of plasmas, has attracted much attention of experts from both academic and clinical fields. State‐of‐the‐art of the lab‐scale research and clinical trials of the cold atmospheric plasmas (CAPs) in the stomatology are reviewed in detail from the direct and indirect applications of the CAPs. Based on the discussions concerning the relationship between the plasma stomatology and the plasma medicine, it is indicated that it would be an important reference for promoting the TPM starting from the fundamental and application studies in the field of dentistry, which is also one of the most three promising application fields of plasma medicine.

To evaluate whether atmospheric-pressure dielectric-barrier-discharge plasma treatment of zirconia enhances its biocompatibility with human gingival fibroblasts. The zirconia disks were divided into four groups and treated using helium atmospheric-pressure dielectric-barrier-discharge plasmas for 30, 60 or 90 s or left untreated. The surface morphology, wettability and chemical elements were analyzed. Fibroblasts density, morphology, morphometry and attachment-related genes expression were measured at different time points from 3 to 72 h. After plasma treatment, the surface morphology and roughness remained the same, while the contact angle decreased from 78.31° to 43.71°, and the surface C/O ratio decreased from 3.17 to 0.89. The surficial areas and perimeters of HGFs were increased two-fold in the treated groups at 3 h. Fibroblasts density increased on treated disks at all time points, especially the ones treated for 60 s. Attachment-related genes in the groups treated for 30 and 60 s were significantly higher at 3 and 24 h. The helium atmospheric-pressure dielectric-barrier-discharge plasma treatment enhances the biological behavior of fibroblasts on zirconia by increasing the expression of attachment-related genes within 24 h and promoting the cell density during longer culture times. Wettability of zirconia, an important physicochemical property, has a vital influence on the cell behaviors.

Background: A complete denture (CD) can be duplicated with a conventional or digital protocol. However, there are no comparative studies of these methods. This study aimed to compare the trueness and efficiency of conventional and digital CD duplication methods. Methods: A mandibular CD was digitized as the virtual reference model and duplicated using five methods (n = 10). The trueness (root mean square (RMS)) was calculated for the whole denture and across the dentition, cameo denture extension, and intaglio portions. The manual labor time spent during denture duplication was also recorded at different steps. The trueness and labor time comparisons were statistically analyzed among the five groups (α = 0.05). Results: The conventional group was the least true with the largest RMS (mean, 95% CI) in all of the comparisons. The four digital groups yielded similar trueness values across the dentition, cameo denture extension, and intaglio areas, yet they had a significant difference in the whole denture comparison between the Digital-CBCT-SLA printer (0.17, 0.15–0.19 mm) and Digital-Laboratory Scanner-SLA printer (0.13, 0.11–0.15 mm). The conventional protocol required longer trimming and finishing time (7.55 ± 1.02 min), as well as total labor time (27.64 ± 1.72 min) than the other four digital techniques. Conclusions: The conventional CD duplication method was less true and efficient than digital techniques.