Ashok kumar

Prof. Ashok kumar

CSBB, Panjab University, Chandigarh, India
orcid

Research Focus & Metrics

Academic Career Length

21Years (2006-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 January 2016 in Biological Procedures Online
Verified
Journal Article
Open access
PDF file
Ashok Kumar NaddaAshok Kumar Nadda
Ashok Kumar Nadda
KDKartik Dhar
Kartik Dhar
SKShamsher Singh Kanwar
Shamsher Singh Kanwar
PAPankaj Kumar Arora
Pankaj Kumar Arora
Lipases are industrial biocatalysts, which are involved in several novel reactions, occurring in aqueous medium as well as non-aqueous medium. Furthermore, they are well-known for their remarkable ability to carry out a wide variety of chemo-, regio- and enantio-selective transformations. Lipases have been gained attention worldwide by organic chemists due to their general ease of handling, broad substrate tolerance, high stability towards temperatures and solvents and convenient commercial availability. Most of the synthetic reactions on industrial scale are carried out in organic solvents because of the easy solubility of non-polar compounds. The effect of organic system on their stability and activity may determine the biocatalysis pace. Because of worldwide use of lipases, there is a need to understand the mechanisms behind the lipase-catalyzed reactions in organic solvents. The unique interfacial activation of lipases has always fascinated enzymologists and recently, biophysicists and crystallographers have made progress in understanding the structure-function relationships of these enzymes. The present review describes the advantages of lipase-catalyzed reactions in organic solvents and various effects of organic solvents on their activity.

8 November 2016 in Frontiers in Plant Science
Verified
Journal Article
Open access
PDF file
SSSukhdev Singh
Sukhdev Singh
BSBhupender Sharma
Bhupender Sharma
SKShamsher S. Kanwar
Shamsher S. Kanwar
Ashok Kumar NaddaAshok Kumar Nadda
Ashok Kumar Nadda
Cancer is a serious concern at present. A large number of patients die each year due to cancer illnesses in spite of several interventions available. Development of an effective and side effects lacking anticancer therapy is the trending research direction in healthcare pharmacy. Chemical entities present in plants proved to be very potential in this regard. Bioactive phytochemicals are preferential as they pretend differentially on cancer cells only, without altering normal cells. Carcinogenesis is a complex process and includes multiple signaling events. Phytochemicals are pleiotropic in their function and target these events in multiple manners; hence they are most suitable candidate for anticancer drug development. Efforts are in progress to develop lead candidates from phytochemicals those can block or retard the growth of cancer without any side effect. Several phytochemicals manifest anticancer function in vitro and in vivo. This article deals with these lead phytomolecules with their action mechanisms on nuclear and cellular factors involved in carcinogenesis. Additionally, druggability parameters and clinical development of anticancer phytomolecules have also been discussed.

1 November 2021 in Environmental Research
Verified
Journal Article
Closed access
VSVatika Soni
Vatika Soni
Pankaj RaizadaPankaj Raizada
Pankaj Raizada
PSPardeep Singh
Pardeep Singh
HCHoang Ngoc Cuong
Hoang Ngoc Cuong
RSRangabhashiyam S
Rangabhashiyam S
VNVan-Huy Nguyen
Van-Huy Nguyen

1 March 2019 in Chemical Engineering Journal
Verified
Journal Article
Closed access
Ashok Kumar NaddaAshok Kumar Nadda
Ashok Kumar Nadda
GPGi Dae Park
Gi Dae Park
SANJAY KUMAR SINGH PATELSANJAY KUMAR SINGH PATEL
SANJAY KUMAR SINGH PATEL
SKSanath Kondaveeti
Sanath Kondaveeti
SOSachin Otari
Sachin Otari
JLJung-Kul Lee
Jung-Kul Lee

1 February 2020 in Journal of Cleaner Production
Verified
Journal Article
Closed access
TSTanvi Sharma
Tanvi Sharma
SSSwati Sharma
Swati Sharma
HKHesam Kamyab
Hesam Kamyab
Ashok Kumar NaddaAshok Kumar Nadda
Ashok Kumar Nadda

14 February 2018 in Clean Technologies and Environmental Policy
Verified
Journal Article
Closed access
PDF file
SSSWATI SHARMA
SWATI SHARMA
AGArun Gupta
Arun Gupta
Ashok Kumar NaddaAshok Kumar Nadda
Ashok Kumar Nadda
CKChua Gek Kee
Chua Gek Kee
Hesam KamyabHesam Kamyab
Hesam Kamyab
SSSyed Mohd Saufi
Syed Mohd Saufi