Jose Manuel Lorenzo

Dr. Jose Manuel Lorenzo

Centro Tecnológico de la Carne
orcid

Research Focus & Metrics

Academic Career Length

36Years (1991-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 September 2019 in Antioxidants
Verified
Journal Article
Open access
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Ruben Domínguez-ValenciaRuben Domínguez-Valencia
Ruben Domínguez-Valencia
Mirian PateiroMirian Pateiro
Mirian Pateiro
Mohammed GagaouaMohammed Gagaoua
Mohammed Gagaoua
Francisco J. BarbaFrancisco J. Barba
Francisco J. Barba
WZWangang Zhang
Wangang Zhang
Jose Manuel LorenzoJose Manuel Lorenzo
Jose Manuel Lorenzo
Meat and meat products are a fundamental part of the human diet. The protein and vitamin content, as well as essential fatty acids, gives them an appropriate composition to complete the nutritional requirements. However, meat constituents are susceptible to degradation processes. Among them, the most important, after microbial deterioration, are oxidative processes, which affect lipids, pigments, proteins and vitamins. During these reactions a sensory degradation of the product occurs, causing consumer rejection. In addition, there is a nutritional loss that leads to the formation of toxic substances, so the control of oxidative processes is of vital importance for the meat industry. Nonetheless, despite lipid oxidation being widely investigated for decades, the complex reactions involved in the process, as well as the different pathways and factors that influenced them, make that lipid oxidation mechanisms have not yet been completely understood. Thus, this article reviews the fundamental mechanisms of lipid oxidation, the most important oxidative reactions, the main factors that influence lipid oxidation, and the routine methods to measure compounds derived from lipid oxidation in meat.

25 March 2020 in Annual Review of Food Science and Technology
Verified
Journal Article
Closed access
DGDaniel Granato
Daniel Granato
Francisco J. BarbaFrancisco J. Barba
Francisco J. Barba
Danijela Bursać KovačevićDanijela Bursać Kovačević
Danijela Bursać Kovačević
Jose Manuel LorenzoJose Manuel Lorenzo
Jose Manuel Lorenzo
ACAdriano G. Cruz
Adriano G. Cruz
Predrag PutnikPredrag Putnik
Predrag Putnik
Functional foods is a very popular term in the social and scientific media; consequently, food producers have invested resources in the development of processed foods that may provide added functional benefits to consumers’ well-being. Because of intrinsic regulation and end-of-use purposes in different countries, worldwide meanings and definitions of this term are still unclear. Hence, here we standardize this definition and propose a guideline to attest that some ingredients or foods truly deserve this special designation. Furthermore, focus is directed at the most recent studies and practical guidelines that can be used to develop and test the efficacy of potentially functional foods and ingredients. The most widespread functional ingredients, such as polyunsaturated fatty acids (PUFAs), probiotics/prebiotics/synbiotics, and antioxidants, and their technological means of delivery in food products are described. The review discusses the steps that food companies should take to ensure that their developed food product is truly functional.

2 April 2020 in Green Chemistry
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Journal Article
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Farid ChematFarid Chemat
Farid Chemat
Maryline VianMaryline Vian
Maryline Vian
AFAnne-Sylvie Fabiano-Tixier
Anne-Sylvie Fabiano-Tixier
MNMarinela Nutrizio
Marinela Nutrizio
Anet Režek JambrakAnet Režek Jambrak
Anet Režek Jambrak
Giancarlo CravottoGiancarlo Cravotto
Giancarlo Cravotto
This review presents innovative extraction techniques and their role in promoting sustainable ingredients for the food, cosmetic and pharmaceutical industries.

11 March 2021 in Molecules
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Journal Article
Open access
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Mirian PateiroMirian Pateiro
Mirian Pateiro
BGBelén Gómez
Belén Gómez
PMPaulo Munekata
Paulo Munekata
Francisco J. BarbaFrancisco J. Barba
Francisco J. Barba
Predrag PutnikPredrag Putnik
Predrag Putnik
Jose Manuel LorenzoJose Manuel Lorenzo
Jose Manuel Lorenzo
The design of functional foods has grown recently as an answer to rising consumers’ concerns and demands for natural, nutritional and healthy food products. Nanoencapsulation is a technique based on enclosing a bioactive compound (BAC) in liquid, solid or gaseous states within a matrix or inert material for preserving the coated substance (food or flavor molecules/ingredients). Nanoencapsulation can improve stability of BACs, improving the regulation of their release at physiologically active sites. Regarding materials for food and nutraceutical applications, the most used are carbohydrate-, protein- or lipid-based alternatives such as chitosan, peptide–chitosan and β-lactoglobulin nanoparticles (NPs) or emulsion biopolymer complexes. On the other hand, the main BACs used in foods for health promoting, including antioxidants, antimicrobials, vitamins, probiotics and prebiotics and others (minerals, enzymes and flavoring compounds). Nanotechnology can also play notable role in the development of programmable food, an original futuristic concept promising the consumers to obtain high quality food of desired nutritive and sensory characteristics.

12 September 2021 in Cancers
Verified
Journal Article
Open access
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SASumaira Anjum
Sumaira Anjum
MHMariam Hashim
Mariam Hashim
SMSara Asad Malik
Sara Asad Malik
MKMaha Khan
Maha Khan
Jose Manuel LorenzoJose Manuel Lorenzo
Jose Manuel Lorenzo
Christophe HanoChristophe Hano
Christophe Hano
Cancer is regarded as one of the most deadly and mirthless diseases and it develops due to the uncontrolled proliferation of cells. To date, varieties of traditional medications and chemotherapies have been utilized to fight tumors. However, their immense drawbacks, such as reduced bioavailability, insufficient supply, and significant adverse effects, make their use limited. Nanotechnology has evolved rapidly in recent years and offers a wide spectrum of applications in the healthcare sectors. Nanoscale materials offer strong potential for curing cancer as they pose low risk and fewer complications. Several metal oxide NPs are being developed to diagnose or treat malignancies, but zinc oxide nanoparticles (ZnO NPs) have remarkably demonstrated their potential in the diagnosis and treatment of various types of cancers due to their biocompatibility, biodegradability, and unique physico-chemical attributes. ZnO NPs showed cancer cell specific toxicity via generation of reactive oxygen species and destruction of mitochondrial membrane potential, which leads to the activation of caspase cascades followed by apoptosis of cancerous cells. ZnO NPs have also been used as an effective carrier for targeted and sustained delivery of various plant bioactive and chemotherapeutic anticancerous drugs into tumor cells. In this review, at first we have discussed the role of ZnO NPs in diagnosis and bio-imaging of cancer cells. Secondly, we have extensively reviewed the capability of ZnO NPs as carriers of anticancerous drugs for targeted drug delivery into tumor cells, with a special focus on surface functionalization, drug-loading mechanism, and stimuli-responsive controlled release of drugs. Finally, we have critically discussed the anticancerous activity of ZnO NPs on different types of cancers along with their mode of actions. Furthermore, this review also highlights the limitations and future prospects of ZnO NPs in cancer theranostic.

28 July 2020 in Foods
Verified
Journal Article
Open access
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Cecilia Jiménez-LópezCecilia Jiménez-López
Cecilia Jiménez-López
Maria CarpenaMaria Carpena
Maria Carpena
Catarina Lourenço-LopesCatarina Lourenço-Lopes
Catarina Lourenço-Lopes
MGMaria Gallardo-Gomez
Maria Gallardo-Gomez
Jose Manuel LorenzoJose Manuel Lorenzo
Jose Manuel Lorenzo
Jesus Simal-GandaraJesus Simal-Gandara
Jesus Simal-Gandara
(1) Background: Extra virgin olive oil (EVOO) is responsible for a large part of many health benefits associated to Mediterranean diet as it is a fundamental ingredient of this diet. The peculiarities of this golden, highly valued product are in part due to the requirements that must be met to achieve this title, namely, it has to be obtained using exclusively mechanical procedures, its free acidity cannot be greater than 0.8%, it must not show sensory defects, and it has to possess a fruity taste. (2) Methods: All these characteristics are key factors to EVOO quality, thus the chemical composition of these many health-promoting compounds, such as unsaturated fatty acids (which are also the major compounds, especially oleic acid), as well as minor components such as tocopherols or phenolic compounds (which behave as natural antioxidants) must be preserved. (3) Results: Due to the presence of all these compounds, the daily consumption of EVOO entails health benefits such as cardioprotective, antioxidant, anti-inflammatory, anti-tumor properties or acting as regulator of the intestinal microbiota, among others. (4) Conclusions: Taking all together, conserving EVOO chemical composition is essential to preserve its properties, so it is worth to control certain factors during storage like exposure to light, temperature, oxygen presence or the chosen packaging material, to maintain its quality and extend its shelf-life until its consumption.