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Sumaira Anjum
Department of Biotechnology, Kinnaird College for Women, Jail Road, Lahore 54000, Pakistan

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Review
Published: 26 July 2021 in Plants
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Plant secondary metabolites are known to have a variety of biological activities beneficial to human health. They are becoming more popular as a result of their unique features and account for a major portion of the pharmacological industry. However, obtaining secondary metabolites directly from wild plants has substantial drawbacks, such as taking a long time, posing a risk of species extinction owing to over-exploitation, and producing a limited quantity. Thus, there is a paradigm shift towards the employment of plant tissue culture techniques for the production of key secondary metabolites in vitro. Elicitation appears to be a viable method for increasing phytochemical content and improving the quality of medicinal plants and fruits and vegetables. In vitro culture elicitation activates the plant’s defense response and increases the synthesis of secondary metabolites in larger proportions, which are helpful for therapeutic purposes. In this respect, light has emerged as a unique and efficient elicitor for enhancing the in vitro production of pharmacologically important secondary metabolites. Various types of light (UV, fluorescent, and LEDs) have been found as elicitors of secondary metabolites, which are described in this review.

ACS Style

Mariam Hashim; Bushra Ahmad; Samantha Drouet; Christophe Hano; Bilal Abbasi; Sumaira Anjum. Comparative Effects of Different Light Sources on the Production of Key Secondary Metabolites in Plants In Vitro Cultures. Plants 2021, 10, 1521 .

AMA Style

Mariam Hashim, Bushra Ahmad, Samantha Drouet, Christophe Hano, Bilal Abbasi, Sumaira Anjum. Comparative Effects of Different Light Sources on the Production of Key Secondary Metabolites in Plants In Vitro Cultures. Plants. 2021; 10 (8):1521.

Chicago/Turabian Style

Mariam Hashim; Bushra Ahmad; Samantha Drouet; Christophe Hano; Bilal Abbasi; Sumaira Anjum. 2021. "Comparative Effects of Different Light Sources on the Production of Key Secondary Metabolites in Plants In Vitro Cultures." Plants 10, no. 8: 1521.

Review
Published: 21 July 2021 in Pharmaceuticals
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Healthcare, as a basic human right, has often become the focus of the development of innovative technologies. Technological progress has significantly contributed to the provision of high-quality, on-time, acceptable, and affordable healthcare. Advancements in nanoscience have led to the emergence of a new generation of nanostructures. Each of them has a unique set of properties that account for their astonishing applications. Since its inception, nanotechnology has continuously affected healthcare and has exerted a tremendous influence on its transformation, contributing to better outcomes. In the last two decades, the world has seen nanotechnology taking steps towards its omnipresence and the process has been accelerated by extensive research in various healthcare sectors. The inclusion of nanotechnology and its allied nanocarriers/nanosystems in medicine is known as nanomedicine, a field that has brought about numerous benefits in disease prevention, diagnosis, and treatment. Various nanosystems have been found to be better candidates for theranostic purposes, in contrast to conventional ones. This review paper will shed light on medically significant nanosystems, as well as their applications and limitations in areas such as gene therapy, targeted drug delivery, and in the treatment of cancer and various genetic diseases. Although nanotechnology holds immense potential, it is yet to be exploited. More efforts need to be directed to overcome these limitations and make full use of its potential in order to revolutionize the healthcare sector in near future.

ACS Style

Sumaira Anjum; Sara Ishaque; Hijab Fatima; Wajiha Farooq; Christophe Hano; Bilal Abbasi; Iram Anjum. Emerging Applications of Nanotechnology in Healthcare Systems: Grand Challenges and Perspectives. Pharmaceuticals 2021, 14, 707 .

AMA Style

Sumaira Anjum, Sara Ishaque, Hijab Fatima, Wajiha Farooq, Christophe Hano, Bilal Abbasi, Iram Anjum. Emerging Applications of Nanotechnology in Healthcare Systems: Grand Challenges and Perspectives. Pharmaceuticals. 2021; 14 (8):707.

Chicago/Turabian Style

Sumaira Anjum; Sara Ishaque; Hijab Fatima; Wajiha Farooq; Christophe Hano; Bilal Abbasi; Iram Anjum. 2021. "Emerging Applications of Nanotechnology in Healthcare Systems: Grand Challenges and Perspectives." Pharmaceuticals 14, no. 8: 707.

Review
Published: 14 February 2021 in Applied Sciences
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Flavonoids represent a popular class of industrially important bioactive compounds. They possess valuable health-benefiting and disease preventing properties, and therefore they are an important component of the pharmaceutical, nutraceutical, cosmetical and medicinal industries. Moreover, flavonoids possess significant antiallergic, antihepatotoxic, anti-inflammatory, antioxidant, antitumor, antiviral, and antibacterial as well as cardio-protective activities. Due to these properties, there is a rise in global demand for flavonoids, forming a significant part of the world market. However, obtaining flavonoids directly from plants has some limitations, such as low quantity, poor extraction, over-exploitation, time consuming process and loss of flora. Henceforth, there is a shift towards the in vitro production of flavonoids using the plant tissue culture technique to achieve better yields in less time. In order to achieve the productivity of flavonoids at an industrially competitive level, elicitation is a useful tool. The elicitation of in vitro cultures induces stressful conditions to plants, activates the plant defense system and enhances the accumulation of secondary metabolites in higher quantities. In this regard, nanoparticles (NPs) have emerged as novel and effective elicitors for enhancing the in vitro production of industrially important flavonoids. Different classes of NPs, including metallic NPs (silver and copper), metallic oxide NPs (copper oxide, iron oxide, zinc oxide, silicon dioxide) and carbon nanotubes, are widely reported as nano-elicitors of flavonoids discussed herein. Lastly, the mechanisms of NPs as well as knowledge gaps in the area of the nano-elicitation of flavonoids have been highlighted in this review.

ACS Style

Amna Khan; Sidra Kousar; Duangjai Tungmunnithum; Christophe Hano; Bilal Abbasi; Sumaira Anjum. Nano-Elicitation as an Effective and Emerging Strategy for in Vitro Production of Industrially Important Flavonoids. Applied Sciences 2021, 11, 1694 .

AMA Style

Amna Khan, Sidra Kousar, Duangjai Tungmunnithum, Christophe Hano, Bilal Abbasi, Sumaira Anjum. Nano-Elicitation as an Effective and Emerging Strategy for in Vitro Production of Industrially Important Flavonoids. Applied Sciences. 2021; 11 (4):1694.

Chicago/Turabian Style

Amna Khan; Sidra Kousar; Duangjai Tungmunnithum; Christophe Hano; Bilal Abbasi; Sumaira Anjum. 2021. "Nano-Elicitation as an Effective and Emerging Strategy for in Vitro Production of Industrially Important Flavonoids." Applied Sciences 11, no. 4: 1694.

Research article
Published: 01 January 2021 in Artificial Cells, Nanomedicine, and Biotechnology
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Zinc oxide nanoparticles (ZnO-NPs) have been produced by physical and chemical methods. Here, the comparative evaluation of both chemically-synthesised ZnO-NPs (C-ZNPs) and in-vitro cultured S. marianum mediated green-synthesised ZnO-NPs (G-ZNPs) were investigated on seed germination frequency, root and shoot growth, callus induction and biochemical profile of medicinally important plant Silybum marianum. Of all the treatments, callus-mediated ZnO-NPs gave optimum results for seed germination (65%), plantlet’s root length (4.3 cm), shoot length (5.3 cm) and fresh and dry weights (220.4 g L−1 and 21.23 g L−1, respectively). Similarly, the accumulation of phenolic (12.3 µg/mg DW) and flavonoid (2.8 µg/mg DW) contents were also enhanced in callus cultures treated with G-ZNPs. We also observed maximum antioxidant activity (99%) in callus cultures treated with G-ZNPs, however, in case of plantlets, these activities were found highest for in-vitro whole plant-mediated ZnO-NPs. Moreover, G-ZNPs also enhanced total protein content (265.32 BSAE/20g FW) in callus cultures. G-ZNPs were further assessed for their effects on several multidrug resistant bacterial strains and human liver carcinoma (HepG2) cells and our findings revealed that callus extracts treated with G-ZNPs show ameliorated antibacterial (highest zone of inhibition (19 mm) against Klebsiella pneumonia) and anticancer (highest cytotoxicity of 64%) activities.

ACS Style

Faryal Saeed; Muhammad Younas; Hina Fazal; Sadaf Mushtaq; Faiz Ur Rahman; Muzamil Shah; Sumaira Anjum; Nisar Ahmad; Mohammad Ali; Christophe Hano; Bilal Haider Abbasi. Green and chemically synthesized zinc oxide nanoparticles: effects on in-vitro seedlings and callus cultures of Silybum marianum and evaluation of their antimicrobial and anticancer potential. Artificial Cells, Nanomedicine, and Biotechnology 2021, 49, 450 -460.

AMA Style

Faryal Saeed, Muhammad Younas, Hina Fazal, Sadaf Mushtaq, Faiz Ur Rahman, Muzamil Shah, Sumaira Anjum, Nisar Ahmad, Mohammad Ali, Christophe Hano, Bilal Haider Abbasi. Green and chemically synthesized zinc oxide nanoparticles: effects on in-vitro seedlings and callus cultures of Silybum marianum and evaluation of their antimicrobial and anticancer potential. Artificial Cells, Nanomedicine, and Biotechnology. 2021; 49 (1):450-460.

Chicago/Turabian Style

Faryal Saeed; Muhammad Younas; Hina Fazal; Sadaf Mushtaq; Faiz Ur Rahman; Muzamil Shah; Sumaira Anjum; Nisar Ahmad; Mohammad Ali; Christophe Hano; Bilal Haider Abbasi. 2021. "Green and chemically synthesized zinc oxide nanoparticles: effects on in-vitro seedlings and callus cultures of Silybum marianum and evaluation of their antimicrobial and anticancer potential." Artificial Cells, Nanomedicine, and Biotechnology 49, no. 1: 450-460.

Review
Published: 30 December 2020 in Sustainability
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Melatonin, a multifunctional signaling molecule, is ubiquitously distributed in different parts of a plant and responsible for stimulating several physiochemical responses against adverse environmental conditions in various plant systems. Melatonin acts as an indoleamine neurotransmitter and is primarily considered as an antioxidant agent that can control reactive oxygen and nitrogen species in plants. Melatonin, being a signaling agent, induces several specific physiological responses in plants that might serve to enhance photosynthesis, growth, carbon fixation, rooting, seed germination and defense against several biotic and abiotic stressors. It also works as an important modulator of gene expression related to plant hormones such as in the metabolism of indole-3-acetic acid, cytokinin, ethylene, gibberellin and auxin carrier proteins. Additionally, the regulation of stress-specific genes and the activation of pathogenesis-related protein and antioxidant enzyme genes under stress conditions make it a more versatile molecule. Because of the diversity of action of melatonin, its role in plant growth, development, behavior and regulation of gene expression it is a plant’s master regulator. This review outlines the main functions of melatonin in the physiology, growth, development and regulation of higher plants. Its role as anti-stressor agent against various abiotic stressors, such as drought, salinity, temperatures, UV radiation and toxic chemicals, is also analyzed critically. Additionally, we have also identified many new aspects where melatonin may have possible roles in plants, for example, its function in improving the storage life and quality of fruits and vegetables, which can be useful in enhancing the environmentally friendly crop production and ensuring food safety.

ACS Style

Khadija Nawaz; Rimsha Chaudhary; Ayesha Sarwar; Bushra Ahmad; Asma Gul; Christophe Hano; Bilal Abbasi; Sumaira Anjum. Melatonin as Master Regulator in Plant Growth, Development and Stress Alleviator for Sustainable Agricultural Production: Current Status and Future Perspectives. Sustainability 2020, 13, 294 .

AMA Style

Khadija Nawaz, Rimsha Chaudhary, Ayesha Sarwar, Bushra Ahmad, Asma Gul, Christophe Hano, Bilal Abbasi, Sumaira Anjum. Melatonin as Master Regulator in Plant Growth, Development and Stress Alleviator for Sustainable Agricultural Production: Current Status and Future Perspectives. Sustainability. 2020; 13 (1):294.

Chicago/Turabian Style

Khadija Nawaz; Rimsha Chaudhary; Ayesha Sarwar; Bushra Ahmad; Asma Gul; Christophe Hano; Bilal Abbasi; Sumaira Anjum. 2020. "Melatonin as Master Regulator in Plant Growth, Development and Stress Alleviator for Sustainable Agricultural Production: Current Status and Future Perspectives." Sustainability 13, no. 1: 294.

Review
Published: 06 November 2020 in Biomolecules
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With the increase in biotechnological, environmental, and nutraceutical importance of algae, about 100 whole genomic sequences of algae have been published, and this figure is expected to double in the coming years. The phenotypic and ecological diversity among algae hints at the range of functional capabilities encoded by algal genomes. In order to explore the biodiversity of algae and fully exploit their commercial potential, understanding their evolutionary, structural, functional, and developmental aspects at genomic level is a pre-requisite. So forth, the algal genomic analysis revealed us that algae evolved through endosymbiotic gene transfer, giving rise to around eight phyla. Amongst the diverse algal species, the unicellular green algae Chlamydomonas reinhardtii has attained the status of model organism as it is an ideal organism to elucidate the biological processes critical to plants and animals, as well as commercialized to produce range of bio-products. For this review, an overview of evolutionary process of algae through endosymbiosis in the light of genomics, as well as the phylogenomic, studies supporting the evolutionary process of algae was reviewed. Algal genomics not only helped us to understand the evolutionary history of algae but also may have an impact on our future by helping to create algae-based products and future biotechnological approaches.

ACS Style

Amna Komal Khan; Humera Kausar; Syyada Samra Jaferi; Samantha Drouet; Christophe Hano; Bilal Haider Abbasi; Sumaira Anjum. An Insight into the Algal Evolution and Genomics. Biomolecules 2020, 10, 1524 .

AMA Style

Amna Komal Khan, Humera Kausar, Syyada Samra Jaferi, Samantha Drouet, Christophe Hano, Bilal Haider Abbasi, Sumaira Anjum. An Insight into the Algal Evolution and Genomics. Biomolecules. 2020; 10 (11):1524.

Chicago/Turabian Style

Amna Komal Khan; Humera Kausar; Syyada Samra Jaferi; Samantha Drouet; Christophe Hano; Bilal Haider Abbasi; Sumaira Anjum. 2020. "An Insight into the Algal Evolution and Genomics." Biomolecules 10, no. 11: 1524.

Review
Published: 30 October 2020 in Biomolecules
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Algae have long been exploited commercially and industrially as food, feed, additives, cosmetics, pharmaceuticals, and fertilizer, but now the trend is shifting towards the algae-mediated green synthesis of nanoparticles (NPs). This trend is increasing day by day, as algae are a rich source of secondary metabolites, easy to cultivate, have fast growth, and are scalable. In recent era, green synthesis of NPs has gained widespread attention as a safe, simple, sustainable, cost-effective, and eco-friendly protocol. The secondary metabolites from algae reduce, cap, and stabilize the metal precursors to form metal, metal oxide, or bimetallic NPs. The NPs synthesis could either be intracellular or extracellular depending on the location of NPs synthesis and reducing agents. Among the diverse range of algae, the most widely investigated algae for the biosynthesis of NPs documented are brown, red, blue-green, micro and macro green algae. Due to the biocompatibility, safety and unique physico-chemical properties of NPs, the algal biosynthesized NPs have also been studied for their biomedical applications, which include anti-bacterial, anti-fungal, anti-cancerous, anti-fouling, bioremediation, and biosensing activities. In this review, the rationale behind the algal-mediated biosynthesis of metallic, metallic oxide, and bimetallic NPs from various algae have been reviewed. Furthermore, an insight into the mechanism of biosynthesis of NPs from algae and their biomedical applications has been reviewed critically.

ACS Style

Rimsha Chaudhary; Khadija Nawaz; Amna Komal Khan; Christophe Hano; Bilal Haider Abbasi; Sumaira Anjum. An Overview of the Algae-Mediated Biosynthesis of Nanoparticles and Their Biomedical Applications. Biomolecules 2020, 10, 1498 .

AMA Style

Rimsha Chaudhary, Khadija Nawaz, Amna Komal Khan, Christophe Hano, Bilal Haider Abbasi, Sumaira Anjum. An Overview of the Algae-Mediated Biosynthesis of Nanoparticles and Their Biomedical Applications. Biomolecules. 2020; 10 (11):1498.

Chicago/Turabian Style

Rimsha Chaudhary; Khadija Nawaz; Amna Komal Khan; Christophe Hano; Bilal Haider Abbasi; Sumaira Anjum. 2020. "An Overview of the Algae-Mediated Biosynthesis of Nanoparticles and Their Biomedical Applications." Biomolecules 10, no. 11: 1498.

Journal article
Published: 17 June 2020 in Biomolecules
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Linum usitatissimum biosynthesizes lignans and neolignans that are diet and medicinally valuable metabolites. In recent years, zinc oxide nanoparticles (ZnONPs) have emerged as potential elicitors for the enhanced biosynthesis of commercial secondary metabolites. Herein, we investigated the influence of biogenic ZnONPs on both seedlings and stem-derived callus of L. usitatissimum. Seedlings of L. usitatissimum grown on Murashige and Skoog (MS) medium supplemented with ZnONPs (1–1000 mg/L) presented the highest antioxidant activity, total phenolic content, total flavonoid content, peroxidase and superoxide dismutase activities at 500 mg/L, while the maximum plantlet length was achieved with 10 mg/L. Likewise, the high-performance liquid chromatography (HPLC) analysis revealed the enhanced production of secoisolariciresinol diglucoside, lariciresinol diglucoside, dehydrodiconiferyl alcohol glucoside and guaiacylglycerol-β-coniferyl alcohol ether glucoside in the plantlets grown on the 500 mg/L ZnONPs. On the other hand, the stem explants were cultured on MS media comprising 1-naphthaleneacetic acid (1 mg/L) and ZnONPs (1–50 mg/L). The highest antioxidant and other activities with an enhanced rooting effect were noted in 25 mg/L ZnONP-treated callus. Similarly, the maximum metabolites were also accumulated in 25 mg/L ZnONP-treated callus. In both systems, the dose-dependent production of reactive oxygen species (ROS) was recorded, resulting in oxidative damage with a more pronounced toxic effect on in vitro cultures. Altogether, the results from this study constitute a first comprehensive view of the impact of ZnONPs on the oxidative stress and antioxidant responses in seedlings vs. in vitro cultures.

ACS Style

Afifa Zaeem; Samantha Drouet; Sumaira Anjum; Razia Khurshid; Muhammad Younas; Jean Philippe Blondeau; Duangjai Tungmunnithum; Nathalie Giglioli-Guivarc’H; Christophe Hano; Bilal Haider Abbasi. Effects of Biogenic Zinc Oxide Nanoparticles on Growth and Oxidative Stress Response in Flax Seedlings vs. In Vitro Cultures: A Comparative Analysis. Biomolecules 2020, 10, 918 .

AMA Style

Afifa Zaeem, Samantha Drouet, Sumaira Anjum, Razia Khurshid, Muhammad Younas, Jean Philippe Blondeau, Duangjai Tungmunnithum, Nathalie Giglioli-Guivarc’H, Christophe Hano, Bilal Haider Abbasi. Effects of Biogenic Zinc Oxide Nanoparticles on Growth and Oxidative Stress Response in Flax Seedlings vs. In Vitro Cultures: A Comparative Analysis. Biomolecules. 2020; 10 (6):918.

Chicago/Turabian Style

Afifa Zaeem; Samantha Drouet; Sumaira Anjum; Razia Khurshid; Muhammad Younas; Jean Philippe Blondeau; Duangjai Tungmunnithum; Nathalie Giglioli-Guivarc’H; Christophe Hano; Bilal Haider Abbasi. 2020. "Effects of Biogenic Zinc Oxide Nanoparticles on Growth and Oxidative Stress Response in Flax Seedlings vs. In Vitro Cultures: A Comparative Analysis." Biomolecules 10, no. 6: 918.

Journal article
Published: 08 May 2020 in Molecules
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Solanum xanthocarpum is considered an important traditional medicinal herb because of its unique antioxidant, and anti-diabetic, anti-aging, and anti-inflammatory potential. Because of the over exploitation linked to its medicinal properties as well as destruction of its natural habitat, S. xanthocarpum is now becoming endangered and its supply is limited. Plant in vitro culture and elicitation are attractive alternative strategies to produce biomass and stimulate biosynthesis of medicinally important phytochemicals. Here, we investigated the potential influence of seven different monochromatic light treatments on biomass and secondary metabolites accumulation in callus culture of S. xanthocarpum as well as associated biological activities of the corresponding extracts. Among different light treatments, highest biomass accumulation was observed in white light-treated callus culture. Optimum accumulation of total flavonoid contents (TFC) and total phenolic contents (TPC) were observed in callus culture kept under continuous white and blue light respectively than control. Quantification of phytochemicals through HPLC revealed that optimum production of caffeic acid (0.57 ± 0.06 mg/g DW), methyl-caffeate (17.19 mg/g ± 1.79 DW), scopoletin (2.28 ± 0.13 mg/g DW), and esculetin (0.68 ± 0.07 mg/g DW) was observed under blue light callus cultures. Compared to the classic photoperiod condition, caffeic acid, methyl-caffeate, scopoletin, and esculetin were accumulated 1.7, 2.5, 1.1, and 1.09-folds higher, respectively. Moreover, high in vitro cell free antioxidant, anti-diabetic, anti-aging, and anti-inflammatory activities were closely associated with the production of these secondary metabolites. These results clearly showed the interest to apply multispectral light as elicitor of in vitro callus cultures S. xanthocarpum to promote the production of important phytochemicals, and allow us to propose this system as an alternative for the collection of this endangered species from the wild.

ACS Style

Hazrat Usman; Muhammad Asad Ullah; Hasnain Jan; Aisha Siddiquah; Samantha Drouet; Sumaira Anjum; Nathalie Giglioli-Guviarc’H; Christophe Hano; Bilal Haider Abbasi. Interactive Effects of Wide-Spectrum Monochromatic Lights on Phytochemical Production, Antioxidant and Biological Activities of Solanum xanthocarpum Callus Cultures. Molecules 2020, 25, 2201 .

AMA Style

Hazrat Usman, Muhammad Asad Ullah, Hasnain Jan, Aisha Siddiquah, Samantha Drouet, Sumaira Anjum, Nathalie Giglioli-Guviarc’H, Christophe Hano, Bilal Haider Abbasi. Interactive Effects of Wide-Spectrum Monochromatic Lights on Phytochemical Production, Antioxidant and Biological Activities of Solanum xanthocarpum Callus Cultures. Molecules. 2020; 25 (9):2201.

Chicago/Turabian Style

Hazrat Usman; Muhammad Asad Ullah; Hasnain Jan; Aisha Siddiquah; Samantha Drouet; Sumaira Anjum; Nathalie Giglioli-Guviarc’H; Christophe Hano; Bilal Haider Abbasi. 2020. "Interactive Effects of Wide-Spectrum Monochromatic Lights on Phytochemical Production, Antioxidant and Biological Activities of Solanum xanthocarpum Callus Cultures." Molecules 25, no. 9: 2201.

Journal article
Published: 25 March 2020 in Plants
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Flax lignans and neolignans impart health benefits, particularly in treating different types of cancers, due to their strong phytoestrogenic and antioxidant properties. The present study enhances the comprehension on the biosynthesis of antioxidant lignans and neolignans in root-derived in vitro cultures of flax (both callus and adventitious root). The results presented here clearly showed that the adventitious root culture efficiently produced a higher amount of lignans (at day 40) and neolignans (at day 30) than callus culture of flax. High performance liquid chromatography (HPLC) analysis revealed that the accumulations of secoisolariciresinol diglucoside (SDG, 5.5 mg g−1 DW (dry weight)) and dehydrodiconiferyl alcohol glucoside (DCG, 21.6 mg/g DW) were 2-fold higher, while guaiacylglycerol-β-coniferyl alcohol ether glucoside (GGCG, 4.9 mg/g DW) and lariciresinol glucoside (LDG, 11.9 mg/g DW) contents were 1.5-fold higher in adventitious root culture than in callus culture. Furthermore, the highest level of total phenolic production (119.01 mg/L), with an antioxidant free radical scavenging activity of 91.01%, was found in adventitious root culture at day 40, while the maximum level of total flavonoid production (45.51 mg/L) was observed in callus culture at day 30 of growth dynamics. These results suggest that adventitious root culture can be a good candidate for scaling up to industrial level to commercially produce these pharmacologically and nutritionally valuable metabolites.

ACS Style

Sumaira Anjum; Amna Komal; Samantha Drouet; Humera Kausar; Christophe Hano; Bilal Haider Abbasi. Feasible Production of Lignans and Neolignans in Root-Derived In Vitro Cultures of Flax (Linum usitatissimum L.). Plants 2020, 9, 409 .

AMA Style

Sumaira Anjum, Amna Komal, Samantha Drouet, Humera Kausar, Christophe Hano, Bilal Haider Abbasi. Feasible Production of Lignans and Neolignans in Root-Derived In Vitro Cultures of Flax (Linum usitatissimum L.). Plants. 2020; 9 (4):409.

Chicago/Turabian Style

Sumaira Anjum; Amna Komal; Samantha Drouet; Humera Kausar; Christophe Hano; Bilal Haider Abbasi. 2020. "Feasible Production of Lignans and Neolignans in Root-Derived In Vitro Cultures of Flax (Linum usitatissimum L.)." Plants 9, no. 4: 409.

Review
Published: 03 February 2020 in Foods
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The efficient progress in nanotechnology has transformed many aspects of food science and the food industry with enhanced investment and market share. Recent advances in nanomaterials and nanodevices such as nanosensors, nano-emulsions, nanopesticides or nanocapsules are intended to bring about innovative applications in the food industry. In this review, the current applications of nanotechnology for packaging, processing, and the enhancement of the nutritional value and shelf life of foods are targeted. In addition, the functionality and applicability of food-related nanotechnologies are also highlighted and critically discussed in order to provide an insight into the development and evaluation of the safety of nanotechnology in the food industry.

ACS Style

Mehwish Shafiq; Sumaira Anjum; Christophe Hano; Iram Anjum; Bilal Haider Abbasi. An Overview of the Applications of Nanomaterials and Nanodevices in the Food Industry. Foods 2020, 9, 148 .

AMA Style

Mehwish Shafiq, Sumaira Anjum, Christophe Hano, Iram Anjum, Bilal Haider Abbasi. An Overview of the Applications of Nanomaterials and Nanodevices in the Food Industry. Foods. 2020; 9 (2):148.

Chicago/Turabian Style

Mehwish Shafiq; Sumaira Anjum; Christophe Hano; Iram Anjum; Bilal Haider Abbasi. 2020. "An Overview of the Applications of Nanomaterials and Nanodevices in the Food Industry." Foods 9, no. 2: 148.

Review
Published: 09 December 2019 in Nanomaterials
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Leishmaniasis is a widely distributed protozoan vector-born disease affecting almost 350 million people. Initially, chemotherapeutic drugs were employed for leishmania treatment but they had toxic side effects. Various nanotechnology-based techniques and products have emerged as anti-leishmanial drugs, including liposomes, lipid nano-capsules, metal and metallic oxide nanoparticles, polymeric nanoparticles, nanotubes and nanovaccines, due to their unique properties, such as bioavailability, lowered toxicity, targeted drug delivery, and biodegradability. Many new studies have emerged with nanoparticles serving as promising therapeutic agent for anti-leishmanial disease treatment. Liposomal Amphotericin B (AmB) is one of the successful nano-based drugs with high efficacy and negligible toxicity. A new nanovaccine concept has been studied as a carrier for targeted delivery. This review discusses different nanotechnology-based techniques, materials, and their efficacies in leishmaniasis treatment and their futuristic improvements.

ACS Style

Kiran Saleem; Zainab Khursheed; Christophe Hano; Iram Anjum; Sumaira Anjum. Applications of Nanomaterials in Leishmaniasis: A Focus on Recent Advances and Challenges. Nanomaterials 2019, 9, 1749 .

AMA Style

Kiran Saleem, Zainab Khursheed, Christophe Hano, Iram Anjum, Sumaira Anjum. Applications of Nanomaterials in Leishmaniasis: A Focus on Recent Advances and Challenges. Nanomaterials. 2019; 9 (12):1749.

Chicago/Turabian Style

Kiran Saleem; Zainab Khursheed; Christophe Hano; Iram Anjum; Sumaira Anjum. 2019. "Applications of Nanomaterials in Leishmaniasis: A Focus on Recent Advances and Challenges." Nanomaterials 9, no. 12: 1749.

Journals
Published: 05 December 2019 in RSC Advances
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Advancement in nanomaterials as novel elicitors of plant's specialized secondary metabolites.

ACS Style

Sumaira Anjum; Iram Anjum; Christopher Hano; Sidra Kousar. Advances in nanomaterials as novel elicitors of pharmacologically active plant specialized metabolites: current status and future outlooks. RSC Advances 2019, 9, 40404 -40423.

AMA Style

Sumaira Anjum, Iram Anjum, Christopher Hano, Sidra Kousar. Advances in nanomaterials as novel elicitors of pharmacologically active plant specialized metabolites: current status and future outlooks. RSC Advances. 2019; 9 (69):40404-40423.

Chicago/Turabian Style

Sumaira Anjum; Iram Anjum; Christopher Hano; Sidra Kousar. 2019. "Advances in nanomaterials as novel elicitors of pharmacologically active plant specialized metabolites: current status and future outlooks." RSC Advances 9, no. 69: 40404-40423.