Ala Szczepura

Prof. Dr. Ala Szczepura

orcid

Research Focus & Metrics

Academic Career Length

56Years (1971-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 March 2005 in Postgraduate Medical Journal
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ASAla Szczepura
Ala Szczepura
This paper reviews the research evidence on access to health care by ethnic minority populations, and discusses what might need to be done to improve access to services. Research on the process of care, and the quality of care received, is considered as well as studies examining uptake of services. Changes in legal context are increasing the pressure on healthcare organisations to examine and adapt their services to ensure equitable access. Examples presented include a new UK population cancer screening programme. The main challenges for clinicians, managers, and policy makers in ensuring equitable access are discussed.

1 May 2008 in The Lancet
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Journal Article
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SBS Bellary
S Bellary
JOJp O'HAre
Jp O'HAre
NRNt Raymond
Nt Raymond
AGAnil Gumber
Anil Gumber
SMS Mughal
S Mughal
ABAh Barnett
Ah Barnett

2 October 2008 in BMC Public Health
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Journal Article
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ASAla Szczepura
Ala Szczepura
CPCharlotte Price
Charlotte Price
AGAnil Gumber
Anil Gumber
A number of studies have reported low uptake of cancer screening programmes by South Asian populations in the UK. However, studies to date have not adjusted findings for differences in demographics and socio-economic status of these populations.

1 August 2010 in Health Technology Assessment
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Journal Article
Open access
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SLSe Lamb
Se Lamb
RLR Lall
R Lall
ZHZ Hansen
Z Hansen
ECE Castelnuovo
E Castelnuovo
EWEj Withers
Ej Withers
MUM Underwood
M Underwood
Objectives To estimate the clinical effectiveness of active management (AM) in general practice versus AM plus a group-based, professionally led cognitive behavioural approach (CBA) for subacute and chronic low back pain (LBP) and to measure the cost of each strategy over a period of 12 months and estimate cost-effectiveness. Design Pragmatic multicentred randomised controlled trial with investigator-blinded assessment of outcomes. Setting Fifty-six general practices from seven English regions. Participants People with subacute and chronic LBP who were experiencing symptoms that were at least moderately troublesome. Interventions Participants were randomised (in a ratio of 2 : 1) to receive either AM+CBA or AM alone. Main outcome measures Primary outcomes were the Roland Morris Disability Questionnaire (RMQ) and the Modified Von Korff Scale (MVK), which measure LBP and disability. Secondary outcomes included mental and physical health-related quality of life (Short Form 12-item health survey), health status, fear avoidance beliefs and pain self-efficacy. Cost–utility of CBA was considered from both the UK NHS perspective and a broader health-care perspective, including both NHS costs and costs of privately purchased goods and services related to LBP. Quality-adjusted life-years (QALYs) were calculated from the five-item EuroQoL. Results Between April 2005 and April 2007, 701 participants were randomised: 233 to AM and 468 to AM+CBA. Of these, 420 were female. The mean age of participants was 54 years and mean baseline RMQ was 8.7. Outcome data were obtained for 85% of participants at 12 months. Benefits were seen across a range of outcome measures in favour of CBA with no evidence of group or therapist effects. CBA resulted in at least twice as much improvement as AM. Mean additional improvement in the CBA arm was 1.1 [95% confidence interval (CI) 0.4 to 1.7], 1.4 (95% CI 0.7 to 2.1) and 1.3 (95% CI 0.6 to 2.1) change points in the RMQ at 3, 6 and 12 months respectively. Additional improvement in MVK pain was 6.8 (95% CI 3.5 to 10.2), 8.0 (95% CI 4.3 to 11.7) and 7.0 (95% CI 3.2 to 10.7) points, and in MVK disability was 4.3 (95% CI 0.4 to 8.2), 8.1 (95% CI 4.1 to 12.0) and 8.4 (95% CI 4.4 to 12.4) points at 3, 6 and 12 months respectively. At 12 months, 60% of the AM+CBA arm and 31% of the AM arm reported some or complete recovery. Mean cost of attending a CBA course was £187 per participant with an additional benefit in QALYs of 0.099 and an additional cost of £178.06. Incremental cost-effectiveness ratio was £1786.00. Probability of CBA being cost-effective reached 90% at about £3000 and remained at that level or above; at a cost-effectiveness threshold of £20,000, the CBA group had an almost 100% probability of being considered cost-effective. User perspectives on the acceptability of group treatments were sought through semi-structured interviews. Most were familiar with key messages of AM; most who had attended any group sessions had retained key messages from the sessions and two-thirds talked about a reduction in fear avoidance and changes in their behaviour. Group sessions appeared to provide reassurance, lessen isolation and enable participants to learn strategies from each other. Conclusions Long-term effectiveness and cost-effectiveness of CBA in treating subacute and chronic LBP was shown, making this intervention attractive to patients, clinicians and purchasers. Short-term (3-month) clinical effects were similar to those found in high-quality studies of other therapies and benefits were maintained and increased over the long term (12 months). Cost per QALY was about half that of competing interventions for LBP and because the intervention can be delivered by existing NHS staff following brief training, the back skills training programme could be implemented within the NHS with relative ease. Trial registration Current Controlled Trials ISRCTN37807450. Funding The National Institute for Health Research Health Technology Assessment programme.

5 July 2022 in Clinical Rehabilitation
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Journal Article
Open access
AKAmir J Khan
Amir J Khan
ASAla Szczepura
Ala Szczepura
SPShea Palmer
Shea Palmer
CBChris Bark
Chris Bark
CNCatriona Neville
Catriona Neville
CNCharles Nduka
Charles Nduka
Objective: To conduct a systematic review of the effectiveness of facial exercise therapy for facial palsy patients, updating an earlier broader Cochrane review; and to provide evidence to inform the development of telerehabilitation for these patients.Data Sources: MEDLINE, EMBASE, CINAHL, Cochrane Library, PEDro and AMED for relevant studies published between 01 January 2011 and 30 September 2020.Methods: Predetermined inclusion/exclusion criteria were utilised to shortlist abstracts. Two reviewers independently appraised articles, systematically extracted data and assessed the quality of individual studies and reviews (using GRADE and AMSTAR-2, respectively). Thematic analysis used for evidence synthesis; no quantitative meta-analysis conducted. The review was registered with PROSPERO (CRD42017073067).Results: Seven new randomised controlled trials, nine observational studies, and three quasi-experimental or pilot studies were identified ( n = 854 participants). 75% utilised validated measures to record changes in facial function and/or patient-rated outcomes. High-quality trials (4/7) all reported positive impacts; as did observational studies rated as high/moderate quality (3/9). The benefit of therapy at different time points post-onset and for cases of varying clinical severity is discussed. Differences in study design prevented data pooling to strengthen estimates of therapy effects. Six new review articles identified were all rated critically low quality.Conclusion: The findings of this targeted review reinforce those of the earlier more general Cochrane review. New research studies strengthen previous conclusions about the benefits of facial exercise therapy early in recovery and add to evidence of the value in chronic cases. Further standardisation of study design/outcome measures and evaluation of cost-effectiveness are recommended.

24 November 2004 in Diabetic Medicine
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Journal Article
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JOJ. P. O'HAre
J. P. O'HAre
NRN. T. Raymond
N. T. Raymond
SMS. Mughal
S. Mughal
LDL. Dodd
L. Dodd
WHW. Hanif
W. Hanif
OGon behalf of the UKADS study group
on behalf of the UKADS study group