Avanish Saklani

Prof. Avanish Saklani

Department of Gastrointestinal Surgical Oncology, Tata Memorial Centre, Tata Memorial Hospital, Mumbai 400012, India

Research Focus & Metrics

Academic Career Length

26Years (2001-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 February 2004 in Postgraduate Medical Journal
Verified
Journal Article
Open access
PDF file
TST Sathesh-Kumar
T Sathesh-Kumar
ASAvanish Saklani
Avanish Saklani
RVR Vinayagam
R Vinayagam
RBR L Blackett
R L Blackett
Laparoscopic cholecystectomy is associated with spillage of gall stones in 5%–40% of procedures, but complications occur very rarely. There are, however, isolated case reports describing a range of complications occurring both at a distance from and near to the subhepatic area. This review looks into the various modes of presentation, ways to minimise spillage, treating the complications, and the legal implications.

7 March 2014 in Annals of Surgical Oncology
Verified
Journal Article
Closed access
PDF file
SBSung Uk Bae
Sung Uk Bae
ASAvanish Saklani
Avanish Saklani
DLDae Ro Lim
Dae Ro Lim
DKDong Wook Kim
Dong Wook Kim
HHHyuk Hur
Hyuk Hur
NKNam Kyu Kim
Nam Kyu Kim

14 August 2013 in International Journal of Colorectal Disease
Verified
Journal Article
Closed access
PDF file
ASAvanish Saklani
Avanish Saklani
DLDae Ro Lim
Dae Ro Lim
HHHyuk Hur
Hyuk Hur
BMByung Soh Min
Byung Soh Min
SBSeung Hyuk Baik
Seung Hyuk Baik
NKNam Kyu Kim
Nam Kyu Kim

1 February 2003 in Japanese Journal of Clinical Oncology
Verified
Journal Article
Open access
PDF file
CPC. S. Pramesh
C. S. Pramesh
ASAvanish Saklani
Avanish Saklani
GPGouri H. Pantvaidya
Gouri H. Pantvaidya
AHAnil A. Heroor
Anil A. Heroor
Kikkeri N NareshKikkeri N Naresh
Kikkeri N Naresh
RDRamakant K. Deshpande
Ramakant K. Deshpande
Meningiomas represent about one sixth of all primary neoplasms of the central nervous system. They rarely metastasize outside the intracranial compartment. There are no clear criteria to identify the subset of aggressive tumors which recur locally or metastasize. Histological tumor grade is the most important predictor of recurrence or metastases. We report an unusual case of recurrent metastasis in an extrapleural location and review the literature. Our patient developed recurrent thoracic metastases from an intracranial benign meningioma after a disease-free interval of 8 years. She was successfully managed by wide excision of the metastasis and is currently asymptomatic.

14 September 2021 in BJS Open
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Journal Article
Open access
PDF file
Mufaddal KaziMufaddal Kazi
Mufaddal Kazi
NKN A N Kumar
N A N Kumar
JRJ Rohila
J Rohila
VSV Sukumar
V Sukumar
RER Engineer
R Engineer
ASAvanish Saklani
Avanish Saklani
This study compared the surgical and oncological outcomes of open and minimally invasive pelvic exenteration. Patients who underwent pelvic exenterations for primary locally advanced rectal cancers with invasion of the urogenital organs (central and anterior disease) between August 2013 and September 2020 were reviewed retrospectively. Patients were categorized as undergoing open or minimally invasive surgery (MIS) and these groups were compared for perioperative outcomes and 3-year survival (overall, recurrence-free and local relapse-free survival). Multivariable Cox regression analysis was performed to assess the independent influence of approach of surgery and cancer features on recurrence-free survival (RFS). Of the 158 patients who underwent pelvic exenteration, 97 (61.4 per cent) had open exenterations and 61 (38.6 per cent) patients had an MIS resection (44 patients (72 per cent) using laparoscopy and 17 (28 per cent) using robotic surgery). There were 96 (60.8 per cent) total pelvic exenterations and 62 (39.2 per cent) posterior pelvic exenterations. MIS exenterations had significantly longer operative times (MIS versus open: 640 mins versus 450 mins; P < 0.001) but reduced blood loss (MIS versus open: 900 ml versus 1600 ml; P < 0.001) and abdominal wound infections (MIS versus open: 8.2 versus 17.5 per cent; P = 0.020) without a difference in hospital stay (MIS versus open: 11 versus 12 days; P = 0.620). R0 resection rates and involvement of circumferential resection margins were similar (MIS versus open: 88.5 versus 91.8 per cent, P = 0.490 and 13.1 versus 8.2 per cent, P = 0.342 respectively). At a median follow-up of 29 months, there were no differences in 3-year overall survival (MIS versus open: 79.4 versus 60.2 per cent; P = 0.251), RFS (MIS versus open: 51.9 versus 47.8 per cent; P = 0.922) or local relapse-free survival (MIS versus open: 89.7 versus 75.2 per cent; P = 0.491. On multivariable analysis, approach to surgery had no bearing on RFS, and only known distant metastasis, aggressive histology and inadequate response to neoadjuvant radiation (pathological tumour regression grade greater than 3) predicted worse RFS. MIS exenterations documented longer procedures but resulted in less blood loss and fewer wound infections compared with open surgeries. In the setting of an experienced centre, the hospital stay, R0 resection rates and oncological outcomes at 3 years were similar to those of open exenterations.

1 January 2014 in Annals of Surgical Treatment and Research
Verified
Journal Article
Open access
PDF file
SBSung Uk Bae
Sung Uk Bae
ASAvanish Saklani
Avanish Saklani
HHHyuk Hur
Hyuk Hur
BMByung Soh Min
Byung Soh Min
SBSeung Hyuk Baik
Seung Hyuk Baik
NKNam Kyu Kim
Nam Kyu Kim
Bae SU, et al. Ann Surg Treat Res. 2014 Feb;86(2):76-82. http://dx.doi.org/10.4174/astr.2014.86.2.76