Link prediction aims to identify potential missing triples in knowledge graphs. To get better results, some recent studies have introduced multimodal information to link prediction. However, these methods utilize multimodal information separately and neglect the complicated interaction between different modalities. In this paper, we aim at better modeling the inter-modality information and thus introduce a novel Interactive Multimodal Fusion (IMF) model to integrate knowledge from different modalities. To this end, we propose a two-stage multimodal fusion framework to preserve modality-specific knowledge as well as take advantage of the complementarity between different modalities. Instead of directly projecting different modalities into a unified space, our multimodal fusion module limits the representations of different modalities independent while leverages bilinear pooling for fusion and incorporates contrastive learning as additional constraints. Furthermore, the decision fusion module delivers the learned weighted average over the predictions of all modalities to better incorporate the complementarity of different modalities. Our approach has been demonstrated to be effective through empirical evaluations on several real-world datasets. The implementation code is available online at https://github.com/HestiaSky/IMF-Pytorch.
12 December 2018 in IEEE Transactions on Knowledge and Data Engineering
Set similarity search is a fundamental operation in a variety of applications. While many previous studies focus on threshold based set similarity search and join, few efforts have been paid for KNN set similarity search. In this paper, we propose a transformation based framework to solve the problem of KNN set similarity search, which given a collection of set records and a query set, returns k results with the largest similarity to the query. We devise an effective transformation mechanism to transform sets with various lengths to fixed length vectors which can map similar sets closer to each other. Then, we index such vectors with a tiny tree structure. Next, we propose efficient search algorithms and pruning strategies to perform exact KNN set similarity search. We also design an estimation technique by leveraging the data distribution to support approximate KNN search, which can speed up the search while retaining high recall. Experimental results on real world datasets show that our framework significantly outperforms state-of-the-art methods in both memory and disk based settings.
Nowadays, with the rapid growth of the internet of things (IoT), massive amounts of time series data are being generated. Time series data play an important role in scientific and technological research for conducting experiments and studies to obtain solid and convincing results. However, due to privacy restrictions, limited access to time series data is always an obstacle. Moreover, the limited available open source data are often not suitable because of a small quantity and insufficient dimensionality and complexity. Therefore, time series data generation has become an imperative and promising solution. In this paper, we provide an overview of classical and state-of-the-art time series data generation methods in IoT. We classify the time series data generation methods into four major categories: rule-based methods, simulation-model-based methods, traditional machine-learning-based methods, and deep-learning-based methods. For each category, we first illustrate its characteristics and then describe the principles and mechanisms of the methods. Finally, we summarize the challenges and future directions of time series data generation in IoT. The systematic classification and evaluation will be a valuable reference for researchers in the time series data generation field.
15 February 2025 in npj Systems Biology and Applications
Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung condition characterized by airflow obstruction. Current diagnostic methods primarily rely on identifying prominent features in spirometry (Volume-Flow time series) to detect COPD, but they are not adept at predicting future COPD risk based on subtle data patterns. In this study, we introduce a novel deep learning-based approach, DeepSpiro, aimed at the early prediction of future COPD risk. DeepSpiro consists of four key components: SpiroSmoother for stabilizing the Volume-Flow curve, SpiroEncoder for capturing volume variability-pattern through key patches of varying lengths, SpiroExplainer for integrating heterogeneous data and explaining predictions through volume attention, and SpiroPredictor for predicting the disease risk of undiagnosed high-risk patients based on key patch concavity, with prediction horizons of 1–5 years, or even longer. Evaluated on the UK Biobank dataset, DeepSpiro achieved an AUC of 0.8328 for COPD detection and demonstrated strong predictive performance for future COPD risk (p-value < 0.001). In summary, DeepSpiro can effectively predict the long-term progression of COPD disease.
The healthcare industry faces serious problems with health data. Firstly, health data is fragmented and its quality needs to be improved. Data fragmentation means that it is difficult to integrate the patient data stored by multiple health service providers. The quality of these heterogeneous data also needs to be improved for better utilization. Secondly, data sharing among patients, healthcare service providers and medical researchers is inadequate. Thirdly, while sharing health data, patients’ right to privacy must be protected, and patients should have authority over who can access their data. In traditional health data sharing system, because of centralized management, data can easily be stolen, manipulated. These systems also ignore patient’s authority and privacy. Researchers have proposed some blockchain-based health data sharing solutions where blockchain is used for consensus management. Blockchain enables multiple parties who do not fully trust each other to exchange their data. However, the practice of smart contracts supporting these solutions has not been studied in detail. We propose CrowdMed-II, a health data management framework based on blockchain, which could address the above-mentioned problems of health data. We study the design of major smart contracts in our framework and propose two smart contract structures. We also introduce a novel search contract for searching patients in the framework. We evaluate their efficiency based on the execution costs on Ethereum. Our design improves on those previously proposed, lowering the computational costs of the framework. This allows the framework to operate at scale and is more feasible for widespread adoption.