Om Prakash Choudhary

Dr. Om Prakash Choudhary

orcid

Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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30 September 2023 in Biomedicine & Pharmacotherapy
Verified
Journal Article
Open access
PRPriyanka
Priyanka
MAMai Abdel Haleem Abusalah
Mai Abdel Haleem Abusalah
HCHitesh Chopra
Hitesh Chopra
ASAbhilasha Sharma
Abhilasha Sharma
SMSuhad Asad Mustafa
Suhad Asad Mustafa
JSJyoti Saini
Jyoti Saini
The field of nanotechnology has revolutionised global attempts to prevent, treat, and eradicate infectious diseases in the foreseen future. Nanovaccines have proven to be a valuable pawn in this novel technology. Nanovaccines are made up of nanoparticles that are associated with or prepared with components that can stimulate the host's immune system. In addition to their delivery capabilities, the nanocarriers have been demonstrated to possess intrinsic adjuvant properties, working as immune cell stimulators. Thus, nanovaccines have the potential to promote rapid as well as long-lasting humoral and cellular immunity. The nanovaccines have several possible benefits, including site-specific antigen delivery, increased antigen bioavailability, and a diminished adverse effect profile. To avail these benefits, several nanoparticle-based vaccines are being developed, including virus-like particles, liposomes, polymeric nanoparticles, nanogels, lipid nanoparticles, emulsion vaccines, exomes, and inorganic nanoparticles. Inspired by their distinctive properties, researchers are working on the development of nanovaccines for a variety of applications, such as cancer immunotherapy and infectious diseases. Although a few challenges still need to be overcome, such as modulation of the nanoparticle pharmacokinetics to avoid rapid elimination from the bloodstream by the reticuloendothelial system, The future prospects of this technology are also assuring, with multiple options such as personalised vaccines, needle-free formulations, and combination nanovaccines with several promising candidates.

1 August 2023 in International Journal of Morphology
Verified
Journal Article
Open access
PDF file
Om Prakash ChoudharyOm Prakash Choudhary
Om Prakash Choudhary
JSJyoti Saini
Jyoti Saini
ACAmit Challana
Amit Challana
The integration of artificial intelligence in veterinary medical education has the potential to revolutionize the way students learn veterinary anatomy. ChatGPT, launched by OpenAI in November 2022, has been the fastest-growing artificial intelligence (AI) application as a learning tool in the past few months. ChatGPT is a virtual assistant that provides students with detailed and relevant anatomical knowledge based on internet sources. Apart from the advantages of ChatGPT in veterinary anatomy education, the challenges and limitations must also be considered, as highlighted in this letter. Further research and evaluation are necessary to ensure the optimal integration of the ChatGPT tool into veterinary anatomy education. ChatGPT can provide students with valuable insights and educational support but cannot replace hands-on experiences; dissection-based laboratory sessions remain essential for developing practical skills and spatial understanding in veterinary anatomy education.

4 May 2022 in Human Vaccines & Immunotherapeutics
Verified
Journal Article
Open access
Manish DhawanManish Dhawan
Manish Dhawan
ASAbhilasha Sharma
Abhilasha Sharma
P.Priyanka ..
Priyanka ..
NTNanamika Thakur
Nanamika Thakur
TRTridib Rajkhowa
Tridib Rajkhowa
Om Prakash ChoudharyOm Prakash Choudhary
Om Prakash Choudhary
Since commencement of COVID-19 pandemic, several SARS-CoV-2 variants have emerged amid containment efforts via vaccination. The Delta variant (B.1.617.2), discovered in October 2020, was designated as a VOC by the WHO on May 11, 2021. The enhanced transmissibility of Delta variant has been associated with critical mutations such as D614G, L452R, P681R, and T478K in the S-protein. The increased affinity of the S-protein and ACE2 has been postulated as a key reason for decreased vaccine efficacy. As per evidence, the Delta variant possesses increased transmissibility and decreased vaccine efficacy compared to other VOCs like Alpha and Beta. This has led to concerns regarding the acquisition of novel mutations in the Delta variant and outbreaks in vulnerable communities, including vaccinated people. In this mini-review of Delta variant, we have explained its evolution and characteristics, the impact of spike mutations on infectivity and immune evasion, and measures to combat future outbreaks.

10 February 2023 in Travel Medicine and Infectious Disease
Verified
Journal Article
Open access
PRPriyanka
Priyanka
HCHitesh Chopra
Hitesh Chopra
Om Prakash ChoudharyOm Prakash Choudhary
Om Prakash Choudhary

3 December 2024 in Annals of Anatomy - Anatomischer Anzeiger
Verified
Journal Article
Closed access
Om Prakash ChoudharyOm Prakash Choudhary
Om Prakash Choudhary
SIShofia Saghya Infant
Shofia Saghya Infant
VAVickram As
Vickram As
HCHitesh Chopra
Hitesh Chopra
NMNicoleta Manuta
Nicoleta Manuta

1 September 2020 in Travel Medicine and Infectious Disease
Verified
Journal Article
Closed access
PRPriyanka
Priyanka
Om Prakash ChoudharyOm Prakash Choudhary
Om Prakash Choudhary
ISIndraj Singh
Indraj Singh
GPGautam Patra
Gautam Patra