Sesquiterpenoids, an important class of natural products possessing three isoprene-derived units, are widely distributed across plants and have a variety of biological activities. All sesquiterpenoids are derived from farnesyl pyrophosphate (FPP), a biosynthesis precursor that can form various carbon skeletons. In order to provide a reference for further research and development of these compounds, this review focused on the increasing number of isolated and volatile sesquiterpenoids found to be produced by plants of the Meliaceae family between 1968 and 2023. The related articles were collected from SciFinder, Google Scholar, and PubMed. According to a literature review, several studies were started for more than 55 years on the plant’s stem barks, twigs, leaves, flowers, seeds, and pericarps, where approximately 413 sesquiterpenoid compounds from several groups such as eudesmane, aromadendrane, cadinane, guaiane, bisabolane, furanoeremophilane, humulene, germacrane, and oppositane-type were isolated and identified with some minor products. Additionally, the hypothetical route of sesquiterpenoids biosynthesis from this family was identified, and eudesmane-type was reported to be 27% of the total compounds. The antimicrobial, antidiabetic, antioxidant, antiplasmodial, antiviral, and cytotoxic activities of the isolated compounds and major volatile sesquiterpenoids constituent on essential oil were also evaluated. The result showed the fundamental of using the sesquiterpenoid compounds from the Meliaceae family in traditional medicine and the discovery of new drugs.

Molybdenum (Mo) is one of nutrients that contributes on process of fixing N₂ and it’s contained in growth medium of N₂-fixing bacteria. Bacillus is bacterium that widely used as biofertilizer because it can fix N₂ in the atmosphere and produce phytohormones in form of Indole 3-Acetic Acid (IAA) which are benefical for plant growth. The purpose of this research was to determine the effect of Mo addition on Bacillus consortium in a growth medium of 2%molasses + 10grams peptone + 3grams beef extract against vegetative cell population, spore population and IAA hormone production after incubated for 3, 6 and 9 days. This research was conducted at Soil Biology Laboratory, Faculty of Agriculture, Padjadjaran University. The method to calculate total population of vegetative cells is the serial dilution plate method with 80ºC heating for 30 minutes for total spore population, while the production of IAA hormone was measured using UV-Vis spectrophotometer with Salkowski reagent at a wavelength of 530 nm. All data subjected to Student-t test with p ≤ 0.05. The results of the study by using the Student-t test showed that Mo increased the vegetative cell population on day 3 but did not affect the vegetative cell population on day 6 and 9. The spore population of the Bacillus consortium was not determined by Mo. The production of IAA hormone in cultures with Mo was not different from that in cultures without Mo.