Epidemiologic studies indirectly suggest that the inhalation of carbonaceous particulate matter impairs lung function in children. Using the carbon content of airway macrophages as a marker of individual exposure to particulate matter derived from fossil fuel, we sought direct evidence of this association.

Lesbian, Gay, Bisexual, Transgender, Intersex, and Queer (LGBTIQ+) people’s experiences of homelessness is an under-explored area of housing and homelessness studies, despite this group making up 20–40% of homeless populations. Despite this, much of the existing literature focuses on specific elements of LGBTIQ+ homelessness, and often does not consider the intersections of these elements, instead placing them into individual siloes. Our approach is an intersectional one; this paper identifies the key themes in the existing research, and analyses how these themes interact to reinforce the discrimination and stigma faced by LGBTIQ+ people who experience homelessness. This intersectional-systems thinking approach to LGBTIQ+ homelessness can be used to develop well-informed, culturally sensitive support programmes.

Acute rheumatic fever (ARF) and its sequela, rheumatic heart disease (RHD), have largely disappeared from high-income countries. However, in New Zealand (NZ), rates remain unacceptably high in indigenous Māori and Pacific populations. The goal of this study is to identify potentially modifiable risk factors for ARF to support effective disease prevention policies and programmes. A case-control design is used. Cases are those meeting the standard NZ case-definition for ARF, recruited within four weeks of hospitalisation for a first episode of ARF, aged less than 20 years, and residing in the North Island of NZ. This study aims to recruit at least 120 cases and 360 controls matched by age, ethnicity, gender, deprivation, district, and time period. For data collection, a comprehensive pre-tested questionnaire focussed on exposures during the four weeks prior to illness or interview will be used. Linked data include previous hospitalisations, dental records, and school characteristics. Specimen collection includes a throat swab (Group A Streptococcus), a nasal swab (Staphylococcus aureus), blood (vitamin D, ferritin, DNA for genetic testing, immune-profiling), and head hair (nicotine). A major strength of this study is its comprehensive focus covering organism, host and environmental factors. Having closely matched controls enables the examination of a wide range of specific environmental risk factors.

The aim of this study was to identify the optimal cast index (CI) level that reduces the risk of fracture redisplacement. The CI is the ratio of sagittal to coronal width from the inside edges of the cast at the fracture site. Previous studies have used 0.7 as the standard. Case records and radiographs of 1001 children who underwent a manipulation under anesthesia for a displaced fracture of the distal forearm were studied. Redisplacement was defined as > 15 degrees of angulation and/or > 80% of translational displacement on check radiographs at 2 weeks. Angulation (degrees) and translational displacement (%) were measured on the initial and check radiographs. The CI was measured on the check radiographs. The CI has previously been validated in an experimental study. The adequacy of reduction after manipulation was determined by translation and angulation of the radius and ulna in anteroposterior and lateral plain film radiographs. From the 1001 patients who qualified for the study, fracture redisplacement was seen in 107 (10.6%) cases at the 2-week follow-up. A total of 752 (75%) patients had CIs of ≤ 0.8, whereas 249 (25%) had casting indices of ≥ 0.81. In patients with CIs of ≤ 0.8, the displacement rate was only 5.58%. However, in patients with CIs of ≥ 0.81, the displacement rate was 26%. A high CI was the sole factor that was significantly higher in the redisplacement group. No statistically significant difference was seen for age, sex, or surgeon seniority. Statistical differences were not noted in initial angular deformity or initial displacement. The CI is a simple reliable radiographic measurement to predict the redisplacement of forearm fractures in children. A plaster with a CI of > 0.81 is prone to redisplacement. High CIs are associated with redisplacement of fractures and should be avoided when molding casts in distal forearm fractures. Level III--retrospective comparative study.

Background The association between good mental health and housing circumstances is well established. Tenure, household crowding and housing affordability have all been linked to mental health and psychological distress. These cross-sectional relationships are collinear and confounded, and so provide little information on the possible effects of changing housing circumstance on mental health or psychological distress. To do this longitudinal data are needed. Methods In this paper we use the longitudinal data from the 11 500 NZ households in the Survey of Families, Income and Employment (SoFIE), conducted in New Zealand from 2002 to 2010. We examine the cross-sectional associations of housing factors on psychological distress and use fixed-effects modelling of longitudinal data to examine any effects of changes in selected housing factors on changes in psychological distress. Results We show large significant cross-sectional associations between all the housing circumstances and psychological distress. These associations were not present in the fixed-effects models. Only changes in individual deprivation had a significant effect on changes in psychological distress. While a significant effect was found for moves to and from houses with a two-bedroom deficit, the small number of moves of this type means these results are not robust. Conclusions These results show that the effect of house ownership and housing affordability on psychological distress is likely to be confounded in the cross-sectional models. Therefore, marginal changes to these housing factors are unlikely to yield large reductions in psychological distress. Our results suggest that reductions in psychological distress are more likely to be seen through interventions that target individual socioeconomic deprivation and severe household crowding.