Dimitrios A. Lamprou

Prof. Dr. Dimitrios A. Lamprou

School of Pharmacy, Queen's University Belfast, Belfast, UK
orcid

Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 March 2015 in Drug Delivery and Translational Research
Verified
Journal Article
Closed access
PDF file
MBMaria-Lucia Briuglia
Maria-Lucia Briuglia
CRChiara Rotella
Chiara Rotella
AMAmber McFarlane
Amber McFarlane
Dimitrios A. LamprouDimitrios A. Lamprou
Dimitrios A. Lamprou

1 June 2018 in International Journal of Pharmaceutics
Verified
Journal Article
Open access
CPCristiane Patricia Pissinato Pere
Cristiane Patricia Pissinato Pere
SESophia N. Economidou
Sophia N. Economidou
GLGurprit S. Lall
Gurprit S. Lall
CZClémentine Ziraud
Clémentine Ziraud
JBJoshua S. Boateng
Joshua S. Boateng
Dennis DouroumisDennis Douroumis
Dennis Douroumis
In this study, polymeric microneedle patches were fabricated by stereolithography, a 3D printing technique, for the transdermal delivery of insulin. A biocompatible resin was photopolymerized to build pyramid and cone microneedle designs followed by inkjet print coating of insulin formulations. Trehalose, mannitol and xylitol were used as drug carriers with the aim to preserve insulin integrity and stability but also to facilitate rapid release rates. Circular dichroism and Raman analysis demonstrated that all carriers maintained the native form of insulin, with xylitol presenting the best performance. Franz cell release studies were used for in vitro determination of insulin release rates in porcine skin. Insulin was released rapidly within 30 min irrespectively of the microneedle design. 3D printing was proved an effective technology for the fabrication of biocompatible and scalable microneedle patches.

1 September 2019 in Materials Science and Engineering: C
Verified
Journal Article
Closed access
SESophia N. Economidou
Sophia N. Economidou
CPCristiane Patricia Pissinato Pere
Cristiane Patricia Pissinato Pere
ARAndrew Reid
Andrew Reid
Md. Jasim UddinMd. Jasim Uddin
Md. Jasim Uddin
JWJames Windmill
James Windmill
Dennis DouroumisDennis Douroumis
Dennis Douroumis

1 June 2018 in International Journal of Pharmaceutics
Verified
Journal Article
Closed access
SESophia N. Economidou
Sophia N. Economidou
Dimitrios A. LamprouDimitrios A. Lamprou
Dimitrios A. Lamprou
Dennis DouroumisDennis Douroumis
Dennis Douroumis

3 July 2019 in Nature Nanotechnology
Verified
Journal Article
Closed access
PDF file
HLHon S. Leong
Hon S. Leong
KBKimberly S. Butler
Kimberly S. Butler
CBC. Jeffrey Brinker
C. Jeffrey Brinker
MAMay Azzawi
May Azzawi
SCSteve Conlan
Steve Conlan
CPChiara Pastore
Chiara Pastore

1 August 2016 in Chem
Verified
Journal Article
Closed access
EAEnateri V. Alakpa
Enateri V. Alakpa
VJVineetha Jayawarna
Vineetha Jayawarna
ALAyala Lampel
Ayala Lampel
KBKarl V. Burgess
Karl V. Burgess
CWChristopher C. West
Christopher C. West
MDMatthew J. Dalby
Matthew J. Dalby