Colorectal cancer is a diet-related cancer. There is much research into the effects of nutrients on the prevention, modulation, and treatment of colorectal cancer. Researchers are trying to find a correlation between epidemiological observations indicating certain dietary components as the originator in the process of developing colorectal cancer, such as a diet rich in saturated animal fats, and dietary components that could eliminate the impact of harmful elements of the daily nutritional routine, i.e., substances such as polyunsaturated fatty acids, curcumin, or resveratrol. Nevertheless, it is very important to understand the mechanisms underlying how food works on cancer cells. In this case, microRNA (miRNA) seems to be a very significant research target. MiRNAs participate in many biological processes connected to carcinogenesis, progression, and metastasis. However, this is a field with development prospects ahead. In this paper, we review the most significant and well-studied food ingredients and their effects on various miRNAs involved in colorectal cancer.
W artykule przedstawiono możliwości terapii inhalacyjnej astmy za pomocą inhalatorów suchego proszku w dobie pandemii COVID-19. Zwrócono uwagę na inhalatory suchego proszku obecne na polskim rynku zawierające kombinację glikokortykosteroidów wziewnych z długo działającym β2-mimetykiem. Pokazano podobieństwa i różnice między różnymi DPI, akcentując cechy, które są ważne z punktu widzenia pacjenta. Szczegółowo omówiono inhalator Forspiro®, który ma unikalne mechanizmy kontroli używania i poprawności techniki inhalacji, ważne dla chorego w dobie pandemii COVID-19 i teleporad medycznych.