Superoxide is the primary active oxygen form produced in living organisms. Because of superoxide anion radical formation during epinephrine oxidation in alkaline medium, this system is offered in some works for antioxidant activity analysis, however, without enough physicochemical justification. Therefore, the task of developing reliable methods for analyzing the superoxide inhibition activity of various objects is very urgent. In this work, a kinetic model of epinephrine autoxidation in an alkaline medium in the presence of antioxidants of plant origin is proposed. The participation of chain reactions with long oxidation chains in this process is revealed. The limiting stage of the process is a one-electron reduction of oxygen by the anionic forms of the phenolic hydroxyls of epinephrine. The appearance of the absorption maximum at a wavelength of 347 nm during epinephrine autoxidation is associated with adrenolutin formation, which is confirmed by HPLC/UV/MS. No adduct formation between phenolic antioxidants and epinephrine oxidation products was found. The complex U-shaped character of epinephrine autoxidation rate dependence on the content of antioxidants in the reaction system was shown. The study of the kinetics of epinephrine autoxidation in the presence of an individual phenolic plant superoxide inhibitor, chlorogenic acid, was carried out for the first time. The inhibitory effect of yarrow, chamomile, and bur beggar-ticks plant extracts in the adrenaline system was examined.

The article reports on the development of a fundamentally new, effective technology for recycling waste tires using the explosive-circulation technology method, which was implemented in industry at a working factory. The construction of an explosion-circulation reactor, in which tires are destroyed under the influence of an explosion, is described. The main technological stages of the reactor operation include the formation of a tire package with a height of about 2.4 m and a mass of up to 1000 kg; cooling the package by air turbo-cooling machine to a temperature of minus 70–80 °C; placing the package into the reactor; initiating the explosive charge; and removing the tire shedding products with a subsequent granulometric classification of the resulting rubber crumb. The resulting rubber crumb has good wettability, which eliminates the need for an additional technological stage of activating the crumb surface. This made it possible to successfully use the obtained rubber crumb to improve the characteristics of road construction bitumen, the hardness of which at −16 °C decreased from 217 to 161 MPa. Using atomic force microscopy (AFM), gas chromatography, mass spectrometry, GPC, and XPS, it was established that the good wettability of the crumbs is explained by the formation of molecules with polar groups (C-O, C=O, C(O)O, C-S, C-SO_x, Zn-S, O-Si(O)-O) on the crumb surface as a result of the explosion.

The influence of nanoparticles of hydrated C₆₀ fullerene and its N-monoamino acid derivatives on the oxidative metabolism and growth of the mycelial biomass of basidiomycetes during their submerged cultivation was studied. It was found that the supplementation of culture media with nanoparticles of the studied compounds at their final concentration range of 10⁻⁷ to 10⁻¹¹ M significantly increased the resulting biomass, while the severity of the effect in this concentration range changed slightly. That prompted the use of nanomolar concentrations of compounds as reasonable. The most pronounced stimulating effect (an increase in biomass of about 240% with respect to control) was observed when culturing Laetiporus sulphureus, the intrinsically high level of oxidative metabolism of which was significantly lowered by the presence of the studied additives. It was shown that the growth-enhancing action of nanoparticles of fullerene C₆₀ and its derivatives could not be attributed to photochemical reactions, particularly fullerene photoexcitation. Fullerene and its derivatives manifest a growth regulatory effect on bio-objects from different kingdoms of the living world (plants and fungi), which is indicative of these compounds’ mechanism of action based on a direct impact on fundamental, universal for all living beings, biophysical processes, primarily chain free-radical oxidation.