General movements (GMs) have been widely used for the early clinical evaluation of infant brain development, allowing immediate evaluation of potential development disorders and timely rehabilitation. The infants’ general movements can be captured digitally, but the lack of quantitative assessment and well‐trained clinical pediatricians presents an obstacle for many years to achieve wider deployment, especially in low‐resource settings. There is a high potential to explore wearable sensors for movement analysis due to outstanding privacy, low cost, and easy‐to‐use features. This work presents a sparse sensor network with soft wireless IMU devices (SWDs) for automatic early evaluation of general movements in infants. The sparse network consisting of only five sensor nodes (SWDs) with robust mechanical properties and excellent biocompatibility continuously and stably captures full‐body motion data. The proof‐of‐the‐concept clinical testing with 23 infants showcases outstanding performance in recognizing neonatal activities, confirming the reliability of the system. Taken together with a tiny machine learning algorithm, the system can automatically identify risky infants based on the GMs, with an accuracy of up to 100% (99.9%). The wearable sparse sensor network with an artificial intelligence‐based algorithm facilitates intelligent evaluation of infant brain development and early diagnosis of development disorders.
9 March 2026 in Proceedings of the National Academy of Sciences
In situ monitoring of sweat glucose during exercise can provide a real-time and continuous assessment of blood glucose dynamics. However, the relatively poor correlation between sweat and blood glucose concentrations during exercise makes it challenging for blood glucose management (BGM) during exercise therapy for diabetes, along with training for athletes and fitness enthusiasts. This work presents a flexible wireless sweat glucose and pH sensing platform integrated with a pH-based correlation model to accurately predict the continuous changes in blood glucose. The pH-based correlation model calibrates enzyme activity changes in glucose oxidase and accounts for the effects of sweat dilution and filtering during paracellular transport of glucose from interstitial fluid and plasma to sweat during exercise. The correlation model has been validated in both healthy individuals and diabetic patients, revealing distinct blood glucose dynamic patterns between the two cohorts. The observed different glucose fluctuations after the intake of various nutritive foods further facilitate the management of diabetes and allow for the identification of hypo-/hyperglycemic risks during training or fitness exercise. The exercise-based device platform combines continuous blood glucose monitoring with diabetes management through effective treatment evaluation and can also provide early prevention for the at-risk population and reduce or even reverse diabetes.
1 September 2020 in International Journal of Geomechanics
Long-term stability evaluation of unsaturated earth structures has always been one of the most important issues in geotechnical engineering. Most available methods are appropriate for calculating the maximum loads that the structures can resist when the hydraulic state is fixed, and the external loads are monotonically increased. In practical engineering, however, the hydraulic condition is ever changing, and so are the matric suction and the shearing strength of unsaturated soils. In this situation, the obtained minimized collapse loads can no longer be used as reference for the design criterion, which may greatly overestimate the stability of the structures. Classical shakedown analysis is a more appropriate method, which can only consider the variation of the loads but not the variation of hydraulic states. This paper presents a novel formulation for shakedown analysis of unsaturated soils considering both the variation of external loads and the variation of the shearing strength caused by drying–wetting cycles. By using the suction stress-based effective stress of unsaturated soils, the three-phased mixture is dealt with as a single-phased material. The suction-stress equivalent forces are established, and the variation of the hydraulic state is dealt with as the variation of equivalent forces. Numerical formulations are then developed by the combination of the finite-element method and the second-order cone programming. Some shakedown problems are solved, and the effect of hydraulic state variation on the shakedown limits of foundations, pavements, and slopes is studied in detail. It is shown that the neglection of moisture content variation would greatly overestimate the safety of earth structures, and the produced errors become more significant with the increase of the suction-stress increment and the decrease of the shearing strength. The shakedown limit reaches the smallest when both external loads and suction stress are varying. When the variation of equivalent forces is complicated, the loading domain can be approximated by a polyhedron using a uniform distribution of sampling points, and the shakedown factor of safety converges to the true value with the increase of the number of sampling points. Shakedown analysis is necessary in engineering designs when several wetting and drying cycles happen.
Hand function rehabilitation training typically requires monitoring the activation status of muscles directly related to hand function. However, due to factors such as the small surface area for hand-back electrode placement and significant skin deformation, the continuous real-time monitoring of high-quality surface electromyographic (sEMG) signals on the hand-back skin still poses significant challenges. We report a stretchable, flexible, breathable, and self-adhesive epidermal sEMG sensor system. The optimized serpentine structure exhibits a sufficient stretchability and filling ratio, enabling the high-quality monitoring of signals. The carving design minimizes the distribution of connecting wires, providing more space for electrode reservation. The low-cost fabrication design, combined with the cauterization design, facilitates large-scale production. Integrated with customized wireless data acquisition hardware, it demonstrates the real-time multi-channel sEMG monitoring capability for muscle activation during hand function rehabilitation actions. The sensor provides a new tool for monitoring hand function rehabilitation treatments, assessing rehabilitation outcomes, and researching areas such as prosthetic control.
13 July 2026 in Proceedings of the National Academy of Sciences
Reliable and continuous electrophysiological recording is important for health monitoring and human–machine interactions. However, most existing epidermal electrodes suffer from either limited skin–electrode contact during skin deformation and sweating, or unstable connections between soft electrodes and relatively rigid data acquisition systems due to the inherent mechanical mismatch. Besides, their lack of personalization further discourages long-term use, particularly among children, adolescents, and individuals sensitive to stigma. Here, this work presents a paintable, drawn-on-skin dry electrode that forms an ultraconformal interface on hierarchically textured skin topographies with a thickness gradient to minimize interfacial stress, achieving low contact impedance (10.8 kΩ cm 2 ) and high adhesion (~963 kPa) on skin. The resulting electrodes are customizable in shape and color, transforming them from “medical devices” into playful wearable accessories, thus enhancing user compliance and long-term wearability. Moreover, the in situ paintability enables seamless integration with porous silver textile connectors, yielding an interlocked junction with a built-in modulus gradient for stable signal transmission. The versatility of this platform is demonstrated through diverse use cases, including wireless electrocardiogram monitoring during long-term complex daily activities, machine learning-enabled electromyogram for gesture recognition and robotic hand control, and through-hair electroencephalogram detection for neural response analysis. In addition, the absence of image artifact highlights its potential for multimodal MRI imaging and electrophysiology. Overall, this strategy establishes a personalized, scalable platform for next-generation electronic tattoos toward continuous healthcare and interactive bioelectronics.
A significant number of people with disabilities rely on assistive devices, yet these technologies often face limitations, including restricted functionality, inadequate user-centered design, and a lack of standardized evaluation metrics. While upper-limb prosthetics remain a key research focus, existing commercial solutions still fall short of meeting daily reliability and usability needs, leading to high abandonment rates. CYBATHLON integrates assistive technologies into daily living tasks, driving innovation and prioritizing user needs. In CYBATHLON 2024, the HANDSON hand secured first place in the arm prosthesis race, showcasing breakthroughs in human–robot integration. This paper presents the HANDSON hand’s design, core technologies, training strategies, and competition performance, offering insights for advancing multifunctional prosthetic hands to tackle real-world challenges.