Background: The relationship between infant breastfeeding and type 1 diabetes mellitus (DM) is unclear but it has been suggested that there may be a link between many environmental factors, including dietary antigens affecting diabetes epidemiology. The main objective of this study is to investigate nutritional risk factors, especially breastfeeding early in life that may be associated with the development of type 1 DM and to determine the relationship these factors have with the disease. Methods: This research is a case-control study and was carried out in Ege University Children’s Hospital in İzmir, Turkey between 13 January 2020 and 5 March 2020. A total of 246 children aged between 4 and 14 years were included in the study. The case group consisted of patients diagnosed with type 1 DM followed-up by Ege University Children’s Hospital’s Endocrinology Unit and the control group included non-diabetic children attending the same hospital’s General Pediatric Outpatient Clinic. A structured questionnaire was created by the researchers after reviewing the literature related to nutritional and other risk factors for type 1 DM. The questionnaire was administered by interviewing the parents and it was related to the child, mother and family of the child. In this study, breastfeeding duration was defined as the total duration of breastfeeding and exclusive breastfeeding meant that the child received only breast milk from the mother. Results: The mean age at diagnosis was 6.30 ± 4.03 years for cases and 7.48 ± 2.56 years for controls. We found that each monthly increase in exclusive breastfeeding duration provided a 0.83-fold (95% CI 0.72, 0.96) decrease in the risk of type 1 DM. Introduction of cereals in the diet at the sixth month or earlier was associated with a 2.58-fold (95% CI 1.29, 5.16) increased risk. Conclusions: Determining the contribution of exclusive breastfeeding to the disease is important in establishing preventive policies. A longer duration of exclusive breastfeeding may be an important role in preventing the disease. This free intervention that truly works will be cost-effective. Future studies are needed to clarify the role of both exclusive and non-exclusive breastfeeding on the development of type 1 DM.

Background: Non-communicable diseases (NCDs) are a major global concern. This study aimed to examine the prevalence and co-occurrence of lifestyle risk factors among university students.Methods: This analytical, cross-sectional study was conducted between January and April 2022. A total of 485 students were included in the study. Lifestyle risk variables for NCDs included physical inactivity, low fruit and vegetable consumption, alcohol use, tobacco smoking, being overweight/obese, and sugar sweetened beverages consumption.Results: Our results showed that the most frequent risk factor was insufficient physical activity (89.2%), followed by low vegetable (70.5%) and fruit consumption (58.9%). Overall, more than half of the students (51.2%) had four or more risk factors highlighting the urgent need for preventive interventions. The co-occurrence of four or more lifestyle risk factors was significantly greater in students at private universities (aOR: 2.01 95% CI: 1.2; 3.35), those living in student homes (aOR: 3.57 95% CI: 1.96; 6.5), and those with fast food preferences when eating outside (a0R: 2.53 95% CI: 1.62; 3.96).Conclusion: Targeted university-based interventions, such as promoting physical activity, providing affordable nutritious meals, and educating students on healthy lifestyles, are essential to reduce non-communicable disease (NCD) risk among students. Early action fosters lifelong healthy habits, supports healthy aging, and reduces healthcare costs. Future research should focus on refining these strategies to maximize their impact on university populations.

Metabolic syndrome (MetS) imposes a substantial burden on the healthcare systems and economies of countries and is a major public health concern worldwide. MetS is mainly caused by an imbalance between calorie intake and energy expenditure; however, it is recognized that additional variables, such as chronic inflammation, may have the same predictive potential as insulin resistance or MetS components in the genesis of type 2 diabetes and cardiovascular events. More importantly, the early diagnosis or treatment of MetS may significantly reduce the burden on the health systems of the disease with any prevention or biomarker and should not be underestimated. Osteopontin (OPN), also called secreted phosphoprotein 1, is a soluble protein found mostly in body fluids. Studies suggest that serum OPN levels may be an early and new biomarker to predict metabolic and cardiovascular complications significantly associated with some diseases. This review aims to provide specific insight into the new biomarker OPN in MetS. With this purpose, it is examined the link between the MetS cornerstones and OPN. In addition, the interaction between the microbiota and MetS is predicted to be bidirectional, and the microbiota may act as a bridge in this interaction process. Increased OPN levels may have unfavourable consequences for cardiovascular diseases, diabetes, and obesity, all of which are components of MetS. Further studies are required to evaluate the use of OPN levels as a clinical biomarker risk of MetS.

Introduction: The association between secondhand smoking (SHS) and the risk of Type 1 diabetes mellitus (DM) has garnered increasing interest. The aim of this study is to examine whether exposure to SHS is associated with an increased likelihood of Type 1 DM. Methods: This study was designed...

Background: It has been suggested that may be a link between many environmental factors, including dietary antigens affecting diabetes epidemiology. The main objective of this study is to investigate nutritional risk factors, especially breastfeeding early in life that may be associated with the development of Type 1 DM and to determine the relationship of these factors with the disease.Methods: The research is a case-control study and was carried out in Ege University Children's Hospital. A total of 248 children aged between 4-14 years were included in the study. The case group was reached from patients diagnosed with Type 1 DM, who applied the Ege University Children's Hospital’s; the control group was reached non-diabetic children applying to the same hospital.Results: The mean age was found 10.4±3.3 years for cases and 7.4±2.5 years for controls. It was found that each monthly increase in exclusive breastfeeding duration provided a 0.78 fold decrease in the risk of Type 1 DM. Introduction of cereals in the diet at 6th month or earlier was associated with an increased risk of 3.42 fold. Each unit increase in the total number of cigarettes that parents smoked at home had increased the risk of Type 1 DM by 1.15 times. Conclusions: Prolonged exclusive breastfeeding duration was found to be a protective factor for Type I DM, while introducing cereals before the 6th month and parental smoking were found an important risk factor, which might be another subject for further studies.

Introduction: It has been shown that the contribution of beverage energy to total energy intake may increase the risk of diseases in various countries. The aim of this study is to evaluate the relationship between the consumption of added sugar from beverages and nutritional status, anthropometric measurements and biochemical blood parameters in adults. Materials and Methods: This study was designed as an analytical and cross-sectional study and conducted on 100 adult females aged 18-65 who applied to the private diet outpatient clinic in Istanbul/Turkey between November 2020 and April 2021. The demographic characteristics of the individuals were applied to the participants using the food frequency questionnaire, eating habits, physical activity habits and beverage consumption frequency questionnaires. Results: The mean age of the women in the study was 31.8 years . Total energy intake from beverages in women over 25 years old was found to be 145.3 kcal and significantly lower. All women in the study consumed tea and coffee. The consumption rate of all beverages except energy drinks was found to be higher in the younger adults. A positive correlation was found between the results of an insulin resistance test and the total amount of added sugar from the beverages consumed (r=0.297 p=0.043). Conclusions: Lower levels of consumption of sugar-sweetened beverages may result in a lower burden of chronic diseases. Future studies should explore consumption patterns of added sugar beverages and individual-level associations with such consumption.